2023年4月27日
发表者 kimi1006
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2022年11月，北京大学口腔医院国家口腔疾病临床医学研究中心联合首都医科大学附属北京儿童医院在学术期刊上发表题为“Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2Chondrogenic Mesenchymal Cell Involvement”的研究成果。文章首次使用单细胞测序深入研究了腭中缝区域，有助于建立腭中缝膜内成骨模型，并揭示了Piezo2+成软骨向间充质细胞在骨成熟和重塑过程中的潜在分子特征。

新格元在该研究中承担了组织保存与解离、单细胞转录组(GEXSCOPE®)测序以及单细胞数据生信分析等工作。

下面和元小新一起来看一下单细胞如何揭示腭中缝膜内成骨模型吧。

研究背景

腭中缝是上颌骨宽度生长发育的主要部位，也是对上颌宽度发育不足者进行上颌快速扩弓(RME)过程中阻抗的主要来源部位。探索腭中缝成熟骨化过程，阐明其中的潜在机制，有助于确定腭中缝RME的最佳时机与矫形力大小，临床意义重大。然而，与腭中缝相关的机制研究很少，目前腭中缝成熟骨化过程未见单细胞测序相关研究。

思维导图

研究结果

1.小鼠模型腭中缝的组织学染色和Micro-CT分析

随着周龄的增长，腭中缝的弯曲程度增加，4、5周龄时腭中缝形态较直，9周龄时较为弯曲。此外，从4周龄至9周龄，腭中缝宽度减小，骨密度(BMD)、骨体积/组织体积(BV/TV)明显增加。Micro-CT结果提示，随着腭中缝成熟骨化，其形态更加交错、宽度更窄，骨化程度增加，但需要注意的是，腭中缝在9周龄时仍未融合。组织学染色观察验证了Micro-CT分析结果，腭中缝区主要由纤维细胞、纤维和成骨细胞组成，在4周龄时观察到软骨细胞，但在5和9周龄时很少见。

图1 腭中缝的组织学染色及Micro-CT分析(小鼠模型)

2.小鼠模型腭中缝的单细胞RNA测序分析

利用单细胞RNA测序分析腭中缝区域的细胞和分子组成，质量控制后获得45,677个细胞，包括来自4周龄小鼠的16,686个细胞、来自5周龄小鼠的17,053个细胞、以及来自9周龄小鼠的11,938个细胞。确定了5种主要的细胞类型，包括上皮细胞、间充质细胞、免疫细胞、内皮细胞、以及神经细胞(图2A)。

由于间充质细胞在成熟骨化过程中，特别是在骨基质形成中作用至关重要，因此，从整体细胞群中选择间充质细胞进行进一步分析。结果表明间充质细胞由5个不同的簇组成，包括周细胞(标志基因为Acta2、Rgs5、Nes)、成骨向间充质细胞(标志基因为Ibsp、Mmp13、Bglap2)、成软骨向间充质细胞(标志基因为Col2a1、Col9a1、Col9a2、Ucma)、成纤维向间充质细胞(标志基因为Smoc2、Col8a1、Dpep1)、以及神经样细胞(标志基因为Olig2、Rtn1、Elavl4)(图2B)。

拟时序与RNA速率分析显示了各簇间充质细胞的分化轨迹，并进一步表明9簇间充质细胞处于不同的状态。在拟时序分析中，周细胞位于上支，成骨向间充质细胞-1(Ost.b1)位于两个下支，成骨向间充质细胞-2 (Ost.b2)和成骨向间充质细胞-3(Ost.b3)位于右下支，成纤维向间充质细胞-1、2、3(Fib.1、Fib.2、Fib.3)位于左下支(图2C)。RNA速率分析表明，虽然3个成骨向间充质细胞簇起始情况不同，但它们向相同的终点分化(图2D)。

图2 间充质细胞在腭中缝中显示出向成骨细胞、成软骨细胞和成纤维细胞方向分化的潜能

3.不同成骨向间充质细胞簇在腭中缝膜内成骨中的作用

为了描述腭中缝的成骨过程，对成骨向间充质细胞进行了差异表达基因(DEGs)和通路分析。Ost.b1的上调通路与间充质发育和血管生成相关，Ost.b2的上调通路与生物矿化和细胞外基质组织相关，Ost.b3的上调通路与组织重塑、软骨发育和破骨细胞分化相关(图3A、B)。4周龄的成骨向间充质细胞(Ost.b-4w)的上调通路与细胞增殖相关，Ost.b-5w的上调通路与破骨细胞和成骨细胞分化相关，Ost.b-9w的上调通路与软骨内骨形态发生相关(图3C、D)。

进一步分析三个关键时间点各细胞亚簇内成骨向间充质细胞的轨迹。结果表明，Ost.b1主要位于左侧支，Ost.b2主要位于右侧支，Ost.b3分布于左、右分支，这提示每个成骨向间充质细胞亚簇处于不同状态(图3E)。RNA速率分析验证了上述结果(图3F)。

图3 不同成骨向间充质细胞簇在腭中缝膜内成骨中发挥不同的作用

4.Piezo2+成软骨向间充质细胞的鉴定

由于软骨细胞在膜内成骨中可能发挥重要作用，因此，研究者进一步分析了腭中缝区成软骨向间充质细胞的数量、百分比与通路富集状态(图4A、B)。这些细胞中上调的通路与软骨凝集、结缔组织发育和机械刺激感受有关。对成软骨向间充质细胞与其他间充质细胞进行差异基因分析，发现了Piezo2基因的差异表达，这是一个与机械感觉离子通道相关的经典标记基因(图4C)。Piezo2基因的pct.1(0.35)与pct.2(0.037)差异较大，表明Piezo2是成软骨向间充质细胞的特异性基因(图4D)。

图4 scRNA-seq鉴定Piezo2+成软骨向间充质细胞

5.Piezo2+成软骨向间充质细胞可能与感受机械刺激与伤口愈合有关

接下来，研究者进行DEGs与通路富集分析，以明确Piezo2+和Piezo2-成软骨向间充质细胞之间的转录差异(图5A、B)。与Piezo2-相比，Piezo2+成软骨向间充质细胞的机械刺激相关基因(Junb、Fos、lers)表达量更高，并且似乎与伤口愈合、对成纤维细胞生长因子的反应、间充质干细胞和软骨细胞分化等相关(图5C、D)。对Piezo2进行免疫组化染色，验证了Piezo2+成软骨向间充质细胞的存在，佐证了上述结果(图5E)。

图5 Piezo2+成软骨向间充质细胞与感受机械刺激有关

结论

为了探索腭中缝成熟骨化过程的潜在机制，本研究建立了一种小鼠腭中缝模型，结合经典的组织学染色分析、Micro-CT分析、以及前沿的单细胞测序分析，明确了腭中缝的细胞与分子组成。本研究首次使用单细胞RNA测序对腭中缝中的细胞群和成骨过程进行了表征，并发现了Piezo2+成软骨向间充质细胞群，提示间充质细胞有潜力参与腭中缝的成熟骨化过程。成骨向间充质细胞分为3个簇(Ost.b1、Ost.b2、Ost.b3)，在膜内成骨过程中发挥多种作用。间充质细胞增殖、聚集(Ost.b1)、并分化为成骨细胞(Ost.b1、Ost.b2、Ost.b3)；成骨细胞形成骨化中心，分泌类骨质，诱导骨矿化(Ost.b2)，并转化为骨细胞；骨重建贯穿整个过程(Ost.b3)(图6)。此外，Piezo2+成软骨向间充质细胞可能与感受机械刺激有关，并有潜力在腭中缝成骨过程中发挥关键作用。总之，本文对腭中缝成熟骨化过程的研究具有创新性的重要意义。

图6腭中缝成熟骨化过程机制的示意图

参考文献

Lu Gao, Tiansong Xu , Liqi Zhang，et al. Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement.2022 Nov 12;11(22):3585.

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2023年4月23日
发表者 kimi1006
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Nature |首次发现介导膜内成骨的骨膜干细胞，解决了困扰领域内长久的膜内成骨/软骨成骨化的干细胞归属问题-微信文章-仪器谱

撰文丨许韧博士

责编丨迦溆

组织特异性干细胞的鉴定和分化成熟，一直以来都是各器质类疾病研究和癌症发生中的经典问题，决定了药物开发和诊疗策略的方向。长久以来，骨骼研究学者们也一直聚焦于骨髓微环境的干细胞分化“事件”：间充质干细胞分化的成骨细胞和造血干细胞由来的破骨细胞所介导的骨代谢平衡。然而，相比较于研究透彻的造血干细胞系统，间充质干细胞特别是成骨干细胞的鉴定和分化研究，一直以来仍处于相对空白或滞后的状态，成为了深入骨骼和相关疾病研究的“瓶颈”。

近年来，随着单细胞测序技术和共聚焦显微成像的发展和运用，髓内间充质干细胞的鉴定和功能解析逐渐成为学科内新的研究热点。2015年，斯坦福大学Michael T. Longaker研究团队首次在Cell杂志上发文【1】，系统性阐明了小鼠骨骼干细胞的富集策略和“干”性鉴定，解决了困扰学术界以久的成骨干细胞的定义问题。同期，哥伦比亚大学的Timothy C. Wang团队也于Cell报道了Gremlin1 标记的骨骼干细胞的分化潜能【2】。这两项背靠背的研究吹响了骨骼干细胞研究的号角。近期，Michael T. Longaker课题组更是开创性地鉴定了人类骨骼干细胞及其分化的等级关系【3】（Cell突破丨人类骨骼干细胞终于被鉴定出来），为骨骼疾病的精准治疗奠定了分子遗传和发育的理论基础，预示着一场硬组织干细胞的研究“风暴”即将来临。

图一经典骨骼形态解剖学

经典骨骼形态解剖学显示骨骼系统被皮质骨天然隔离成骨腔内环境和骨膜外环境(如图一)。然而，长久以来，骨生物学家们一直专注于髓内多能干细胞的功能和临床运用，却忽略了骨膜潜在的干细胞属性。试验和临床上的大量数据表明，骨骼系统的发育和再生与其包被的骨膜有着千丝万缕的联系，例如骨折的愈合和促骨形成药物的响应等。既然骨膜的功能在生理和病理条件下都如此重要，那么骨膜中的成骨干细胞是否存在？如果存在，它的分化等级和功能又是如何呢？其实早在2013年，布朗大学的Wentian Yang研究团队就已经在Nature发文证实，在关节软骨外膜旁的兰氏结构处（perichondrial groove of Ranvier），存在着一些cathepsin K阳性的类似间质干细胞的分布【4】。文章进一步显示在小鼠的cathepsin K阳性细胞中，敲除Ptpn11会导致内生软骨瘤的形成，潜在证明了cathepsin K不仅仅标记成熟的破骨细胞而且很有可能标记骨膜中的成骨前体细胞或干细胞。

近期，骨膜干细胞的神秘面纱终于被揭开，来自于美国康奈尔大学威尔医学院的Matthew B. Greenblatt研究团队在Nature杂志发表了题为Discovery of a periosteal stem cell mediating intramembranous bone formation的研究快报，首次发现了骨膜干细胞并鉴定了其内成骨的特性，解决了困扰领域内以久的膜内成骨/软骨成骨化的干细胞归属问题。

图二骨膜上间质干细胞来源的细胞

该课题组首先运用Cathepsin K cre 小鼠为主要模型，通过与Rosa-Mt/Mg 小鼠的交配，在体内建立了Cathepsin K cre 阳性细胞的“可视化”体系。共聚焦免疫荧光成像显示Cathepsin K 除了标记成熟的破骨细胞外，的确也可以标记部分骨膜上间质干细胞来源的细胞（图二），这与2013 年Nature论文（Wentian Yang et.al）关于的发现Cathepsin K cre 阳性细胞的描述所一致。接着，作者安排了最关键一步的试验设计，通过鉴定小鼠骨骼干细胞的流式细胞分离方法，发现Cathepsin K 阳性骨膜细胞囊括了骨骼干细胞（CD200+CD105-）；骨，软骨，基质祖细胞(CD200-CD105-)和骨，软骨，基质前体细胞(CD200-CD105+)三大阶层。更为有意思的是：Cathepsin K 阳性骨膜干细胞不表达髓内间充质谱系细胞的经典标记蛋白（CD146;PDGF-alpha;Leptin receptor）。此外，骨膜干细胞还大量富集于小鼠新生颅骨的嵌合位置，暗示其主要作用于膜内成骨而非软骨成骨。

图三单细胞测序验证骨膜干细胞

针对如此特异的Cathepsin K 阳性骨膜干细胞，作者谨慎地运用了一系列经典的干细胞鉴定策略去进一步深入肯定其“干”性。

1.在体外，对骨膜干细胞进行不同分化诱导培养，确定了其生成骨骼、软骨、脂肪的多重潜能；

2. 在体内，将骨膜干细胞移植到肾脏囊腔或是乳腺脂肪层中，进一步确定了其专属的成骨特性-膜内成骨；

3.也是最为关键的一步，将移植肾脏中的类骨形成物（GFP标记）进行再次流式细胞分离，得到的干细胞进行二次移植，肯定了其干细胞可以持续更新和再分化成不同阶层的特性（干细胞的金标准）。紧接着，也是该篇文章的画龙点睛之笔（个人认为也是深受Nature钟爱的特性之一）。作者运用了单细胞测序的新技术和最新生信解析方法（图三），进一步客观验证了骨膜干细胞的存在以及和其他谱系细胞的发育关联。

图四骨折模型中验证了骨损伤诱导了Cathepsin K阳性细胞的扩增

最后，作者通过生理和病理模型肯定了Cathepsin K标记的骨膜干细胞在骨形成和再生中的功用。首先，通过敲除破骨细胞非表达的Osx基因确定了Cathepsin K阳性细胞在皮质骨生成中的特殊功用，并不影响到松质骨的累积。接着，在骨折模型中验证了骨损伤诱导了Cathepsin K阳性细胞的扩增，缺失成骨功能的Cathepsin K阳性细胞会直接导致骨折愈合不连（图四）。最后，作者进一步在人类的骨膜组织中也发现了与小鼠模型类似的Cathepsin K阳性骨膜干细胞并验证了其专属膜内成骨的特性。

总体上来说，该项工作的论述简洁明快，切入点新颖准确，针对骨骼发育中的核心问题：膜内成骨化和软骨成骨化的归属问题，巧妙借鉴前人的研究发现和方法，融合当前最热的技术门类，解答了困扰学术界多年以来的基本问题，值得大家思考和学习。本工作的通讯作者为Matthew B. Greenblatt 博士，康奈尔大学威尔医学院独立PI，是骨骼生物学领域近年来涌现的青年才俊之一。

参考文献：

1、Chan, C. K., Seo, E. Y., Chen, J. Y., Lo, D., McArdle, A., Sinha, R., … & Lu, W. J. (2015). Identification and specification of the mouse skeletal stem cell. Cell, 160(1), 285-298.

2、Worthley, D. L., Churchill, M., Compton, J. T., Tailor, Y., Rao, M., Si, Y., … & Gross, S. (2015). Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell, 160(1), 269-284.

3、Chan, C. K., Gulati, G. S., Sinha, R., Tompkins, J. V., Lopez, M., Carter, A. C., … & Brewer, R. E. (2018). Identification of the Human Skeletal Stem Cell. Cell, 175(1), 43-56.

4、Yang, W., Wang, J., Moore, D. C., Liang, H., Dooner, M., Wu, Q., … & Neel, B. G. (2013). Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling. Nature, 499(7459), 491.

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2023年4月18日
发表者 kimi1006
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Nature | 鉴定出对anti-PD1治疗有反应性的肿瘤抗原特异性CD8+T细胞

撰文 | 雪月

肿瘤抗原是由非同义突变导出的多肽，由人类白细胞抗原（human leukocyte antigens，HLA）呈递，从而被抗肿瘤T细胞识别。但是 HLA等位基因的多样性和临床样本的限制阻碍了针对抗原靶向T细胞谱的研究。

近日，来自加州大学洛杉矶分校的Antoni Ribas 团队在Nature 上发表题为Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy 的文章。该文章建立了发现肿瘤抗原特异性T细胞的方法，并对比了抗PD-1治疗有反应和无反应患者的CD8+T细胞中针对肿瘤抗原的TCR类型。

作者认为在分析免疫检查点阻断剂（immune checkpoint blockade ICB）治疗诱导的肿瘤抗原特异性T细胞反应谱需要高灵敏度的方法，能够在相对较少的患者样本中检测到数百个肿瘤抗原特异性T细胞反应。这些样本包含了从肿瘤活检中扩增的数百万外周血单个核细胞（PBMCs）和浸润肿瘤的淋巴细胞（TILs）。新方法需要提高重建分离的肿瘤抗原特异性T细胞受体（neoTCRs）的抗原特异性的效率。最后还需要评估靶向肿瘤抗原的T细胞的识别以及抗肿瘤活性，用于评估的细胞系需表达突变的肿瘤抗原。满足以上条件将允许分析肿瘤抗原特异性T细胞反应谱。

作者首先收集了11名接受anti-PD1治疗的转移性黑色素瘤患者不同时间点的外周血单核细胞，并且从患者的肿瘤活检样本中建立了肿瘤浸润淋巴细胞培养系和自体肿瘤细胞系。作者对肿瘤活检样本进行全外显子测序和转录组分析，并与相匹配的PBMC的DNA进行比对。这些数据可以用来检测每位患者的6个HLA I类等位基因，检测出特异性的非同义突变，对HLA I类分子递呈推断的肿瘤抗原进行预测。作者对每个患者中的肿瘤抗原肽-HLA进行了优先排序。肽-HLA复合物文库在HEK293细胞中合成，并对蛋白质文库进行DNA条形码编码和荧光多聚化。将文库和患者的PBMC或者从肿瘤活检样本中扩增的淋巴细胞进行孵育，然后将肿瘤抗原特异性T细胞通过单细胞分选捕获，通过条形码分析T细胞的抗原特异性，从而定义抗肿瘤CD8+T细胞识别的突变肿瘤抗原。作者用这种方法分析了11个病人，其中7个对抗PD-1治疗有反应。作者发现抗PD-1治疗有反应的患者的非同义突变数量较高。在分离了肿瘤抗原特异性T细胞后，作者进行了单细胞TCR测序，在抗PD-1治疗有反应的患者中，靶向突变的TCR类型要高于无反应性的患者。作者挑选了22个neoTCR，克隆表达在健康个体来源的T细胞中以验证功能。分析发现在肿瘤抗原-HLA复合物刺激下，表达neoTCR的T细胞会分泌IFNg IL2和TNF。用同样方法进一步分析对抗PD-1无反应的患者，作者发现这些个体中也有肿瘤抗原特异性T细胞，当这些TCR表达在健康个体来源T细胞中也能够对自体肿瘤细胞系产生效应。这些有可能用于个性化细胞转移疗法。

本研究表明抗PD-1免疫疗法的反应性与肿瘤和外周血中多克隆CD8+T细胞的存在相关。新建立的发现肿瘤抗原特异性T细胞的方法有助于改进免疫治疗效果。

原文链接：

https://doi.org/10.1038/s41586-023-05787-1

制版人：十一

转载须知

【原创文章】BioArt原创文章，欢迎个人转发分享，未经允许禁止转载，所刊登的所有作品的著作权均为BioArt所拥有。BioArt保留所有法定权利，违者必究。

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2023年4月16日
发表者 kimi1006
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Cell | 历经13年！破除争议：不是基因突变！表观遗传信息的丢失是衰老的主要驱动因素

iNature

所有生物都经历了熵的增加，表现为遗传和表观遗传信息的损失。在酵母中，随着时间的推移，由于染色质修饰蛋白对DNA断裂的重新定位，导致细胞失去了它们的身份，这是酵母衰老的标志。

2023年1月12日，哈佛医学院David A. Sinclair团队在Cell 在线发表题为“Loss of epigenetic information as a cause of mammalian aging”的研究论文，该研究使用一种称为“ICE”(inducible changes to the epigenome，表观基因组诱导变化)的系统，发现表观遗传信息的紊乱导致小鼠衰老，而恢复表观基因组的完整性可以逆转衰老的迹象。

总之，这些数据与衰老的信息论是一致的，该理论认为表观遗传信息的丢失是衰老的可逆原因。

生命是基于细胞机制和存储在基因组和表观基因组中的信息之间复杂的相互作用，这可以被认为是生物“硬件”和“软件”。衰老是由“硬件”故障引起的，还是由“软件”故障引起的，还是两者都造成的，目前还不清楚。在20世纪50年代，Szilard及Medawar分别独立提出衰老是由DNA损伤引起的突变导致遗传信息丢失引起的。与衰老最相关的DNA损伤类型是双链DNA断裂(DSB)，以每个细胞每天10-50次的速度发生。

然而，最近，关于基因突变是否是衰老的首要驱动因素的问题被提出了。许多类型的老细胞缺乏突变，具有较高突变率的小鼠或人的品系几乎没有显示出过早衰老的证据，哺乳动物可以从旧体细胞克隆出具有正常寿命的新个体。在发育过程中，细胞的身份是由转录网络和染色质结构指定的。为了保持最佳功能，细胞必须通过保存表观遗传信息和低熵状态来保持其身份。

文章模式图（图源自Cell ）

表观遗传信息的丢失，而不是遗传，作为衰老的潜在原因，出现在20世纪90年代的酵母研究中。沉默信息调节复合物(Sir2/3/4)从沉默交配型位点重新定位到不稳定的rDNA是不育的原因，这是酵母衰老的标志，与组蛋白占用的改变、组蛋白修饰(例如H3K56ac和H4K16ac)和基因转录一致。SIR2、组蛋白的过表达或组蛋白甲基转移酶基因SET2的缺失延长了酵母的寿命，这表明表观遗传变化不仅是一种生物标志物，而且是酵母衰老的原因。

与衰老相关的表观遗传变化，包括DNA甲基化(DNAme)模式的变化，H3K4me3, H3K9me3和H3K27me3，也可见于多细胞生物中。例子包括缺乏H3K4三甲基化复合物的蠕虫或过度表达Sir2基因的果蝇的寿命延长，以及长寿裸鼹鼠的相对稳定的表观基因组。许多表观遗传变化遵循特定的模式，包括表观遗传时钟的特定CpGs的甲基化。

哺乳动物表观基因组随时间变化的原因尚不清楚。线索还是来自酵母。酵母中的一个主要驱动因素是DSB，其修复需要表观遗传调控因子Sir2, Hst1, Rpd3, Gcn5和Esa1。染色质修饰剂的重新定位或“RCM”假说和随后的“衰老的信息论”提出，真核生物的衰老是由于转录网络和表观遗传信息随着时间的推移而丢失，由一种保守机制驱动，该机制进化为共同调节对细胞损伤的反应，如DSB或挤压损伤。

为了测试表观遗传变化是否是哺乳动物衰老的原因，该研究开发了系统来降解和重置细胞和小鼠的表观遗传信息。该研究的数据表明，哺乳动物的衰老相当于“软件”问题，是表观遗传信息损坏的结果，可以从现有的备份副本中恢复。

“该研究历经13年，我们相信我们的研究是第一个表明表观遗传变化是哺乳动物衰老的主要驱动因素的研究，”该论文的通讯作者、哈佛医学院David Sinclair说。该团队广泛的一系列实验证实了人们期待已久的事实：DNA变化不是衰老的唯一原因，甚至不是主要原因。相反，研究结果表明，染色质的化学和结构变化在不改变遗传密码本身的情况下加速衰老。

参考消息：

https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7

https://medicalxpress.com/news/2023-01-loss-epigenetic-aging-reverse.html

—END—

内容为【iNature】公众号原创，

转载请写明来源于【iNature】

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2023年4月8日
发表者 kimi1006
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transwell细胞计数

Automatic Cell Counter

What is this?

This repository provides an automatic cell counter algorithm to count cell numbers in 2D microscopy images from Boyden Chamber assay and offers a user interface for further manual correction.

Please star this repository if you like it 🙂

Installation:

This algorithm has been implemented using Python 3.9. To install the necessary packages for this framework run:

pip install -r requirements.txt

If you are using conda first install pip by: conda install pip

Usage:

To run the cell counter, the user can easily input the following code in the terminal.

Require arguments:

-image: The path of the input image or the path of the directory.

python viewer.py --image example_data/8.tif

python viewer.py --image example_data/

Here is a tutorial to set up your Automatic Cell Counter for Windows: Tutorial

Example output:

The user interface will be built based on every input image for manual correction. Inside each image, red dots are used to denote the centers of the detected cells. We also used green dots and red bounding boxes to guide users to pay more attention to those easy-to-make-mistake areas: green dots (detected cells are quite small, perhaps one cell is divided to several parts) and red bounding box (high density areas, perhaps two cells are merged). The user may add dots or delete dots manually based on the automatically detected results.

After manual correction, press the ‘d’ (denotes Done) key on the keyboard to print the updated cell numbers on the terminal and close the current window. When all images are corrected, an excel file named result will be generated which contains both automatically detected cell numbers and corrected cell numbers.

User interface for manual correction:

Example output on the terminal (left) and in the excel (right):

Data:

The target images for this reporsitory are taken from Boyden Chamber assay under the microscope – Brightfield, 20x. The assay is based on a chamber of two medium-filled compartments separated by a microporous membrane. The cells are placed on the top of the chamber and are allowed to migrate/invade through the pores of the membrane into the lower compartment. After a certain time, the cells are fixed and stained with 0.05% Crystal Violet – and the number of cells into the lower compartment are counted to determine the migratory or invading capacity of the cells.

The parameters of this algorithm are determined for image with size of 1550 * 2088. If your images are much smaller or larger than this size, please adjust the parameters.

Example images:

Methods:

How to cite:

@software{ruolin_shen_2022_6390980,
  author       = {Ruolin Shen and
                  Christina Bukas and
                  Marie Piraud},
  title        = {{HelmholtzAI-Consultants-Munich/Automatic-Cell- 
                   Counter: First version of the software}},
  month        = mar,
  year         = 2022,
  publisher    = {Zenodo},
  version      = {v1.0.0},
  doi          = {10.5281/zenodo.6390980},
  url          = {https://doi.org/10.5281/zenodo.6390980}
}

Measure

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2023年4月8日
发表者 kimi1006
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Detection of the separated root canal instrument on panoramic radiograph: A comparison of LSTM and CNN deep learning methods

(14) (PDF) Detection of the separated root canal instrument on panoramic radiograph

Abstract and figures

Objectives:
A separated endodontic instrument is one of the challenging complications of root canal treatment. The purpose of this study was to compare two deep learning methods that are convolutional neural network (CNN) and long short-term memory (LSTM) to detect the separated endodontic instruments on dental radiographs.
Methods:
Panoramic radiographs from the hospital archive were retrospectively evaluated by two dentists. A total of 915 teeth, of which 417 are labeled as “separated instrument” and 498 are labeled as “healthy root canal treatment” were included. A total of six deep learning models, four of which are some varieties of CNN (Raw-CNN, Augmented-CNN, Gabor filtered-CNN, Gabor-filtered-augmented-CNN) and two of which are some varieties of LSTM model (Raw-LSTM, Augmented-LSTM) were trained based on several feature extraction methods with an applied or not applied an augmentation procedure. The diagnostic performances of the models were compared in terms of accuracy, sensitivity, specificity, positive and negative predictive value using ten-fold cross-validation. A McNemar’s tests was employed to figure out if there is a statistically significant difference between performances of the models. Receiver Operating Characteristic (ROC) curves were developed to assess the quality of the performance of the most promising model (Gabor filtered-CNN model) by exploring different cut-off levels in the last decision layer of the model.
Results:
The Gabor filtered-CNN model showed the highest accuracy (84.37 ± 2.79), sensitivity (81.26 ± 4.79), positive predictive value (84.16 ± 3.35) an

…

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Page 1

birpublications.org/dmfrDentomaxillofacial Radiology (2023) 0, 20220209© 2023 The Authors. Published by the British Institute of RadiologyRESEARCH ARTICLEDetection of the separated root canal instrument on panoramicradiograph: a comparison of LSTM and CNN deeplearning methods1Cansu Buyuk, 2Burcin Arican Alpay and 3Fusun Er1Department of Dentomaxillofacial Radiology, Istanbul Okan University, Faculty of Dentistry,İstanbul, Turkey; 2Department ofEndodontics, Bahcesehir University, Faculty of Dentistry,İstanbul, Turkey; 3Information Systems Engineering, Piri Reis University,Faculty of Engineering,İstanbul, TurkeyObjectives:A separated endodontic instrument is one of the challenging complications of rootcanal treatment. The purpose of this study was to compare two deep learning methods that areconvolutional neural network (CNN) and long short-term memory (LSTM) to detect the separatedendodontic instruments on dental radiographs.Methods:Panoramic radiographs from the hospital archive were retrospectively evaluated by twodentists. A total of 915 teeth, of which 417 are labeled as “separated instrument” and 498 are labeledas “healthy root canal treatment” were included. A total of six deep learning models, four of whichare some varieties of CNN (Raw-CNN, Augmented-CNN, Gabor filtered-CNN, Gabor-filtered-augmented-CNN) and two of which are some varieties of LSTM model (Raw-LSTM, Augmented-LSTM) were trained based on several feature extraction methods with an applied or not applied anaugmentation procedure. The diagnostic performances of the models were compared in terms ofaccuracy, sensitivity, specificity, positive- and negative-predictive value using 10-fold cross-validation.A McNemar’s tests was employed to figure out if there is a statistically significant difference betweenperformances of the models. Receiver operating characteristic (ROC) curves were developed toassess the quality of the performance of the most promising model (Gabor filtered-CNN model) byexploring different cut-off levels in the last decision layer of the model.Results:The Gabor filtered-CNN model showed the highest accuracy (84.37 ± 2.79), sensitivity(81.26 ± 4.79), positive-predictive value (84.16 ± 3.35) and negative-predictive value (84.62 ± 4.56with a confidence interval of 80.6 ± 0.0076. McNemar’s tests yielded that the performance of theGabor filtered-CNN model significantly different from both LSTM models (p< 0.01).Conclusions:Both CNN and LSTM models were achieved a high predictive performance onto distinguish separated endodontic instruments in radiographs. The Gabor filtered-CNN modelwithout data augmentation gave the best predictive performance.Dentomaxillofacial Radiology(2023)0, 20220209. doi: 10.1259/dmfr.20220209Cite this article as:Buyuk C, Arican Alpay B, Er F. Detection of the separated root canalinstrument on panoramic radiograph: a comparison of LSTM and CNN deep learningmethods.Dentomaxillofac Radiol(2023) 10.1259/dmfr.20220209.Keywords:Artificial intelligence; CNN; deep learning; LSTM; panoramic radiograph; sepa-rated endodontic instrumentsIntroductionThe common causes offailure in endodontic treat-ments are the persistence of bacteria, inadequate rootcanal filling, poor obturation quality, microleakage, andcomplications ofinstrumentation such as separatedendodontic instruments (SEI).1 The incidence of theSEI in the root canal was reported to range from 0.4 to7.4%.2 In teeth with a SEI, the success of retreatmentCorrespondence to: Cansu Buyuk, E-mail: cansubuyuk@yahoo.comReceived 14 June 2022; revised 08 December 2022; accepted 05 January 2023;published online 24 January 2023

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New

Literature Review

Full-text available

January 2023
Computational and Mathematical Methods in Medicine

Aim:
This comprehensive review is aimed at evaluating the diagnostic and prognostic accuracy of artificial intelligence in endodontic dentistry.

Introduction:
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Artificial Intelligence (AI) for Detection and Localization of Unobturated Second Mesial Buccal (MB2) Canals in Cone-Beam Computed Tomography (CBCT)

The aim of this study was to develop a deep learning model to automatically detect and segment unobturated mesial buccal 2 (MB2) canals on endodontically obturated maxillary molars depicted in CBCT studies. Fifty-seven deidentified CBCT studies of maxillary molars with clinically confirmed unobturated MB2 canals were retrieved from a dental institution radiology database. One-hundred and two maxillary molar roots with and without unobturated MB2 canals were segmented using ITK-SNAP. The data were split into training and testing samples designated to train and evaluate the performance, respectively, of a convolutional neural network (CNN), U-Net. The detection performance revealed a sensitivity of 0.8, a specificity of 1, a high PPV of 1, and a NPV of 0.83 for the testing set, along with an accuracy of 0.9. The segmentation performance of unobturated MB2 canals, assessed using the custom metric, rendered a mean value of 0.3018 for the testing set. The current AI algorithm has the potential to identify obturated and unobturated canals in endodontically treated teeth. However, the AI algorithm is still somewhat affected by metallic artifacts, variations in canal calcifications, and the applied configuration. Thus, further development is needed to improve the algorithm and validate the accuracy using external validation data sets.

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2023年4月8日
发表者 kimi1006
暂无评论

阿里轻量应用服务器开启HTTPS加密访问

轻量应用服务器
wordpress 6.0
nginx 1.22

查了很久google，没找到有用的信息，后来发现不需要怎么改配置文件，就能自己开启加密访问。
我是将我的wordpress.conf和nginx.conf两个文件的内容喂给chatgpt后，它告诉我的这个方法。

第一步：只要从阿里云-ssl证书-下载apache的证书文件（chain.crt，public.crt以及.key的三个文件），虽然服务器用的nginx，但是chatgpt告诉我apache的几个文件就可以用。

第二步：
将下载来的文件，重命名如下：

public证书文件（.crt）：改为www.example.com.crt。
证书密钥文件（.key）：改为www.example.com.key。
chain.crt文件：改为chain.crt。

将这三个文件放在/usr/local/nginx/conf/ssl/目录下。记得备份原来在文件夹里的三个文件。

第三步：
修改wordpress.conf文件，记得用命令修改或者通过filezilla等工具连接服务器后用visual studio code等工具编辑代码，编辑完传回去替换原文件。
我的wordpress.conf在这个路径/usr/local/nginx/conf/vhost
在ssl_certificate的下面一行，添加一行ssl_trusted_certificate /usr/local/nginx/conf/ssl/chain.crt;

第四步：
检查：sudo /usr/local/nginx/sbin/nginx -t
加载重启：sudo /usr/local/nginx/sbin/nginx -s reload

访问你的网站，应该已经自动开启HTTPS了。

点击数：0

2023年4月7日
发表者 kimi1006
暂无评论

小鼠bmsc成骨诱导后基因变化查询

	GeneNames	value1（osteogenic）	value2(normal medium)	log2.Fold_change.	log2.Fold_change..normalized	z.score	p.value	q.value.Benjamini.et.al..1995.	q.value.Storey.et.al..2003.	Signature.p.value…0.001.
1	Mgp	3202.32	469.99	2.768415514105	2.7858696486865	47.857704381527	0	0	0	1
2	Postn	2440.12	298.978	3.0288408641026	3.0462949986841	43.656576660686	0	0	0	1
3	Gsn	2984.37	588.389	2.3425842303452	2.3600383649267	42.138029448341	0	0	0	1
4	Gas6	2095.56	228.046	3.199939059057	3.2173931936385	41.477409100682	0	0	0	1
5	Fth1	2742.07	604.231	2.1820932925604	2.199547427142	38.705318772859	0	0	0	1
6	Acta2	365.152	2051.57	-2.490159342534	-2.4727052079525	-35.672220452012	1.07E-278	3.08E-275	3.08E-275	1
7	Sepp1	1082.88	26.556	5.3496917114851	5.3671458460667	34.259688445447	3.13E-257	7.74E-254	7.74E-254	1
8	Timp3	150.285	1376.46	-3.1951897601081	-3.1777356255266	-33.224529862043	4.76E-242	1.03E-238	1.03E-238	1
9	Mt2	1032.74	36.8023	4.8105373485455	4.8279914831271	33.044045371741	1.89E-239	3.64E-236	3.64E-236	1
10	Snord65	0	1958.18	-11.935297671244	-11.917843536662	-32.675716380165	3.46E-234	5.99E-231	5.99E-231	1
11	Snord99	2257.76	616.798	1.8720221433484	1.8894762779299	31.833791860804	2.21E-222	3.47E-219	3.47E-219	1
12	Cst3	1479.65	243.406	2.6038193213397	2.6212734559212	31.484029976455	1.44E-217	2.07E-214	2.07E-214	1
13	Snord69	481.034	1971.21	-2.0348707060462	-2.0174165714647	-30.872086985161	2.83E-209	3.77E-206	3.77E-206	1
14	Ly6a	1867.89	470.875	1.9879934639854	2.0054475985669	30.116905336502	2.91E-199	3.60E-196	3.60E-196	1
15	Snord70	0	1515.89	-11.565949353334	-11.548495218753	-29.699950370928	7.69E-194	8.88E-191	8.88E-191	1
16	Tagln	245.475	1369.91	-2.4804331062695	-2.462978971688	-29.079450341008	6.53E-186	7.07E-183	7.07E-183	1
18	Lox	0	1276.64	-11.318136041154	-11.300681906573	-27.840987352833	1.38E-170	1.33E-167	1.33E-167	1
19	Scarna17	10334.2	6856.35	0.59191404741613	0.60936818199764	27.527864447288	8.15E-167	7.43E-164	7.43E-164	1
20	Mt1	855.996	78.7001	3.4431666810432	3.4606208156247	27.330096747971	1.86E-164	1.61E-161	1.61E-161	1
21	Ibsp	728.848	49.4982	3.8801700066321	3.8976241412136	26.330893477332	8.50E-153	7.01E-150	7.01E-150	1
22	Rnu73b	261.518	1214.55	-2.2154397292241	-2.1979855946426	-25.582967435633	2.36E-144	1.86E-141	1.86E-141	1
23	Serpine1	382.996	1427.91	-1.8985038204705	-1.881049685889	-25.082002747585	7.82E-139	5.89E-136	5.89E-136	1
24	Tpm1	444.03	1492.28	-1.7487891994601	-1.7313350648786	-24.221579948898	1.32E-129	9.51E-127	9.51E-127	1
25	S100a4	6617.76	4196.78	0.65706013426745	0.67451426884896	24.068750902969	5.31E-128	3.68E-125	3.68E-125	1
26	Hp	482.598	7.91176	5.9306794632746	5.9481335978561	22.917873501187	3.08E-116	2.05E-113	2.05E-113	1
27	Ly6c1	670.492	88.3135	2.9245142219471	2.9419683565286	22.496489923353	4.49E-112	2.88E-109	2.88E-109	1
28	Myl9	179.486	841.703	-2.2294399419189	-2.2119858073374	-21.378903856008	2.10E-101	1.30E-98	1.30E-98	1
29	Snora68	2661.26	1366.32	0.96181405510994	0.97926818969145	20.980908618597	9.80E-98	5.85E-95	5.85E-95	1
30	Tsc22d3	456.007	34.457	3.7261869670092	3.7436411015907	20.544724674069	8.58E-94	4.95E-91	4.95E-91	1
31	Mir6546	1181.05	2419.89	-1.0348714261364	-1.0174172915549	-20.522341412118	1.36E-93	7.60E-91	7.60E-91	1
32	Glul	387.151	15.6209	4.6313468865656	4.6488010211471	20.094179017975	8.30E-90	4.49E-87	4.49E-87	1
33	Actb	2538.66	4214.55	-0.73131140923343	-0.71385727465192	-20.046303051643	2.17E-89	1.14E-86	1.14E-86	1
34	Mir6236	1526.23	624.963	1.2881297051813	1.3055838397628	20.008625450022	4.63E-89	2.36E-86	2.36E-86	1
35	Snord110	481.034	1314.14	-1.4499082053251	-1.4324540707436	-19.805521961555	2.67E-87	1.32E-84	1.32E-84	1
36	Actg2	61.2003	504.563	-3.0434237861879	-3.0259696516064	-19.662444679359	4.52E-86	2.18E-83	2.18E-83	1
37	Serpina3n	491.127	0	10.012198444119	10.029652578701	19.217983070368	2.62E-82	1.23E-79	1.23E-79	1
38	Ctgf	169.825	727.052	-2.0980096976605	-2.080555563079	-19.119127298073	1.75E-81	7.98E-79	7.98E-79	1
39	Snord47	2077.67	3513.71	-0.75802859845582	-0.74057446387431	-18.89531966209	1.25E-79	5.53E-77	5.53E-77	1
40	Snora61	3838.41	2419.89	0.66556735236138	0.68302148694289	18.511962586313	1.65E-76	7.16E-74	7.16E-74	1
41	Mir1892	1229	487.8	1.3331232524638	1.3505773870453	18.427407489692	7.92E-76	3.34E-73	3.34E-73	1
42	S100a10	1410.64	611.422	1.2061094854704	1.223563620052	18.285149502565	1.09E-74	4.48E-72	4.48E-72	1
43	Mir3064	1097.86	2142.33	-0.96448663448312	-0.94703249990161	-18.192739879443	5.89E-74	2.37E-71	2.37E-71	1
44	Lgals1	2010.33	3343.03	-0.73372395926472	-0.71626982468321	-17.899984816105	1.18E-71	4.64E-69	4.64E-69	1
45	Snord22	3151.03	1951.45	0.69127699132589	0.7087311259074	17.321343090964	3.25E-67	1.25E-64	1.25E-64	1
46	Aldh1a1	259.536	7.95223	5.0284313729948	5.0458855075763	16.669943667599	2.17E-62	8.16E-60	8.16E-60	1
47	Mir3960	393.501	59.7226	2.7200184229275	2.737472557509	16.613890791195	5.53E-62	2.04E-59	2.04E-59	1
48	Fabp4	334.639	36.529	3.195491427062	3.2129455616436	16.559505124866	1.37E-61	4.93E-59	4.93E-59	1
49	Anxa1	1924.42	1047.5	0.87747345424298	0.89492758882449	16.540532697348	1.87E-61	6.62E-59	6.62E-59	1
51	Gm25500	0	328.535	-9.3599032639347	-9.3424491293532	-16.393289170417	2.14E-60	7.25E-58	7.25E-58	1
52	Mir5121	80.3314	438.916	-2.4499089375049	-2.4324548029234	-16.338794268706	5.23E-60	1.74E-57	1.74E-57	1
53	Ldha	249.581	749.907	-1.587203580847	-1.5697494462655	-16.006675063337	1.15E-57	3.75E-55	3.75E-55	1
54	Dpep1	237.436	6.54773	5.1804000499302	5.1978541845118	15.997684242295	1.33E-57	4.25E-55	4.25E-55	1
55	Comp	292.447	27.248	3.4239529443589	3.4414070789404	15.937378939009	3.49E-57	1.10E-54	1.10E-54	1
56	Crip1	879.703	340.92	1.3675832946279	1.3850374292094	15.891018432923	7.31E-57	2.26E-54	2.26E-54	1
57	Snord66	290.916	0	9.1844588347378	9.2019129693193	15.663174736597	2.70E-55	8.20E-53	8.20E-53	1
58	Itgbl1	234.341	12.1909	4.2647328455841	4.2821869801656	15.344884620512	3.83E-53	1.14E-50	1.14E-50	1
59	Actg1	616.17	1288.92	-1.0647623745884	-1.0473082400069	-15.331334944339	4.72E-53	1.39E-50	1.39E-50	1
60	Tpm4	470.553	1066.04	-1.1798324390656	-1.1623783044841	-15.167843400559	5.77E-52	1.67E-49	1.67E-49	1
61	Tpm2	152.024	544.122	-1.8396310611393	-1.8221769265578	-15.148674818961	7.73E-52	2.19E-49	2.19E-49	1
62	Gas1	231.224	12.9748	4.1555069453464	4.1729610799279	15.137530432349	9.16E-52	2.56E-49	2.56E-49	1
63	Snord2	422.348	96.1512	2.1350554511404	2.152509585722	14.978321494693	1.02E-50	2.80E-48	2.80E-48	1
64	Timp1	658.396	1326.24	-1.0103143971057	-0.99286026252422	-14.883307371685	4.23E-50	1.14E-47	1.14E-47	1
65	Cxcl12	376.67	75.5911	2.3170128454848	2.3344669800663	14.864480193899	5.60E-50	1.49E-47	1.49E-47	1
66	Ctla2a	212.817	9.02102	4.5601790217485	4.57763315633	14.851872181784	6.77E-50	1.78E-47	1.78E-47	1
67	Col5a2	496.397	1084.29	-1.1271843643159	-1.1097302297344	-14.738315974614	3.66E-49	9.45E-47	9.45E-47	1
69	Igfbp6	432.495	109.043	1.987786294751	2.0052404293325	14.48527066078	1.50E-47	3.77E-45	3.77E-45	1
70	Cdkn1c	195.181	1.62649	6.9069068571656	6.9243609917471	14.32585514958	1.51E-46	3.73E-44	3.73E-44	1
71	Figf	179.174	7.87762	4.5074576663677	4.5249118009492	13.594113193823	4.34E-42	1.06E-39	1.06E-39	1
72	Mir7054	0	201.657	-8.6557596758062	-8.6383055412247	-13.416560150389	4.84E-41	1.16E-38	1.16E-38	1
73	Efemp1	253.42	37.6212	2.7519126147769	2.7693667493584	13.413318097988	5.05E-41	1.20E-38	1.20E-38	1
74	Mir150	197.873	0	8.6284309581806	8.6458850927621	13.364889333758	9.70E-41	2.27E-38	2.27E-38	1
75	Mir3082	1346.26	766.222	0.81312270655778	0.83057684113929	12.980869730555	1.57E-38	3.63E-36	3.63E-36	1
77	Scarna3a	438.318	144.137	1.60453720271	1.6219913372915	12.605590621273	1.97E-36	4.42E-34	4.42E-34	1
78	Mir6942	171.698	0	8.4237294241824	8.4411835587639	12.593712267612	2.29E-36	5.01E-34	4.95E-34	1
79	Mir6996	171.698	0	8.4237294241824	8.4411835587639	12.593712267612	2.29E-36	5.01E-34	4.95E-34	1
80	Mir7231	171.698	0	8.4237294241824	8.4411835587639	12.593712267612	2.29E-36	5.01E-34	4.95E-34	1
82	Aldoa	355.454	772.508	-1.1198870035441	-1.1024328689626	-12.372608845272	3.68E-35	7.76E-33	7.76E-33	1
83	Ifitm2	678.518	303.541	1.1604956906791	1.1779498252606	12.302475692617	8.78E-35	1.83E-32	1.83E-32	1
84	Mmp13	242.123	44.734	2.4362964605073	2.4537505950888	12.269807272337	1.32E-34	2.71E-32	2.71E-32	1
85	Snord32a	594.643	1104.67	-0.89351975844645	-0.87606562386494	-12.229641123037	2.16E-34	4.40E-32	4.40E-32	1
86	Ankrd1	10.3456	158.117	-3.9339032650537	-3.9164491304722	-12.20815365465	2.81E-34	5.66E-32	5.66E-32	1
87	Ptgs2	5.85373	143.499	-4.6155406692318	-4.5980865346503	-12.133016084869	7.06E-34	1.41E-31	1.41E-31	1
88	Serpinh1	769.916	1333.47	-0.79241241052103	-0.77495827593952	-12.097273193873	1.09E-33	2.15E-31	2.15E-31	1
89	Adamts1	250.864	52.0958	2.2676664818026	2.2851206163841	11.975969382976	4.75E-33	9.24E-31	9.24E-31	1
90	Mir7078	0	153.244	-8.259686778603	-8.2422326440215	-11.952251732282	6.32E-33	1.21E-30	1.20E-30	1
91	Snord71	0	153.244	-8.259686778603	-8.2422326440215	-11.952251732282	6.32E-33	1.21E-30	1.20E-30	1
92	Snora78	1163.29	669.614	0.79680919879567	0.81426333337718	11.862188266187	1.86E-32	3.50E-30	3.50E-30	1
93	Mir1894	333	97.4706	1.7724831469668	1.7899372815483	11.77671138006	5.15E-32	9.58E-30	9.58E-30	1
94	Lbp	125.548	2.11979	5.8881738869623	5.9056280215438	11.691224908743	1.41E-31	2.60E-29	2.60E-29	1
95	Mif	199.8	504.232	-1.3355310955111	-1.3180769609296	-11.511614297787	1.15E-30	2.10E-28	2.10E-28	1
96	Snord33	66.7553	273.554	-2.034871363022	-2.0174172284405	-11.495400438798	1.39E-30	2.51E-28	2.51E-28	1
97	Cnn1	20.2017	170.06	-3.0734952351026	-3.0560411005211	-11.467926880801	1.91E-30	3.41E-28	3.41E-28	1
98	Thbs2	179.807	470.636	-1.3881624927785	-1.370708358197	-11.460425935693	2.08E-30	3.68E-28	3.68E-28	1
99	Ifitm3	644.942	304.478	1.0828314337443	1.1002855683258	11.355155604634	6.99E-30	1.22E-27	1.22E-27	1
100	Mir7117	0	135.143	-8.0783429763286	-8.0608888417471	-11.327659575067	9.57E-30	1.66E-27	1.66E-27	1
101	Adm	247.159	58.3004	2.0838617545256	2.1013158891071	11.284854496287	1.56E-29	2.67E-27	2.67E-27	1
102	Mir707	132.084	0	8.0453119060288	8.0627660406103	11.2656293071	1.94E-29	3.29E-27	3.29E-27	1
103	Mir7036b	129.336	0	8.0149800874488	8.0324342220303	11.164412128014	6.09E-29	1.02E-26	1.02E-26	1
104	Cnn2	230.98	540.942	-1.2277059784797	-1.2102518438982	-11.154612467037	6.80E-29	1.13E-26	1.13E-26	1
105	Mir1954	777.086	404.69	0.94125707026812	0.95871120484963	11.130940592362	8.87E-29	1.46E-26	1.46E-26	1
106	Mir7045	128.158	0	8.0017797284908	8.0192338630723	11.120597607631	9.96E-29	1.62E-26	1.61E-26	1
107	Mir7237	128.158	0	8.0017797284908	8.0192338630723	11.120597607631	9.96E-29	1.62E-26	1.61E-26	1
108	Cyb5a	454.24	182.597	1.3147916915947	1.3322458261762	11.083098743047	1.52E-28	2.43E-26	2.43E-26	1
109	Tmsb10	417.547	805.786	-0.94845814020606	-0.93100400562455	-10.993437694796	4.11E-28	6.53E-26	6.48E-26	1
110	Pgk1	223.53	524.158	-1.2295332885381	-1.2120791539566	-10.993230332365	4.12E-28	6.48E-26	6.48E-26	1
111	Hspa5	370.33	736.499	-0.99187214112621	-0.9744180065447	-10.917486988986	9.51E-28	1.48E-25	1.48E-25	1
112	Il1rn	139.416	13.9954	3.3163715147858	3.3338256493673	10.860308870576	1.78E-27	2.75E-25	2.75E-25	1
114	Pkm	532.415	955.756	-0.84409113436396	-0.82663699978245	-10.82545585716	2.61E-27	3.96E-25	3.96E-25	1
115	Flna	271.34	588.56	-1.1170877560828	-1.0996336215013	-10.776617198382	4.44E-27	6.68E-25	6.68E-25	1
116	Snord35b	0	118.283	-7.8860989297409	-7.8686447951594	-10.695208782301	1.07E-26	1.60E-24	1.60E-24	1
117	Serping1	148.17	18.7963	2.978732770141	2.9961869047225	10.668513073068	1.43E-26	2.11E-24	2.11E-24	1
118	Rnase4	397.464	155.144	1.3572162917858	1.3746704263673	10.618900373718	2.43E-26	3.57E-24	3.57E-24	1
119	Snord4a	115.022	0	7.8457660183822	7.8632201529638	10.613396326815	2.58E-26	3.76E-24	3.76E-24	1
120	Mir7009	112.189	0	7.8097874180973	7.8272415526788	10.499170825537	8.71E-26	1.25E-23	1.25E-23	1
121	Snord111	112.189	0	7.8097874180973	7.8272415526788	10.499170825537	8.71E-26	1.25E-23	1.25E-23	1
122	Mir678	111.681	0	7.8032399544917	7.8206940890732	10.478492675616	1.08E-25	1.54E-23	1.54E-23	1
123	Txnip	203.087	47.4072	2.098919801686	2.1163739362675	10.275701792967	9.07E-25	1.28E-22	1.28E-22	1
124	Snord15b	1451.28	963.49	0.59098429186249	0.608438426444	10.261445767536	1.05E-24	1.47E-22	1.47E-22	1
125	Cav1	501.499	231.48	1.115359274854	1.1328134094355	10.250586928556	1.18E-24	1.63E-22	1.63E-22	1
126	Mir6929	0	107.116	-7.7430301824362	-7.7255760478547	-10.243611863826	1.26E-24	1.74E-22	1.74E-22	1
127	Mir1905	155.762	395.133	-1.342995026089	-1.3255408915074	-10.234509634427	1.39E-24	1.89E-22	1.89E-22	1
128	Fkbp5	98.2076	3.19871	4.9402725682962	4.9577267028777	10.23013046669	1.45E-24	1.97E-22	1.97E-22	1
129	Hspa9	107.218	314.307	-1.5516272740409	-1.5341731394594	-10.18913613974	2.22E-24	2.98E-22	2.98E-22	1
130	AF357355	104.607	0	7.7088355855984	7.7262897201799	10.184033323471	2.34E-24	3.10E-22	3.09E-22	1
131	Mir6963	104.607	0	7.7088355855984	7.7262897201799	10.184033323471	2.34E-24	3.10E-22	3.09E-22	1
132	Csrp1	164.658	405.339	-1.2996563842905	-1.282202249709	-10.10257205435	5.38E-24	7.06E-22	7.06E-22	1
133	Gapdh	200.478	459.033	-1.1951539457915	-1.17769981121	-10.055367600532	8.70E-24	1.13E-21	1.13E-21	1
134	Mir5133	189.919	43.2369	2.1350492502229	2.1525033848044	10.043505040715	9.81E-24	1.27E-21	1.27E-21	1
135	Ism1	96.564	3.88055	4.6371523897549	4.6546065243364	10.037581599754	1.04E-23	1.34E-21	1.34E-21	1
136	Dstn	333.016	649.469	-0.9636691712941	-0.94621503671259	-10.003901507215	1.47E-23	1.87E-21	1.87E-21	1
137	Col6a1	513.015	245.511	1.063213344049	1.0806674786305	9.9802204320894	1.86E-23	2.35E-21	2.35E-21	1
138	Sbsn	153.112	26.733	2.5178937048077	2.5353478393892	9.9398823600796	2.79E-23	3.50E-21	3.50E-21	1
139	Ppap2b	169.06	34.166	2.306902096441	2.3243562310225	9.9321603908324	3.02E-23	3.76E-21	3.76E-21	1
140	Mir15a	97.8575	0	7.6126105210911	7.6300646556725	9.8908889794962	4.56E-23	5.64E-21	5.64E-21	1
141	Loxl2	58.2329	218.1	-1.9050833980521	-1.8876292634706	-9.8223097653347	9.03E-23	1.11E-20	1.11E-20	1
142	Snord123	77.0448	252.575	-1.7129423544791	-1.6954882198975	-9.8157931703941	9.63E-23	1.17E-20	1.17E-20	1
143	Prdx6	272.981	92.8312	1.5561188673352	1.5735730019167	9.7318479670042	2.21E-22	2.67E-20	2.67E-20	1
145	Igfbp3	85.8653	1.92588	5.4784855073345	5.495939641916	9.6598668298663	4.46E-22	5.33E-20	5.33E-20	1
146	Serpinf1	370.509	688.011	-0.89292304375898	-0.87546890917747	-9.6443353197762	5.19E-22	6.16E-20	6.16E-20	1
147	Fst	194.645	50.3248	1.9515038467776	1.9689579813591	9.6013091984626	7.89E-22	9.30E-20	9.30E-20	1
148	Hspb1	379.021	162.549	1.2214031038209	1.2388572384024	9.5676634742897	1.09E-21	1.28E-19	1.28E-19	1
149	Gja1	333.281	133.112	1.3240984376992	1.3415525722807	9.5439585261323	1.37E-21	1.60E-19	1.60E-19	1
150	Cfl1	535.995	901.814	-0.75061036428604	-0.73315622970453	-9.4785897856157	2.58E-21	2.98E-19	2.98E-19	1
151	Mir7079	0	86.7218	-7.4383227965068	-7.4208686619253	-9.3335165053864	1.02E-20	1.17E-18	1.17E-18	1
152	Tnfrsf12a	58.9231	208.057	-1.8200735891014	-1.8026194545199	-9.2973990949576	1.44E-20	1.64E-18	1.64E-18	1
153	Ramp2	82.585	0	7.4057371640184	7.4231912985999	9.1626249074838	5.07E-20	5.73E-18	5.73E-18	1
155	Snord57	384.474	175.058	1.135053046242	1.1525071808235	9.0997873837276	9.05E-20	1.01E-17	1.01E-17	1
156	Clec2d	156.35	36.0945	2.1149282949669	2.1323824295484	9.0590342805008	1.32E-19	1.46E-17	1.46E-17	1
157	Mir686	373.503	669.457	-0.84187156166884	-0.82441742708733	-9.0382272912122	1.59E-19	1.76E-17	1.76E-17	1
158	Tpi1	168.044	379.559	-1.1754851284834	-1.1580309939019	-9.0213080633541	1.86E-19	2.04E-17	2.04E-17	1
159	Errfi1	238.23	82.283	1.5336888014621	1.5511429360436	8.9965454842459	2.33E-19	2.54E-17	2.54E-17	1
160	Mir99a	98.9366	270.286	-1.4499105599457	-1.4324564253642	-8.9790294445585	2.73E-19	2.96E-17	2.96E-17	1
161	Mir194-1	78.4188	0	7.2931276601377	7.3105817947193	8.9663439904835	3.07E-19	3.30E-17	3.30E-17	1
162	Mir199a-1	0	78.5574	-7.2956752767144	-7.2782211421329	-8.9305957560855	4.24E-19	4.53E-17	4.53E-17	1
163	Snord87	40.1657	164.594	-2.0348758208197	-2.0174216862382	-8.9165644191769	4.81E-19	5.11E-17	5.11E-17	1
164	Atf4	95.8862	263.41	-1.4579150148244	-1.4404608802429	-8.9012361229851	5.52E-19	5.83E-17	5.83E-17	1
165	Scarna13	997.168	651.138	0.61487325048074	0.63232738506225	8.8014877028778	1.35E-18	1.42E-16	1.42E-16	1
167	E030003E18Rik	73.091	2.70022	4.7585449115209	4.7759990461024	8.7740020207842	1.72E-18	1.79E-16	1.79E-16	1
168	Mir1896	356.786	162.451	1.1350543816624	1.1525085162439	8.7659234422195	1.85E-18	1.91E-16	1.91E-16	1
169	Pgam1	203.122	421.647	-1.0536891843886	-1.0362350498071	-8.6899633941752	3.63E-18	3.72E-16	3.72E-16	1
170	Asns	36.9642	151.569	-2.0357741179719	-2.0183199833904	-8.5589395555846	1.14E-17	1.16E-15	1.16E-15	1
171	Ptrf	385.871	186.718	1.0472576096688	1.0647117442503	8.5509941259692	1.22E-17	1.24E-15	1.24E-15	1
172	Mir6926	70.3913	0	7.1373252251353	7.1547793597168	8.5415034841917	1.32E-17	1.33E-15	1.33E-15	1
173	Mir7061	70.3913	0	7.1373252251353	7.1547793597168	8.5415034841917	1.32E-17	1.33E-15	1.33E-15	1
174	DQ267100	209.215	71.4444	1.5500934529604	1.5675475875419	8.4957971938566	1.97E-17	1.96E-15	1.96E-15	1
175	Sned1	117.347	22.1347	2.4063992342526	2.4238533688341	8.4814314580587	2.22E-17	2.20E-15	2.20E-15	1
176	Cald1	147.698	333.877	-1.1766664224687	-1.1592122878872	-8.4677854988646	2.50E-17	2.46E-15	2.46E-15	1
177	Ddit3	20.1554	114.056	-2.5005040226627	-2.4830498880812	-8.4273014856409	3.54E-17	3.46E-15	3.46E-15	1
178	Wisp1	11.5225	92.701	-3.0081311341456	-2.9906769995641	-8.3801039570366	5.29E-17	5.14E-15	5.14E-15	1
179	Dcn	68.5973	3.19727	4.4232393071158	4.4406934416973	8.3760698616151	5.47E-17	5.29E-15	5.29E-15	1
180	Nars	80.5477	224.589	-1.479371969453	-1.4619178348715	-8.3105428933601	9.53E-17	9.17E-15	9.17E-15	1
181	Adamts5	161.285	46.0564	1.8081387173202	1.8255928519017	8.307294289281	9.79E-17	9.37E-15	9.37E-15	1
182	Calm2	346.853	606.949	-0.80725093369397	-0.78979679911246	-8.2939611781098	1.10E-16	1.04E-14	1.04E-14	1
183	Timp2	582.862	338.187	0.78533314420999	0.8027872787915	8.2927747842766	1.11E-16	1.05E-14	1.05E-14	1
184	P4ha1	35.0864	142.704	-2.0240419398227	-2.0065878052412	-8.2733798068168	1.30E-16	1.23E-14	1.23E-14	1
185	Id3	558.058	320.223	0.80133813874007	0.81879227332158	8.2531632441416	1.54E-16	1.44E-14	1.44E-14	1
186	Hpgd	62.5338	1.2078	5.6941827051545	5.711636839736	8.2528608876639	1.55E-16	1.44E-14	1.44E-14	1
187	Csrp2	88.5973	236.162	-1.4144422059293	-1.3969880713478	-8.2356661370503	1.79E-16	1.65E-14	1.65E-14	1
188	Tnc	49.1286	168.315	-1.7765287205569	-1.7590745859754	-8.2221301902883	2.00E-16	1.84E-14	1.84E-14	1
189	Mir202	0	65.212	-7.0270655616064	-7.0096114270249	-8.209828821702	2.22E-16	2.01E-14	2.00E-14	1
190	Mir7013	0	65.212	-7.0270655616064	-7.0096114270249	-8.209828821702	2.22E-16	2.01E-14	2.00E-14	1
191	Mir7027	0	65.212	-7.0270655616064	-7.0096114270249	-8.209828821702	2.22E-16	2.01E-14	2.00E-14	1
192	Snord88a	0	65.212	-7.0270655616064	-7.0096114270249	-8.209828821702	2.22E-16	2.01E-14	2.00E-14	1
193	Lgals3	234.142	90.6129	1.3695953882795	1.387049522861	8.2055548200145	2.30E-16	2.06E-14	2.06E-14	1
194	Myh9	166.366	354.008	-1.0894213412973	-1.0719672067158	-8.1860114636229	2.70E-16	2.41E-14	2.41E-14	1
195	Esd	139.282	313.841	-1.172025013009	-1.1545708784275	-8.1834288143563	2.76E-16	2.45E-14	2.45E-14	1
196	Xdh	100.017	16.5731	2.5933298481483	2.6107839827298	8.1651530726377	3.21E-16	2.84E-14	2.84E-14	1
197	Slc20a1	14.1374	95.9064	-2.7621102725523	-2.7446561379708	-8.1632915876933	3.26E-16	2.87E-14	2.87E-14	1
199	Tnfrsf11b	15.0774	97.6398	-2.6950816733482	-2.6776275387667	-8.1294646585723	4.31E-16	3.75E-14	3.75E-14	1
200	Glipr1	160.631	343.308	-1.0957531325085	-1.078298997927	-8.1000390944821	5.49E-16	4.76E-14	4.76E-14	1
201	Aspn	165.621	50.803	1.7049000135757	1.7223541481572	8.0855510704557	6.19E-16	5.33E-14	5.33E-14	1
203	Tgfb3	46.3355	160.477	-1.7921766963806	-1.7747225617991	-8.0778692803635	6.59E-16	5.62E-14	5.62E-14	1
204	1500015O10Rik	68.2699	4.60768	3.8891372073986	3.9065913419801	8.0638878432235	7.39E-16	6.27E-14	6.27E-14	1
205	Snord8	87.5694	11.9616	2.872016447361	2.8894705819425	8.0570438345428	7.82E-16	6.60E-14	6.60E-14	1
207	Mgst1	134.796	34.6954	1.9579613813437	1.9754155159252	8.0071171666107	1.17E-15	9.82E-14	9.82E-14	1
208	Islr	91.1098	14.1719	2.6845730516572	2.7020271862387	7.9389100703529	2.04E-15	1.70E-13	1.69E-13	1
209	Ndrg2	58.4012	1.57456	5.2129773744167	5.2304315089982	7.9387011611785	2.04E-15	1.69E-13	1.69E-13	1
210	Sult1a1	61.0067	0	7.1876238395835	7.205077974165	7.9381715732567	2.05E-15	1.69E-13	1.69E-13	1
211	Col6a2	245.624	101.842	1.2701188771367	1.2875730117182	7.937301494091	2.07E-15	1.70E-13	1.70E-13	1
212	Tubb5	333.116	576.28	-0.79074530113634	-0.77329116655483	-7.9353788244698	2.10E-15	1.71E-13	1.71E-13	1
213	Npm1	570.511	877.751	-0.62155703140566	-0.60410289682415	-7.8795323537858	3.29E-15	2.67E-13	2.67E-13	1
214	Mir6928	58.1567	0	6.8618735032661	6.8793276378477	7.8298625136373	4.88E-15	3.95E-13	3.95E-13	1
215	Mir425	18.3975	100.52	-2.4499009366019	-2.4324468020204	-7.8184508311298	5.35E-15	4.31E-13	4.31E-13	1
216	Mir694	57.511	0	6.8457660183822	6.8632201529638	7.789756035955	6.71E-15	5.38E-13	5.38E-13	1
217	Angptl2	52.7774	165.385	-1.6478362063568	-1.6303820717753	-7.724347371677	1.12E-14	8.97E-13	8.97E-13	1
218	Tgfbr3	81.6541	11.5258	2.8246584370627	2.8421125716442	7.7156973725392	1.20E-14	9.56E-13	9.56E-13	1
219	Sgk1	414.1	224.825	0.88117673400551	0.89863086858702	7.6949339232169	1.42E-14	1.12E-12	1.12E-12	1
220	Cd34	54.4589	1.24111	5.4554649492866	5.4729190838681	7.6913961231163	1.46E-14	1.15E-12	1.15E-12	1
221	Cemip	14.5538	89.3903	-2.6187223986167	-2.6012682640352	-7.657283890134	1.90E-14	1.49E-12	1.49E-12	1
222	Nov	60.9547	4.11132	3.8900638942732	3.9075180288547	7.6201981416933	2.53E-14	1.98E-12	1.98E-12	1
223	Pdgfra	99.9573	20.3966	2.2929832495612	2.3104373841428	7.6096085612901	2.75E-14	2.13E-12	2.13E-12	1
224	Mir3108	54.6556	0	6.7722974165544	6.7897515511359	7.6088796417258	2.76E-14	2.14E-12	2.14E-12	1
226	Tuba1a	129.936	285.197	-1.1341576075886	-1.1167034730071	-7.5947962462882	3.08E-14	2.36E-12	2.36E-12	1
228	Snord82	70.3913	192.302	-1.4499047318678	-1.4324505972863	-7.573508382768	3.63E-14	2.76E-12	2.76E-12	1
229	Prss23	566.739	344.804	0.71690797362413	0.73436210820564	7.5695033129694	3.75E-14	2.83E-12	2.83E-12	1
230	Wdr1	141.702	301.469	-1.0891495369149	-1.0716954023334	-7.5524699806183	4.27E-14	3.22E-12	3.22E-12	1
231	Gm23450	53.4848	0	6.741057040974	6.7585111755555	7.5329794374983	4.96E-14	3.72E-12	3.72E-12	1
232	Scara5	54.3176	0	7.0377270676898	7.0551812022713	7.5275261097041	5.17E-14	3.86E-12	3.86E-12	1
233	Nqo1	24.248	108.233	-2.1582027783854	-2.1407486438039	-7.5101921690967	5.90E-14	4.39E-12	4.39E-12	1
234	Vegfa	12.9135	83.1767	-2.687299374486	-2.6698452399045	-7.4915146629824	6.81E-14	5.04E-12	5.04E-12	1
235	Mir6363	441.411	250.159	0.81927722487488	0.83673135945639	7.477275030802	7.59E-14	5.59E-12	5.59E-12	1
236	Inhba	20.8158	100.522	-2.271760369873	-2.2543062352915	-7.4731146991707	7.83E-14	5.75E-12	5.75E-12	1
238	Mir134	52.3037	0	6.708841102217	6.7262952367985	7.4553350714088	8.96E-14	6.48E-12	6.44E-12	1
239	Mir6907	52.3037	0	6.708841102217	6.7262952367985	7.4553350714088	8.96E-14	6.48E-12	6.44E-12	1
240	Mir6920	52.3037	0	6.708841102217	6.7262952367985	7.4553350714088	8.96E-14	6.48E-12	6.44E-12	1
241	Mir6995	52.3037	0	6.708841102217	6.7262952367985	7.4553350714088	8.96E-14	6.48E-12	6.44E-12	1
242	Mir6921	50.9421	0	6.6707865283342	6.6882406629157	7.36443147331	1.78E-13	1.27E-11	1.27E-11	1
243	Mir719	109.119	247.72	-1.1828080229328	-1.1653538883513	-7.324470632621	2.40E-13	1.71E-11	1.71E-11	1
244	Mir23a	0	50.5459	-6.6595221684289	-6.6420680338474	-7.2993286990871	2.89E-13	2.05E-11	2.04E-11	1
245	Mir6959	0	50.5459	-6.6595221684289	-6.6420680338474	-7.2993286990871	2.89E-13	2.05E-11	2.04E-11	1
246	Fam162a	68.5644	182.782	-1.4145924037593	-1.3971382691778	-7.2458300376161	4.30E-13	3.03E-11	3.03E-11	1
247	Nupr1	183.093	352.256	-0.94404764510127	-0.92659351051976	-7.2384549230827	4.54E-13	3.18E-11	3.18E-11	1
248	Cryab	175.303	66.3554	1.4015649035214	1.4190190381029	7.2234453806685	5.07E-13	3.54E-11	3.54E-11	1
249	Cxcl14	9.0516	70.0881	-2.9529247782872	-2.9354706437057	-7.2208862400686	5.16E-13	3.59E-11	3.58E-11	1
251	Gm15698	52.3342	2.88088	4.1831725719197	4.2006267065012	7.2145475228818	5.41E-13	3.73E-11	3.73E-11	1
252	Snora26	587.097	370.877	0.66265808305682	0.68011221763833	7.2026044511946	5.91E-13	4.06E-11	4.06E-11	1
253	Mir7019	63.4881	173.444	-1.4499118255695	-1.432457690988	-7.1925648672605	6.36E-13	4.35E-11	4.35E-11	1
254	Aars	43.6378	139.429	-1.6758803851105	-1.658426250529	-7.1793133428101	7.01E-13	4.78E-11	4.78E-11	1
255	Lrrn4cl	115.98	31.9702	1.8590763688749	1.8765305034564	7.1773889138095	7.11E-13	4.83E-11	4.83E-11	1
256	Ngf	7.34568	64.503	-3.1343983066712	-3.1169441720897	-7.1277351102905	1.02E-12	6.90E-11	6.90E-11	1
257	Stim1	66.6044	8.60454	2.9524475145879	2.9699016491694	7.1222919240328	1.06E-12	7.15E-11	7.15E-11	1
258	Mthfd2	10.2179	70.7444	-2.7915172296804	-2.7740630950989	-7.0501850101225	1.79E-12	1.20E-10	1.20E-10	1
259	Snord95	211.174	384.605	-0.86494529908142	-0.84749116449991	-7.0134288616895	2.33E-12	1.55E-10	1.55E-10	1
260	Fmo2	56.2701	0	8.99413808743	9.0115922220115	6.9723480593833	3.12E-12	2.08E-10	2.08E-10	1
261	Tubb6	60.8516	164.789	-1.4372528408991	-1.4197987063176	-6.9640965785137	3.31E-12	2.19E-10	2.19E-10	1
262	Vcl	109.214	239.208	-1.1311078340944	-1.1136536995129	-6.9401053818033	3.92E-12	2.59E-10	2.59E-10	1
264	Cyb5r1	24.0746	99.0976	-2.041338289997	-2.0238841554155	-6.9329347317516	4.12E-12	2.70E-10	2.70E-10	1
265	Prelp	110.256	30.9563	1.8325522164757	1.8500063510572	6.9308930238565	4.18E-12	2.73E-10	2.73E-10	1
266	Fabp5	83.2317	199.692	-1.2625715276594	-1.2451173930779	-6.9297468905934	4.22E-12	2.74E-10	2.74E-10	1
267	Snord17	684.03	457.621	0.57990634162886	0.59736047621037	6.9275174097072	4.28E-12	2.78E-10	2.78E-10	1
268	Mirlet7c-1	44.639	0	6.4802328032552	6.4976869378367	6.9222207349422	4.45E-12	2.87E-10	2.87E-10	1
269	Slc43a3	63.7951	8.59198	2.8923830769344	2.9098372115159	6.9009482834736	5.17E-12	3.33E-10	3.33E-10	1
270	Lurap1l	54.2307	152.41	-1.4907758671237	-1.4733217325422	-6.8856992674926	5.75E-12	3.69E-10	3.69E-10	1
271	Mir3113	136.728	46.691	1.5500923243491	1.5675464589307	6.8679366615164	6.51E-12	4.16E-10	4.16E-10	1
272	Mettl7a1	56.7355	6.17562	3.1995958390576	3.2170499736391	6.8219809483686	8.98E-12	5.72E-10	5.72E-10	1
273	Flnb	70.4116	177.382	-1.332974587084	-1.3155204525025	-6.8167399694691	9.31E-12	5.91E-10	5.91E-10	1
274	Gpx3	186.685	78.8176	1.2440162876358	1.2614704222173	6.8100947516859	9.75E-12	6.16E-10	6.16E-10	1
275	Scpep1	225.633	105.341	1.0989110246783	1.1163651592598	6.7944910767667	1.09E-11	6.84E-10	6.84E-10	1
276	Ccnd1	418.213	248.017	0.75379889663769	0.7712530312192	6.7851071723678	1.16E-11	7.28E-10	7.28E-10	1
277	Mir882	0	43.2369	-6.4341911832941	-6.4167370487125	-6.7816583821341	1.19E-11	7.43E-10	7.43E-10	1
278	Ier3	27.3342	102.121	-1.9015005128509	-1.8840463782694	-6.7123375793806	1.92E-11	1.19E-9	1.19E-9	1
279	Col2a1	39.1198	123.333	-1.656587971197	-1.6391338366154	-6.6959799552196	2.14E-11	1.33E-9	1.33E-9	1
280	Mir721	0	42.0958	-6.3956043941781	-6.3781502595966	-6.6959538666658	2.14E-11	1.33E-9	1.33E-9	1
282	Nbl1	178.373	75.4526	1.241254733487	1.2587088680685	6.6453491798407	3.02E-11	1.86E-9	1.86E-9	1
283	Grem2	11.4076	68.1908	-2.5795818097409	-2.5621276751594	-6.6321107705457	3.31E-11	2.02E-9	2.02E-9	1
284	Hipk1	71.3108	13.4509	2.4064178821956	2.4238720167771	6.6116226307015	3.80E-11	2.32E-9	2.32E-9	1
285	Plin4	54.7505	6.38727	3.0996007980378	3.1170549326193	6.606769040241	3.93E-11	2.39E-9	2.39E-9	1
287	Mir191	40.1657	0	6.3278921146294	6.3453462492109	6.5838078907171	4.59E-11	2.77E-9	2.77E-9	1
288	Itm2a	92.8294	24.4461	1.9249774699939	1.9424316045754	6.5712068956416	4.99E-11	3.00E-9	3.00E-9	1
290	Tmem106b	109.95	33.8846	1.6981459582146	1.7156000927961	6.5696802267976	5.04E-11	3.01E-9	3.01E-9	1
291	Sqstm1	218.58	382.078	-0.80570578898545	-0.78825165440394	-6.5688269060523	5.07E-11	3.02E-9	3.02E-9	1
292	Smpd3	44.4849	2.97715	3.9013118923772	3.9187660269587	6.5158309303411	7.23E-11	4.29E-9	4.29E-9	1
293	Snord88c	39.143	0	6.2906824262037	6.3081365607852	6.5031323033486	7.87E-11	4.65E-9	4.65E-9	1
294	Gas7	38.7483	1.04794	5.2085049939917	5.2259591285732	6.4659033594883	1.01E-10	5.93E-9	5.93E-9	1
295	Itga11	44.0153	127.935	-1.5393339994969	-1.5218798649153	-6.4619068121289	1.03E-10	6.07E-9	6.07E-9	1
296	Itm2b	457.929	287.931	0.66940080718532	0.68685494176683	6.4163256570563	1.40E-10	8.17E-9	8.17E-9	1
297	Prkcdbp	257.885	134.438	0.93978687523458	0.95724100981609	6.4027492681509	1.53E-10	8.90E-9	8.90E-9	1
298	Hmox1	92.8324	202.929	-1.1282747291111	-1.1108205945296	-6.3789840723456	1.78E-10	1.04E-8	1.04E-8	1
299	Rbm3	361.603	559.726	-0.63031411738395	-0.61285998280244	-6.372843533343	1.86E-10	1.07E-8	1.07E-8	1
300	Serpina3c	47.7781	0	9.1849026763502	9.2023568109317	6.3473961499362	2.19E-10	1.26E-8	1.26E-8	1
301	Snord89	100.438	30.4874	1.7200201798969	1.7374743144784	6.3350556763525	2.37E-10	1.36E-8	1.36E-8	1
302	Mir370	0	37.3285	-6.2222056317619	-6.2047514971804	-6.3210973515255	2.60E-10	1.49E-8	1.48E-8	1
303	Mir409	0	37.3285	-6.2222056317619	-6.2047514971804	-6.3210973515255	2.60E-10	1.49E-8	1.48E-8	1
304	Ugcg	28.0609	97.3428	-1.7945129919637	-1.7770588573822	-6.2969447106247	3.04E-10	1.73E-8	1.73E-8	1
306	Slc1a5	97.7123	29.4133	1.7320715244775	1.749525659059	6.2787123932232	3.41E-10	1.93E-8	1.93E-8	1
308	Trib3	0	36.5782	-5.4202596183707	-5.4028054837892	-6.2608177753454	3.83E-10	2.15E-8	2.15E-8	1
309	Dbi	312.676	178.046	0.81241846257251	0.82987259715401	6.2486754709218	4.14E-10	2.32E-8	2.32E-8	1
310	DQ267102	261.518	428.666	-0.71294374411366	-0.69548960953215	-6.238625018697	4.41E-10	2.47E-8	2.47E-8	1
311	Txnrd1	30.5555	100.983	-1.7246084485695	-1.707154313988	-6.2364102587658	4.48E-10	2.49E-8	2.49E-8	1
312	Ifi204	65.3728	12.9024	2.341051041895	2.3585051764765	6.2298126686539	4.67E-10	2.59E-8	2.59E-8	1
314	Fhl2	64.5821	156.898	-1.2806207036134	-1.2631665690319	-6.2119949332533	5.23E-10	2.89E-8	2.89E-8	1
315	Atf5	35.944	110.056	-1.6144149277024	-1.5969607931209	-6.2077396371321	5.38E-10	2.96E-8	2.96E-8	1
316	Emb	121.644	44.3609	1.455304621666	1.4727587562475	6.1870847067048	6.13E-10	3.36E-8	3.36E-8	1
317	Add3	66.9413	13.945	2.263148634067	2.2806027686485	6.1787329327391	6.46E-10	3.53E-8	3.53E-8	1
318	Acss3	35.6211	0	6.5914278250768	6.6088819596583	6.1693949547336	6.86E-10	3.73E-8	3.73E-8	1
320	Mir6357	77.0638	19.1392	2.0095227989142	2.0269769334958	6.1569526295501	7.42E-10	4.01E-8	4.01E-8	1
321	Ckb	24.0676	87.9333	-1.8693173271673	-1.8518631925858	-6.1564545697866	7.44E-10	4.01E-8	4.01E-8	1
322	Mir6973b	0	34.7923	-6.1206961486343	-6.1032420140528	-6.1092696320438	1.00E-9	5.38E-8	5.38E-8	1
323	Snhg6	101.873	210.484	-1.0469388343752	-1.0294846997937	-6.1064424735267	1.02E-9	5.46E-8	5.46E-8	1
324	Rnh1	185.032	87.1413	1.0863462553292	1.1038003899107	6.0968080366359	1.08E-9	5.78E-8	5.78E-8	1
325	Serpina3m	57.5426	0	11.007726432317	11.025180566899	6.0852892381855	1.16E-9	6.20E-8	6.20E-8	1
326	Snora65	162.34	293.817	-0.8558993527825	-0.83844521820099	-6.0738776491783	1.25E-9	6.63E-8	6.63E-8	1
327	Plau	33.8455	103.65	-1.6146841813528	-1.5972300467713	-6.0250877686946	1.69E-9	8.95E-8	8.95E-8	1
329	Arl4c	5.0245	45.2595	-3.1711687041408	-3.1537145695593	-6.0026222354145	1.94E-9	1.02E-7	1.02E-7	1
330	Pdp1	49.3195	6.9383	2.8295040470997	2.8469581816812	6.0016104517638	1.95E-9	1.03E-7	1.03E-7	1
331	Id4	58.4743	11.0175	2.4080057894609	2.4254599240424	5.9893062839382	2.11E-9	1.10E-7	1.10E-7	1
332	Usmg5	272.487	434.976	-0.6747483993684	-0.65729426478689	-5.9787158778959	2.25E-9	1.17E-7	1.17E-7	1
333	Tagln2	71.4286	163.12	-1.1913599305595	-1.173905795978	-5.9781646416789	2.26E-9	1.17E-7	1.17E-7	1
335	Tubb3	6.92772	49.4295	-2.834919786627	-2.8174656520455	-5.9404801372158	2.84E-9	1.47E-7	1.47E-7	1
337	Mir466b-3	0	32.4902	-6.0219327193833	-6.0044785848018	-5.9084189200133	3.45E-9	1.77E-7	1.77E-7	1
338	Gars	108.893	216.254	-0.98981560233538	-0.97236146775387	-5.9043112767405	3.54E-9	1.81E-7	1.81E-7	1
339	Il6st	209.96	107.601	0.96442301688262	0.98187715146413	5.9005855201795	3.62E-9	1.85E-7	1.85E-7	1
340	Pfn1	345.615	524.026	-0.60047256097712	-0.58301842639561	-5.8963470446525	3.72E-9	1.89E-7	1.89E-7	1
341	Hist1h2bb	28.8937	92.9441	-1.685608326283	-1.6681541917015	-5.8859835491879	3.96E-9	2.01E-7	2.01E-7	1
343	Suox	61.0694	12.9094	2.2420277219651	2.2594818565466	5.8683001130343	4.40E-9	2.22E-7	2.22E-7	1
344	H19	41.6023	4.43028	3.2311935033968	3.2486476379784	5.8668821167144	4.44E-9	2.24E-7	2.23E-7	1
345	Fgf7	64.939	151.244	-1.219720836624	-1.2022667020425	-5.8665728521193	4.45E-9	2.23E-7	2.23E-7	1
346	Plaur	17.3571	70.871	-2.0296694813684	-2.0122153467869	-5.8409509802707	5.19E-9	2.60E-7	2.60E-7	1
347	Fmo1	33.5416	0	7.5255680586733	7.5430221932549	5.8116153160936	6.19E-9	3.09E-7	3.09E-7	1
348	Fam46b	50.7584	8.44842	2.5868931305197	2.6043472651012	5.8088350885742	6.29E-9	3.13E-7	3.13E-7	1
349	Cfb	32.0161	1.20789	4.7282365959614	4.7456907305429	5.8004846578582	6.61E-9	3.28E-7	3.28E-7	1
350	Mir18	10.1023	55.1969	-2.4499034537216	-2.43244931914	-5.7935868170987	6.89E-9	3.41E-7	3.41E-7	1
351	Gpc1	20.5917	76.3362	-1.8903044310511	-1.8728502964696	-5.7800619890848	7.47E-9	3.68E-7	3.68E-7	1
352	Wnk1	86.8266	27.2745	1.6705843420609	1.6880384766424	5.7717911047653	7.84E-9	3.86E-7	3.86E-7	1
353	Slc16a3	1.21414	32.1415	-4.7264305686832	-4.7089764341017	-5.7686759988995	7.99E-9	3.92E-7	3.92E-7	1
355	Abracl	73.7672	162.267	-1.1373182498856	-1.1198641153041	-5.7415458348392	9.38E-9	4.58E-7	4.58E-7	1
356	Mir7075	0	30.3997	-5.9259851813639	-5.9085310467824	-5.7181388801626	1.08E-8	5.24E-7	5.24E-7	1
357	Hbegf	3.62672	38.5452	-3.409813941961	-3.3923598073795	-5.7172897746673	1.08E-8	5.25E-7	5.25E-7	1
358	Rtn4	139.029	253.736	-0.86794237765029	-0.85048824306878	-5.713454003892	1.11E-8	5.36E-7	5.36E-7	1
360	Idh1	149.976	68.4363	1.1318979831247	1.1493521177062	5.6704614432786	1.42E-8	6.85E-7	6.85E-7	1
361	Snora7a	373.652	237.927	0.65117624609925	0.66863038068076	5.6597641631199	1.52E-8	7.27E-7	7.27E-7	1
362	Clca3a1	31.9836	1.70016	4.2335899062241	4.2510440408056	5.6580405686385	1.53E-8	7.32E-7	7.32E-7	1
363	Snord1c	29.3794	0	5.8767330276821	5.8941871622636	5.6557797684052	1.55E-8	7.40E-7	7.40E-7	1
364	Gzme	9.50278	52.2891	-2.4600887038064	-2.4426345692249	-5.6525398226085	1.58E-8	7.52E-7	7.52E-7	1
365	Angptl7	29.7201	0	5.1035126394875	5.120966774069	5.6508674554544	1.60E-8	7.57E-7	7.57E-7	1
366	Mterf4	61.8408	14.6384	2.0788011093098	2.0962552438913	5.6358294409165	1.74E-8	8.24E-7	8.24E-7	1
368	Rhoj	99.261	35.914	1.4666806438126	1.4841347783941	5.6209847437593	1.90E-8	8.93E-7	8.93E-7	1
369	Pmp22	157.509	74.4214	1.0816448304612	1.0990989650427	5.605669191253	2.07E-8	9.74E-7	9.74E-7	1
370	Arl4d	44.7929	6.80026	2.7196082604713	2.7370623950528	5.6045004362452	2.09E-8	9.78E-7	9.78E-7	1
371	Glipr2	146.151	260.663	-0.83472611256318	-0.81727197798167	-5.5968952867074	2.18E-8	1.02E-6	1.02E-6	1
372	Mirlet7a-2	50.5114	124.193	-1.2979029260369	-1.2804487914554	-5.5855620759412	2.33E-8	1.08E-6	1.08E-6	1
373	Gda	33.1645	2.37503	3.8036221334895	3.821076268071	5.5794047145279	2.41E-8	1.12E-6	1.12E-6	1
374	Ogn	283.571	168.486	0.75108128121086	0.76853541579236	5.569754699689	2.55E-8	1.18E-6	1.18E-6	1
376	Tinagl1	74.7434	22.1547	1.7543334007036	1.7717875352852	5.5398156856578	3.03E-8	1.39E-6	1.39E-6	1
377	Mir3072	0	28.4828	-5.8320190722153	-5.8145649376338	-5.5363140623496	3.09E-8	1.42E-6	1.42E-6	1
378	Mir493	0	28.4828	-5.8320190722153	-5.8145649376338	-5.5363140623496	3.09E-8	1.42E-6	1.42E-6	1
379	Znhit6	52.5298	10.6212	2.3061893183182	2.3236434528997	5.5352125995772	3.11E-8	1.42E-6	1.42E-6	1
380	Ndnf	43.923	6.75707	2.7005068897833	2.7179610243648	5.5293529144081	3.21E-8	1.46E-6	1.46E-6	1
381	Sptbn1	240.449	136.167	0.82035381688708	0.83780795146859	5.5242728787376	3.31E-8	1.50E-6	1.50E-6	1
382	Scx	4.04068	37.5449	-3.2159469416524	-3.1984928070709	-5.5019173178028	3.76E-8	1.70E-6	1.70E-6	1
383	Cyth3	77.1858	23.8069	1.6969556836569	1.7144098182384	5.5017292336874	3.76E-8	1.70E-6	1.70E-6	1
384	Abca1	47.0076	8.28682	2.504003534285	2.5214576688665	5.4904728551173	4.01E-8	1.81E-6	1.81E-6	1
385	Snta1	69.2097	19.5117	1.8266347697558	1.8440889043373	5.4792414695025	4.27E-8	1.92E-6	1.92E-6	1
386	Mir135a-1	27.5552	0	5.7842526934046	5.8017068279861	5.4785354985525	4.29E-8	1.92E-6	1.92E-6	1
387	Mir369	27.3278	0	5.7722974165544	5.7897515511359	5.455931395193	4.87E-8	2.17E-6	2.17E-6	1
388	Mir5103	27.3278	0	5.7722974165544	5.7897515511359	5.455931395193	4.87E-8	2.17E-6	2.17E-6	1
389	Mir7091	27.3278	0	5.7722974165544	5.7897515511359	5.455931395193	4.87E-8	2.17E-6	2.17E-6	1
390	Nampt	54.5102	12.1289	2.1680774988034	2.1855316333849	5.4319075440438	5.58E-8	2.48E-6	2.48E-6	1
391	Psat1	46.1424	114.596	-1.3123917375313	-1.2949376029498	-5.4124982097164	6.22E-8	2.75E-6	2.75E-6	1
392	Cdh13	41.4126	6.18892	2.7423102035891	2.7597643381706	5.4122398648541	6.22E-8	2.75E-6	2.75E-6	1
393	Dpysl3	27.2188	83.3865	-1.6152103710992	-1.5977562365177	-5.4053936360743	6.47E-8	2.85E-6	2.85E-6	1
394	Mgst3	85.6623	29.6301	1.5315969182333	1.5490510528148	5.3891802704737	7.08E-8	3.11E-6	3.11E-6	1
395	H6pd	76.9242	24.5306	1.6488550132663	1.6663091478478	5.3829829742331	7.33E-8	3.21E-6	3.21E-6	1
396	Plk2	41.0064	105.959	-1.3695851348418	-1.3521310002603	-5.3807902167935	7.42E-8	3.24E-6	3.24E-6	1
397	Gadd45g	101.732	195.433	-0.94190054219844	-0.92444640761693	-5.3807543023329	7.42E-8	3.24E-6	3.24E-6	1
398	Sav1	93.886	34.7174	1.4352511357222	1.4527052703037	5.3801249708254	7.44E-8	3.24E-6	3.24E-6	1
399	Mir496b	0	26.641	-5.7355763314994	-5.7181221969179	-5.3542526093899	8.59E-8	3.73E-6	3.73E-6	1
400	Cped1	39.6978	5.70839	2.7979032483918	2.8153573829733	5.3539156252234	8.61E-8	3.73E-6	3.73E-6	1
401	Adgrg2	33.3437	3.20599	3.3785723719554	3.3960265065369	5.3521949493484	8.69E-8	3.75E-6	3.75E-6	1
402	Fermt2	34.19	94.4006	-1.4652216064585	-1.447767471877	-5.3486608020577	8.86E-8	3.82E-6	3.81E-6	1
403	Snord35a	160.181	79.5637	1.0095207580607	1.0269748926422	5.3485033075496	8.87E-8	3.81E-6	3.81E-6	1
404	Acta1	3.27582	33.9419	-3.3731393353822	-3.3556852008007	-5.3408720029089	9.25E-8	3.96E-6	3.96E-6	1
405	Mir6395	26.1004	0	5.7060000117819	5.7234541463634	5.3318482958469	9.72E-8	4.16E-6	4.16E-6	1
406	Cebpd	99.5693	38.862	1.3573408377084	1.3747949722899	5.3147107170183	1.07E-7	4.56E-6	4.56E-6	1
407	Pfkl	14.1422	58.219	-2.0414834919266	-2.0240293573451	-5.3141451348855	1.07E-7	4.56E-6	4.56E-6	1
408	Hist2h2bb	63.4213	139.2	-1.1341198561893	-1.1166657216078	-5.3055239743078	1.12E-7	4.77E-6	4.77E-6	1
410	Serpine2	156.946	77.9959	1.008798067056	1.0262522016375	5.2911494538082	1.22E-7	5.13E-6	5.13E-6	1
411	H3f3b	115.354	212.243	-0.87964894135513	-0.86219480677362	-5.2865591586619	1.25E-7	5.25E-6	5.25E-6	1
412	Trp53inp1	116.608	50.2529	1.2143880103512	1.2318421449327	5.2827473581672	1.27E-7	5.35E-6	5.35E-6	1
413	Mir28b	25.4711	0	5.6707893603604	5.6882434949419	5.2668127634705	1.39E-7	5.81E-6	5.81E-6	1
414	Mir412	25.4711	0	5.6707893603604	5.6882434949419	5.2668127634705	1.39E-7	5.81E-6	5.81E-6	1
417	Pla2g15	80.0289	27.4488	1.543778000253	1.5612321348345	5.2388441351622	1.62E-7	6.71E-6	6.71E-6	1
418	Map7d2	26.4358	1.11399	4.5686847990584	4.5861389336399	5.2363824091251	1.64E-7	6.78E-6	6.78E-6	1
420	Smpdl3a	71.7108	22.855	1.6496805933337	1.6671347279152	5.1991948086892	2.00E-7	8.25E-6	8.24E-6	1
421	Mir494	0	25.1301	-5.6513445070219	-5.6338903724403	-5.1989389284084	2.00E-7	8.24E-6	8.24E-6	1
423	Phgdh	74.796	153.831	-1.0403132405904	-1.0228591060089	-5.1926135591886	2.07E-7	8.49E-6	8.49E-6	1
424	Snora24	24.7484	0	5.6292633519309	5.6467174865124	5.1908754066672	2.09E-7	8.55E-6	8.55E-6	1
425	Cd109	87.7264	32.8161	1.4186072731204	1.4360614077019	5.155898589934	2.52E-7	1.03E-5	1.03E-5	1
426	Ak3	74.3432	24.784	1.5847917391044	1.6022458736859	5.1452542670586	2.67E-7	1.09E-5	1.09E-5	1
427	Ptk7	36.5862	95.3882	-1.3825112296877	-1.3650570951062	-5.1425925467082	2.71E-7	1.10E-5	1.10E-5	1
428	Cdo1	82.1004	29.562	1.4736453734669	1.4910995080484	5.1298232825629	2.90E-7	1.17E-5	1.17E-5	1
429	Nxn	32.5687	88.6606	-1.4448069909927	-1.4273528564112	-5.1285096488846	2.92E-7	1.18E-5	1.18E-5	1
430	Dkk3	89.7931	173.818	-0.9529009976124	-0.93544686303089	-5.1250408170738	2.97E-7	1.20E-5	1.20E-5	1
431	Nfkbia	51.3865	12.2432	2.0694087077823	2.0868628423638	5.1227153985329	3.01E-7	1.21E-5	1.21E-5	1
432	Sphk1	47.8048	10.5173	2.1843911004108	2.2018452349923	5.1103475088061	3.22E-7	1.29E-5	1.29E-5	1
433	Rasa3	92.1725	36.1104	1.3519219802377	1.3693761148192	5.0981093934142	3.43E-7	1.37E-5	1.37E-5	1
434	Npc2	196.19	109.557	0.84056984145616	0.85802397603767	5.0924590110433	3.53E-7	1.41E-5	1.41E-5	1
435	Mir758	23.7857	0	5.5720225785299	5.5894767131114	5.087540534815	3.63E-7	1.44E-5	1.44E-5	1
436	Ace	30.4533	0	9.1372450212348	9.1546991558164	5.0831132718623	3.71E-7	1.47E-5	1.47E-5	1
439	Il1rl1	4.92971	35.7424	-2.8580618256748	-2.8406076910933	-5.0725937549561	3.92E-7	1.55E-5	1.55E-5	1
440	Ostf1	75.5059	152.458	-1.0137505699935	-0.99629643541197	-5.0583745926733	4.23E-7	1.66E-5	1.66E-5	1
441	Ripk2	12.6915	52.3912	-2.0454619163227	-2.0280077817412	-5.0475767820458	4.47E-7	1.76E-5	1.76E-5	1
442	Ppl	25.0541	0	7.4773063091901	7.4947604437716	5.0325565615318	4.84E-7	1.90E-5	1.90E-5	1
444	Msrb1	57.8842	126.233	-1.124847600098	-1.1073934655164	-5.0184511699203	5.21E-7	2.03E-5	2.03E-5	1
445	Cdsn	5.25206	36.0183	-2.7777747872851	-2.7603206527036	-5.0175351484838	5.23E-7	2.04E-5	2.04E-5	1
446	Tars	47.1118	109.98	-1.2230808325073	-1.2056266979258	-5.013661985249	5.34E-7	2.07E-5	2.07E-5	1
447	Ms4a4d	26.5323	1.83953	3.850340633767	3.8677947683485	5.0107177731992	5.42E-7	2.10E-5	2.10E-5	1
448	Samhd1	71.1992	23.9546	1.571558307861	1.5890124424426	5.0051539724377	5.58E-7	2.16E-5	2.16E-5	1
449	Klf4	66.5157	21.3685	1.6382092676124	1.6556634021939	4.9827590863418	6.27E-7	2.42E-5	2.42E-5	1
450	Myl12a	169.227	276.272	-0.70712958590492	-0.68967545132341	-4.9712043987211	6.65E-7	2.56E-5	2.56E-5	1
451	Cct6a	127.714	222.162	-0.79869538826122	-0.78124125367971	-4.9701126994788	6.69E-7	2.57E-5	2.57E-5	1
452	Eif2s2	69.5592	142.359	-1.0332204583683	-1.0157663237868	-4.9666835946375	6.81E-7	2.61E-5	2.61E-5	1
453	Gpnmb	42.5637	8.72836	2.2858410558952	2.3032951904767	4.9563454608301	7.18E-7	2.75E-5	2.75E-5	1
454	Slc25a30	50.5294	12.7917	1.981915039877	1.9993691744585	4.9411893931358	7.76E-7	2.96E-5	2.96E-5	1
455	Pla2g4a	15.4398	56.4063	-1.8692022410045	-1.851748106423	-4.9305526050427	8.20E-7	3.12E-5	3.12E-5	1
456	Sncg	63.0703	19.7566	1.6746261069815	1.692080241563	4.9275150148004	8.33E-7	3.16E-5	3.16E-5	1
457	Mir1981	22.2518	0	5.4758501386535	5.493304273235	4.9173674563089	8.77E-7	3.32E-5	3.32E-5	1
458	Grn	103.356	45.3409	1.1887372087772	1.2061913433587	4.8916252475591	1.00E-6	3.78E-5	3.77E-5	1
459	Mir19b-1	0	22.2997	-5.4789523964489	-5.4614982618674	-4.8915249863355	1.00E-6	3.77E-5	3.77E-5	1
460	AI607873	22.2915	0	6.489969047641	6.5074231822225	4.8907430503863	1.00E-6	3.78E-5	3.78E-5	1
462	Baiap2	65.8953	21.7385	1.5999231733361	1.6173773079176	4.8770327673071	1.08E-6	4.04E-5	4.04E-5	1
464	Cebpa	43.604	9.73057	2.1638642630939	2.1813183976754	4.8523764791521	1.22E-6	4.55E-5	4.55E-5	1
465	Pik3r1	65.7119	21.8472	1.5887062653192	1.6061603999007	4.8458749277364	1.26E-6	4.69E-5	4.69E-5	1
466	Syne3	45.1409	10.5761	2.0936274595444	2.111081594126	4.8366930561781	1.32E-6	4.91E-5	4.91E-5	1
468	Snhg12	45.3664	104.562	-1.2046625556362	-1.1872084210547	-4.8293049435626	1.37E-6	5.07E-5	5.07E-5	1
469	Rab32	69.2714	24.1005	1.5231967539383	1.5406508885198	4.8269552771893	1.39E-6	5.12E-5	5.12E-5	1
470	Serp1	100.143	182.316	-0.86437959720739	-0.84692546262589	-4.8256154020817	1.40E-6	5.14E-5	5.14E-5	1
471	Canx	195.787	306.456	-0.64639497605142	-0.62894084146991	-4.8252493491582	1.40E-6	5.14E-5	5.14E-5	1
472	Chac1	2.04852	25.8236	-3.6560362537358	-3.6385821191543	-4.8096400329318	1.51E-6	5.55E-5	5.55E-5	1
473	Eprs	70.5157	140.92	-0.99885997206669	-0.98140583748518	-4.8028729510479	1.56E-6	5.73E-5	5.73E-5	1
474	Mir221	21.2261	0	5.4077674153759	5.4252215499574	4.7994639280787	1.59E-6	5.81E-5	5.81E-5	1
475	Apod	22.7569	1.21124	4.2317473837097	4.2492015182912	4.7720921730658	1.82E-6	6.65E-5	6.65E-5	1
477	Cd44	97.1275	177.028	-0.86602583204041	-0.8485716974589	-4.7629916313775	1.91E-6	6.92E-5	6.92E-5	1
478	Col4a1	273.624	175.854	0.63781662578792	0.65527076036943	4.7573308514418	1.96E-6	7.11E-5	7.11E-5	1
479	Tceb1	52.7435	114.498	-1.1182571830587	-1.1008030484772	-4.7564618963602	1.97E-6	7.12E-5	7.12E-5	1
480	Mir568	20.852	0	5.3821138599339	5.3995679945154	4.755581610534	1.98E-6	7.14E-5	7.14E-5	1
481	Gzmc	3.7112	29.831	-3.0068546843462	-2.9894005497647	-4.7527673955263	2.01E-6	7.22E-5	7.22E-5	1
482	Mirlet7g	0	21.0479	-5.3956043941781	-5.3781502595966	-4.7478044564496	2.06E-6	7.39E-5	7.39E-5	1
483	Pdcd4	67.7123	23.988	1.4971050465367	1.5145591811182	4.7127624623276	2.44E-6	8.76E-5	8.76E-5	1
486	S100a13	135.698	70.1558	0.95176517158102	0.96921930616253	4.6926554113623	2.70E-6	9.61E-5	9.61E-5	1
487	Fcgrt	131.31	67.064	0.96936635014885	0.98682048473036	4.6856672581797	2.79E-6	9.92E-5	9.92E-5	1
488	Hnrnpab	100.905	180.391	-0.83812969798677	-0.82067556340526	-4.6725021803323	2.98E-6	0.00010558840509725	0.00010558840509725	1
489	Mir6240	92.5412	40.2204	1.2021683771276	1.2196225117091	4.6692763039363	3.02E-6	0.00010704052897008	0.00010704052897008	1
490	Rrm2	118.274	58.0089	1.0277867955599	1.0452409301414	4.6627945019844	3.12E-6	0.00011024363079157	0.00011024363079157	1
491	Rnf11	48.5276	106.695	-1.136615152887	-1.1191610183055	-4.6532579726375	3.27E-6	0.00011523425064513	0.00011523425064513	1
492	Hspd1	119.373	204.235	-0.77475356166515	-0.75729942708365	-4.6385026143895	3.51E-6	0.00012352177283922	0.00012352177283922	1
493	Col4a2	170.071	96.4257	0.81864753870074	0.83610167328225	4.6377717522073	3.52E-6	0.00012370779903251	0.00012370779903251	1
494	Pla1a	46.4688	12.3365	1.9133292453183	1.9307833798998	4.6306500973615	3.65E-6	0.00012778102992704	0.00012778102992704	1
495	Ccl2	14.9603	52.2192	-1.803441249695	-1.7859871151135	-4.6279850854125	3.69E-6	0.00012917453517501	0.00012917453517501	1
496	Ctsk	234.028	146.625	0.67455004140325	0.69200417598476	4.6167421554635	3.90E-6	0.00013609594525463	0.00013609594525463	1
497	Mir1951	0	19.8909	-5.3140366499007	-5.2965825153192	-4.6101709401782	4.02E-6	0.0001396249959916	0.00013906761077806	1
498	Mir3070a	0	19.8909	-5.3140366499007	-5.2965825153192	-4.6101709401782	4.02E-6	0.0001396249959916	0.00013906761077806	1
499	Mir324	0	19.8909	-5.3140366499007	-5.2965825153192	-4.6101709401782	4.02E-6	0.0001396249959916	0.00013906761077806	1
500	Mir5709	0	19.8909	-5.3140366499007	-5.2965825153192	-4.6101709401782	4.02E-6	0.0001396249959916	0.00013906761077806	1
501	Mir687	0	19.8909	-5.3140366499007	-5.2965825153192	-4.6101709401782	4.02E-6	0.0001396249959916	0.00013906761077806	1
502	Snora3	98.3545	175.686	-0.83693626443039	-0.81948212984888	-4.6054030448399	4.12E-6	0.00014200897426672	0.00014200897426672	1
503	Mir654	19.5715	0	5.2906824262037	5.3081365607852	4.6015673956295	4.19E-6	0.00014436230258116	0.00014436230258116	1
504	Herpud1	31.7059	80.2147	-1.3391153169785	-1.321661182397	-4.6003929252762	4.22E-6	0.00014489063149956	0.00014489063149956	1
505	Basp1	83.7519	155.753	-0.89506612665308	-0.87761199207157	-4.597286621886	4.28E-6	0.00014677567357289	0.00014657217064036	1
506	C1s1	32.2591	5.49823	2.5526670256242	2.5701211602057	4.5971634854324	4.28E-6	0.00014657217064036	0.00014657217064036	1
507	Hist1h2bn	59.2354	121.414	-1.0354032696207	-1.0179491350392	-4.5948670932194	4.33E-6	0.00014790329426811	0.00014790329426811	1
508	Prrg3	19.4446	0	6.1192887559971	6.1367428905786	4.5933554276227	4.36E-6	0.00014868595414929	0.00014868595414929	1
510	Mir677	117.517	200.654	-0.77184044422223	-0.75438630964072	-4.5822779520426	4.60E-6	0.00015617149217961	0.00015617149217961	1
511	Ran	117.308	200.333	-0.77209868618742	-0.75464455160591	-4.5799729447557	4.65E-6	0.00015759353882773	0.0001573167947389	1
513	Ass1	139.114	74.0359	0.90997070733596	0.92742484191747	4.579523532148	4.66E-6	0.0001573167947389	0.0001573167947389	1
514	Scarna3b	56.1383	18.0429	1.6375541375265	1.655008272108	4.5762893787236	4.73E-6	0.00015945646854822	0.00015945646854822	1
515	Aldh1l2	4.88706	31.1861	-2.6738644244991	-2.6564102899176	-4.5747216428224	4.77E-6	0.00016034316431801	0.00016034316431801	1
516	Snx1	100.505	46.6365	1.1077358498961	1.1251899844776	4.5633604804405	5.03E-6	0.00016894568687988	0.00016894568687988	1
518	Klf15	20.4744	1.03113	4.3115230370073	4.3289771715888	4.5481204976113	5.41E-6	0.00018094975543692	0.00018094975543692	1
520	Cct2	155.505	248.564	-0.67665639471713	-0.65920226013562	-4.5308005688495	5.88E-6	0.00019568406148145	0.00019568406148145	1
521	Rgcc	44.4892	11.8276	1.9112977977601	1.9287519323416	4.5277663102022	5.96E-6	0.00019813324186431	0.00019813324186431	1
523	Sdc2	64.0684	127.083	-0.98808618552411	-0.9706320509426	-4.5193199617697	6.20E-6	0.00020541530606226	0.00020541530606226	1
524	Ghr	74.0868	29.4915	1.3289173185472	1.3463714531288	4.5117988925228	6.43E-6	0.00021243107912495	0.00021243107912495	1
525	Procr	50.9165	15.452	1.720339669114	1.7377938036955	4.5110753183931	6.45E-6	0.00021275109261792	0.00021275109261792	1
528	Sulf2	76.7449	31.3576	1.2912557360237	1.3087098706052	4.4928034549299	7.03E-6	0.00023053798358957	0.00023053798358957	1
529	Mir541	0	18.8196	-5.234164059609	-5.2167099250275	-4.4782356527343	7.53E-6	0.00024637440535243	0.00024637440535243	1
530	Selenbp1	19.3466	0	4.4834529418329	4.5009070764144	4.4617405748319	8.13E-6	0.00026562516785033	0.00026562516785033	1
531	Arhgef2	13.0521	46.8963	-1.8451921562837	-1.8277380217022	-4.4559359096815	8.35E-6	0.00027240190575384	0.00027192789342221	1
532	Tns1	44.7732	12.3623	1.8566882523184	1.8741423868999	4.4555559100924	8.37E-6	0.00027237194669567	0.00027192789342221	1
533	Hexa	193.145	116.932	0.72401453396787	0.74146866854938	4.4555030772533	8.37E-6	0.00027192789342221	0.00027192789342221	1
534	Mir196b	18.3975	0	5.201437829504	5.2188919640855	4.4547738231841	8.40E-6	0.00027234284375954	0.00027234284375954	1
535	Gclc	63.2153	23.1627	1.4484703428064	1.4659244773879	4.4446530506091	8.80E-6	0.00028494983997495	0.00028494983997495	1
536	Mir1291	12.623	45.971	-1.8646692252057	-1.8472150906241	-4.4437456663241	8.84E-6	0.00028562099187326	0.00028562099187326	1
538	Eif4ebp1	85.1554	154.786	-0.86210506506007	-0.84465093047856	-4.4361337539336	9.16E-6	0.00029480406901165	0.00029480406901165	1
539	Psph	11.7691	44.1558	-1.9075989531168	-1.8901448185353	-4.4233124981436	9.72E-6	0.00031228106090595	0.00031228106090595	1
540	Mfap5	217.444	136.826	0.66830150002137	0.68575563460288	4.4147218599616	1.01E-5	0.00032434081545889	0.00032434081545889	1
541	Pamr1	41.9218	11.0552	1.9229755380933	1.9404296726748	4.4128486292639	1.02E-5	0.00032655613560764	0.00032603357806134	1
543	Myl12b	91.3184	41.8279	1.1264400139101	1.1438941484916	4.4077898220509	1.04E-5	0.00033304389154954	0.00033304389154954	1
544	Scara3	56.1498	19.1364	1.5529614328965	1.570415567478	4.4069572698245	1.05E-5	0.00033371151081794	0.00033371151081794	1
545	Ghitm	62.507	122.924	-0.97567695104245	-0.95822281646094	-4.397368541302	1.10E-5	0.0003481549715939	0.0003481549715939	1
546	Sesn1	31.2768	5.86191	2.4156501917125	2.433104326294	4.3882737480105	1.14E-5	0.00036236903862347	0.00036212093047207	1
547	Matn2	33.3468	6.83406	2.2867335061043	2.3041876406858	4.3880246869172	1.14E-5	0.00036212093047207	0.00036212093047207	1
550	Bst2	86.7485	39.1846	1.1465520418105	1.164006176392	4.3564001189839	1.32E-5	0.00041629748497263	0.00041629748497263	1
551	Mir3061	0	17.8259	-5.155903012665	-5.1384488780835	-4.3516358398914	1.35E-5	0.00042429181394048	0.00042390749164524	1
552	Mir431	0	17.8259	-5.155903012665	-5.1384488780835	-4.3516358398914	1.35E-5	0.00042429181394048	0.00042390749164524	1
554	C4b	17.6514	0	4.9475782576834	4.9650323922649	4.3379493964757	1.44E-5	0.00044954886945123	0.00044954886945123	1
555	Mir181b-2	17.3187	0	5.1142587354634	5.1317128700449	4.3146820634153	1.60E-5	0.00049870702307847	0.00049870702307847	1
556	Hnrnph1	47.0444	99.5026	-1.0807112238995	-1.063257089318	-4.3107653371824	1.63E-5	0.00050671062751268	0.00050671062751268	1
557	Hist1h1a	25.838	67.1667	-1.3782517468896	-1.360797612308	-4.3049784767611	1.67E-5	0.00051920523120506	0.00051920523120506	1
558	Zfp36l2	75.3349	31.9827	1.2360266322466	1.2534807668282	4.304487724264	1.67E-5	0.00051942488039015	0.00051942488039015	1
559	Tmeff1	14.9238	48.7193	-1.7068784734728	-1.6894243388913	-4.2998631155578	1.71E-5	0.00052943440012172	0.00052943440012172	1
561	Lrrc59	75.0085	138.479	-0.88454121480995	-0.86708708022844	-4.2906657836109	1.78E-5	0.00054987877583045	0.00054987877583045	1
563	Flot1	83.2624	37.456	1.1524683045293	1.1699224391108	4.2852602513585	1.83E-5	0.00056141957360858	0.00056072729851529	1
564	Sulf1	63.7999	122.947	-0.94641046468733	-0.92895633010582	-4.2851400289822	1.83E-5	0.00056072729851529	0.00056072729851529	1
565	Crabp2	12.3406	43.7923	-1.827264683031	-1.8098105484494	-4.2769730969104	1.89E-5	0.00058066104038343	0.00058022225363147	1
567	Cthrc1	53.5395	108.311	-1.0165041986569	-0.99905006407536	-4.273230223952	1.93E-5	0.00058841562377202	0.00058841562377202	1
568	Ehbp1	34.4719	7.88452	2.1283259851533	2.1457801197348	4.2703517085559	1.95E-5	0.00059501258238888	0.00059501258238888	1
569	Prnp	216.358	138.419	0.64437847925568	0.66183261383719	4.2677150224627	1.97E-5	0.0006010288947763	0.0006010288947763	1
570	Ube2s	84.8506	151.355	-0.83493956868763	-0.81748543410612	-4.265638004006	1.99E-5	0.00060558385839853	0.00060558385839853	1
571	Pam	178.828	108.649	0.71889774814427	0.73635188272578	4.261356694149	2.03E-5	0.00061622325766641	0.00061622325766641	1
572	Mab21l1	21.7417	2.26686	3.2616975512868	3.2791516858683	4.2585047981303	2.06E-5	0.00062304508326674	0.00062304508326674	1
573	Prune2	23.932	3.13504	2.9323852124908	2.9498393470723	4.2552036976636	2.09E-5	0.00063120550847333	0.00063120550847333	1
574	Pros1	128.793	70.414	0.8711199789486	0.88857411353011	4.2502872011266	2.13E-5	0.00064409762651144	0.00064409762651144	1
577	Dap	113.878	59.4663	0.9373448418919	0.95479897647341	4.2454467163767	2.18E-5	0.00065473970956911	0.00065473970956911	1
578	Crispld2	25.0788	3.66316	2.7753076962524	2.7927618308339	4.2378077160973	2.26E-5	0.00067624067363519	0.00067624067363519	1
579	Kitl	26.788	4.39853	2.6064935161303	2.6239476507118	4.2372502487365	2.26E-5	0.00067675043538307	0.00067675043538307	1
580	Bag2	8.95272	36.9268	-2.0442702757817	-2.0268161412002	-4.2360124656576	2.28E-5	0.00067931650473396	0.00067931650473396	1
581	Mir674	16.7256	0	5.0639860607017	5.0814401952832	4.2353554245781	2.28E-5	0.0006801333188153	0.0006801333188153	1
582	Mir615	0	16.9029	-5.079198883211	-5.0617447486295	-4.2300759630079	2.34E-5	0.00069450062349	0.00069390499688324	1
583	Mir667	0	16.9029	-5.079198883211	-5.0617447486295	-4.2300759630079	2.34E-5	0.00069450062349	0.00069390499688324	1
584	H2afz	99.9115	170.628	-0.7721317622983	-0.75467762771679	-4.226910200345	2.37E-5	0.00070253101081766	0.00070253101081766	1
586	S100a7a	21.9554	2.49918	3.1350491004037	3.1525032349852	4.2053915648227	2.61E-5	0.00077019433899882	0.00077019433899882	1
588	Slc44a2	93.9053	45.7037	1.0388956204661	1.0563497550476	4.1908095396724	2.78E-5	0.00081861381725451	0.00081861381725451	1
589	Rgs2	24.334	3.52251	2.7882977813232	2.8057519159048	4.1843915185592	2.86E-5	0.00084065640718615	0.00084065640718615	1
591	Mir365-1	16.3254	0	5.0290464355685	5.04650057015	4.1808433220533	2.90E-5	0.00085099411916645	0.00085099411916645	1
592	Mir8091	29.1555	5.6893	2.3574450020858	2.3748991366673	4.1774134675855	2.95E-5	0.00086246492347885	0.00086246492347885	1
593	Ptgis	64.9925	26.2979	1.3053256449879	1.3227797795694	4.1687684262253	3.06E-5	0.00089432214022943	0.00089432214022943	1
595	Cyb5r3	185.591	115.498	0.68425888080406	0.70171301538557	4.1618957511976	3.16E-5	0.00091857644972651	0.00091857644972651	1
596	Medag	120.552	65.3363	0.88369892369219	0.9011530582737	4.1611759456113	3.17E-5	0.00091993084532742	0.00091993084532742	1
597	Aldh6a1	34.3809	8.33555	2.0442580111911	2.0617121457726	4.157759041986	3.21E-5	0.00093223110742018	0.00093223110742018	1
598	Ablim1	26.616	4.65842	2.5143811483978	2.5318352829793	4.1409296873979	3.46E-5	0.0010016667933227	0.0010016667933227	1
599	Fmo3	18.362	0	8.3496954816949	8.3671496162764	4.1349951318115	3.55E-5	0.0010261902711167	0.0010261902711167	1
600	Penk	16.6836	0	4.429543241531	4.4469973761125	4.1320987519268	3.59E-5	0.0010374785367462	0.0010374785367462	1
603	Snora15	87.2328	41.7046	1.0646641769658	1.0821183115473	4.1192608164756	3.80E-5	0.0010915445939587	0.0010915445939587	1
604	Hif1a	85.7248	149.936	-0.80656228108045	-0.78910814649894	-4.1184205245873	3.81E-5	0.0010937178870682	0.0010937178870682	1
605	Spsb1	34.2692	8.51742	2.0084241161815	2.0258782507631	4.1042593637998	4.06E-5	0.0011609895392341	0.0011609895392341	1
606	Acvrl1	29.0174	5.91366	2.2947950530447	2.3122491876262	4.10186025116	4.10E-5	0.0011711601135222	0.0011711601135222	1
607	Layn	52.6877	19.0589	1.4670013471403	1.4844554817218	4.0958196372057	4.21E-5	0.0012001433040929	0.0012001433040929	1
608	Ehd3	46.4177	15.3449	1.5969157947754	1.6143699293569	4.0877627632737	4.36E-5	0.0012405386653571	0.0012405386653571	1
609	Tmem176b	38.9028	11.1345	1.8048372211718	1.8222913557533	4.0747412322278	4.61E-5	0.0013098800711098	0.0013098800711098	1
610	Ppbp	0	15.7368	-4.9970722577739	-4.9796181231924	-4.0728853180203	4.64E-5	0.0013182010228572	0.0013182010228572	1
611	Ctdsp2	61.7317	24.9174	1.3088579830477	1.3263121176292	4.0711970629682	4.68E-5	0.0013256194648234	0.0013256194648234	1
612	Mcfd2	100.251	168.102	-0.74572026161444	-0.72826612703293	-4.0672459360686	4.76E-5	0.0013460863232163	0.0013460863232163	1
613	Cd248	120.031	66.0791	0.86114111148173	0.87859524606324	4.0640925272287	4.82E-5	0.0013621867497517	0.0013621867497517	1
614	Lima1	67.7844	124.731	-0.87979487697532	-0.86234074239381	-4.0531341342816	5.05E-5	0.0014252964785326	0.0014247912243497	1
615	Mir3101	15.409	0	4.9457013329988	4.9631554675803	4.0528364861821	5.06E-5	0.0014247912243497	0.0014247912243497	1
616	Hspb7	21.902	2.93383	2.9002054348175	2.917659569399	4.0488400095935	5.15E-5	0.0014469847675325	0.0014469847675325	1
618	Slc7a5	5.58194	28.3114	-2.3425445702006	-2.3250904356191	-4.0405814480512	5.33E-5	0.001494049206991	0.0014929719481458	1
619	Kpna2	55.2108	107.198	-0.95725557866464	-0.93980144408313	-4.0403714390851	5.34E-5	0.0014929719481458	0.0014929719481458	1
620	Itgav	42.4843	89.0385	-1.067499494047	-1.0500453594655	-4.0363471938844	5.43E-5	0.001516350738745	0.001516350738745	1
621	Map1lc3b	158.654	96.3579	0.71940903778472	0.73686317236623	4.0161961395174	5.91E-5	0.0016492988803084	0.0016492988803084	1
622	Cyb561	14.9954	0	5.1243717299616	5.1418258645431	4.0157255565188	5.93E-5	0.0016499367041806	0.0016499367041806	1
623	Prg4	30.8316	7.15199	2.1079931353303	2.1254472699118	4.0144310111925	5.96E-5	0.001656354910803	0.001656354910803	1
624	Slit3	33.2612	8.4002	1.985344636744	2.0027987713255	4.0134010773197	5.99E-5	0.0016609359402449	0.0016600250034501	1
625	Mir763	15.1315	0	4.919483105264	4.9369372398455	4.0131527014388	5.99E-5	0.0016600250034501	0.0016600250034501	1
626	Fxyd1	21.7937	3.00417	2.8588727896004	2.8763269241819	4.0102223327588	6.07E-5	0.0016780781560614	0.0016780781560614	1
627	Odc1	70.176	127.251	-0.85862737150523	-0.84117323692372	-4.0080629105525	6.12E-5	0.0016907914064951	0.0016907914064951	1
628	Man1a	39.1013	11.6024	1.7527933104699	1.7702474450514	4.0044066333794	6.22E-5	0.0017144199566295	0.0017144199566295	1
629	Cd24a	45.6499	15.3871	1.5688903466834	1.5863444812649	4.0028315487092	6.26E-5	0.0017231341949936	0.0017218384523882	1
630	Srsf5	145.872	224.835	-0.62416365115793	-0.60670951657642	-4.0021811437331	6.28E-5	0.0017251365147461	0.0017218384523882	1
631	Sec13	147.382	226.709	-0.62128132846559	-0.60382719388408	-4.0017351077293	6.29E-5	0.0017256533782188	0.0017218384523882	1
633	Col18a1	26.8632	5.27244	2.3490884943664	2.3665426289479	4.0015100393947	6.29E-5	0.0017218384523882	0.0017218384523882	1
634	Lama2	31.468	7.5684	2.0558252445612	2.0732793791427	3.9920336481294	6.55E-5	0.0017893070106928	0.0017893070106928	1
635	Mir453	89.007	151.974	-0.77183381865117	-0.75437968406966	-3.9877699795218	6.67E-5	0.0018188926870923	0.0018188926870923	1
636	Sh3bgrl3	171.478	106.928	0.68138381136282	0.69883794594433	3.9860953247853	6.72E-5	0.0018288912546041	0.0018288912546041	1
637	Actr3	104.338	171.835	-0.71975923548247	-0.70230510090096	-3.9834579779123	6.79E-5	0.0018464131903173	0.0018464131903173	1
638	Il6	0	16.4179	-4.0696837724053	-4.0522296378238	-3.9755205857054	7.02E-5	0.0019061041398593	0.0019061041398593	1
639	Shmt2	14.7513	45.1125	-1.6126851364678	-1.5952310018863	-3.9712376127989	7.15E-5	0.0019376671775303	0.0019376671775303	1
641	Gdf15	8.55897	33.7565	-1.9796562318094	-1.9622020972279	-3.9651250853646	7.34E-5	0.0019817960740272	0.0019817960740272	1
643	11-Sep	57.985	109.857	-0.9218751537509	-0.90442101916939	-3.9604056963511	7.48E-5	0.002015088457804	0.002015088457804	1
644	Mir210	0	14.9567	-4.9027199934544	-4.8852658588729	-3.9596311154072	7.51E-5	0.0020184959493711	0.0020184959493711	1
646	Mir1247	111.259	60.7897	0.87202323961858	0.88947737420009	3.9537567270214	7.69E-5	0.0020623215419725	0.0020623215419725	1
648	Actn1	81.5632	141.387	-0.79365919251185	-0.77620505793034	-3.9426848040393	8.06E-5	0.002153254556594	0.002153254556594	1
649	Sepw1	213.762	141.895	0.59118165754849	0.60863579213	3.93719774562	8.24E-5	0.0021996771323612	0.0021996771323612	1
650	Has2	12.9752	41.6469	-1.6824523356461	-1.6649982010646	-3.9346657886088	8.33E-5	0.0022195743606394	0.0022195743606394	1
654	Hsd17b11	47.0922	16.7138	1.4944483448448	1.5119024794263	3.9251011158173	8.67E-5	0.0022955170078355	0.0022955170078355	1
655	Lmcd1	34.3198	9.36519	1.8736609763745	1.891115110956	3.9246591642306	8.69E-5	0.0022962241413331	0.0022962241413331	1
656	Il34	27.635	5.93384	2.2194586809109	2.2369128154924	3.9234247397098	8.73E-5	0.0023045084783773	0.0023045084783773	1
657	Nop56	32.0217	72.1147	-1.1712434700693	-1.1537893354878	-3.9202998732197	8.84E-5	0.0023310435430035	0.0023310435430035	1
658	Hacd1	33.6851	74.5195	-1.1455074121093	-1.1280532775278	-3.9136569719003	9.09E-5	0.0023925029312436	0.0023925029312436	1
659	Fam20a	13.1261	41.7054	-1.6677958660961	-1.6503417315146	-3.9126933513278	9.13E-5	0.0023984283122404	0.0023984283122404	1
662	Mir374b	0	14.497	-4.857682475616	-4.8402283410345	-3.8926284681768	9.92E-5	0.0025939913148328	0.0025909544932361	1
663	Marcksl1	16.2482	46.8918	-1.5290557566935	-1.5116016221119	-3.8925464868735	9.92E-5	0.0025909544932361	0.0025909544932361	1
664	Clec3b	15.1499	0	7.6125912437348	7.6300453783163	3.8917247570304	9.95E-5	0.0025958319816741	0.0025958319816741	1
665	Mir29c	0	14.4837	-4.8563582946686	-4.8389041600871	-3.8906706596155	1.00E-4	0.0026032148535294	0.0026032148535294	1
666	Sars	47.6087	94.2932	-0.98592849869966	-0.96847436411816	-3.8856168615343	0.00010207037768096	0.0026539830785304	0.0026539830785304	1
668	Stbd1	3.40973	22.2032	-2.7030382087771	-2.6855840741956	-3.8827472675148	0.00010328290171755	0.0026774700734173	0.0026774700734173	1
669	Tmem176a	32.282	8.50843	1.9237651108173	1.9412192453988	3.8734270613443	0.00010731553451815	0.0027778521842314	0.0027778521842314	1
670	Sfrp1	71.8789	33.2562	1.11194500136	1.1293991359415	3.8707211087565	0.00010851388180176	0.0028046789420314	0.0028011946539803	1
671	Pdlim7	18.9223	51.1072	-1.4334390943635	-1.415984959782	-3.8702977960777	0.00010870248652612	0.0028053665561444	0.0028011946539803	1
674	Il1r1	29.3262	7.00124	2.0665077755013	2.0839619100828	3.8664755425861	0.00011041953168592	0.0028369955937762	0.0028369955937762	1
675	Grina	70.7831	32.5929	1.1188472234325	1.136301358014	3.8599562989631	0.00011340730476272	0.0029094434023348	0.0029083763695583	1
676	Cct3	121.34	191.133	-0.65552167133562	-0.63806753675411	-3.8596841755422	0.00011353366205586	0.0029083763695583	0.0029083763695583	1
677	Anxa8	166.535	104.854	0.66744351583157	0.68489765041308	3.8591688319712	0.00011377331969888	0.0029102106015149	0.0029102106015149	1
678	Pdpn	199.217	131.295	0.60152878741461	0.61898292199612	3.8585553363419	0.00011405924454251	0.0029132211471131	0.0029132211471131	1
679	Mrgprf	39.8287	12.783	1.6395819338721	1.6570360684536	3.85797071762	0.00011433234158767	0.0029158956690333	0.002915871167546	1
680	1500009L16Rik	23.876	4.39503	2.4416162407049	2.4590703752864	3.8576129697923	0.00011449976288799	0.002915871167546	0.002915871167546	1
681	Colec12	119.962	68.5615	0.80710690162129	0.8245610362028	3.8489258644169	0.00011863690258083	0.0030167918384615	0.0030167918384615	1
682	Mir6391	14.0116	0	4.8085498029949	4.8260039375764	3.8482844279109	0.0001189479027883	0.0030202651504179	0.0030202651504179	1
683	Abi3bp	18.0039	1.94716	3.2088661149487	3.2263202495302	3.8478254110495	0.00011917092863304	0.0030214977615495	0.0030214977615495	1
684	Tmem158	16.218	1.28982	3.6523542672759	3.6698084018575	3.8467193455274	0.00011970996156982	0.003030727199568	0.003030727199568	1
685	Slirp	134.29	207.085	-0.62487117967803	-0.60741704509652	-3.8449319361868	0.0001205859044529	0.0030484468721327	0.0030484468721327	1
686	Nnmt	95.2474	50.1274	0.92608030483225	0.94353443941375	3.8443285572942	0.00012088295984109	0.0030515017719652	0.0030515017719652	1
689	Pck2	24.3932	59.1847	-1.2787452397792	-1.2612911051977	-3.8107306165483	0.00013855668763095	0.0034824182288899	0.0034824182288899	1
690	Rab9	63.044	27.7353	1.1846357429365	1.202089877518	3.8100471797861	0.00013894027466552	0.0034869981686707	0.0034869981686707	1
691	Ranbp1	105.281	169.759	-0.68924296537002	-0.67178883078851	-3.8073632651958	0.00014045635251985	0.0035199459574331	0.0035199459574331	1
692	Ccdc152	13.3324	0	5.4354548889814	5.4529090235629	3.8048592079223	0.00014188487174816	0.0035506074047152	0.0035506074047152	1
693	Psd3	32.6865	9.03879	1.8544933439628	1.8719474785444	3.8039238241716	0.00014242199301269	0.0035589057041859	0.0035589057041859	1
695	Nop58	38.4619	80.0277	-1.0570694137929	-1.0396152792114	-3.7954903075824	0.0001473519521151	0.0036715018054348	0.0036715018054348	1
696	Lars	41.8204	84.8377	-1.0204986481334	-1.0030445135519	-3.7943981401833	0.00014800202416431	0.0036824009374329	0.0036824009374329	1
697	Slco3a1	28.3539	6.80363	2.0591705969554	2.0766247315369	3.7932729368644	0.00014867458301127	0.0036938274806402	0.0036902510733349	1
698	Eif3c	93.5379	154.43	-0.72333009718485	-0.70587596260334	-3.793157517104	0.00014874373443366	0.0036902510733349	0.0036902510733349	1
699	Itga10	13.4558	0	4.958000568055	4.9754547026365	3.7885743878537	0.00015151422748401	0.0037536078359666	0.0037536078359666	1
700	Cars	17.7661	48.3369	-1.4439979345571	-1.4265437999756	-3.7850720682175	0.00015366404113903	0.0038014288577209	0.0038014288577209	1
701	Hist1h1b	25.8111	61.0359	-1.241666427891	-1.2242122933095	-3.7803190986498	0.00015662748811579	0.0038692128554938	0.0038692128554938	1
702	Ypel3	55.5632	23.0305	1.2705839566419	1.2880380912234	3.7759322894976	0.00015941029421876	0.0039323476709205	0.0039323476709205	1
703	Bhlhe40	6.54905	28.165	-2.1045459208361	-2.0870917862546	-3.7699118027593	0.00016330524732954	0.0040226983897662	0.0040226983897662	1
704	Anxa6	140.871	213.687	-0.60112449596085	-0.58367036137934	-3.768536713785	0.00016420733609866	0.0040391739193473	0.0040391739193473	1
705	Ier5	13.5585	41.0522	-1.5982619590576	-1.5808078244761	-3.7634493367099	0.00016758569073716	0.0041164275269438	0.0041164275269438	1
706	Ero1l	16.3175	45.6297	-1.4835531292759	-1.4660989946944	-3.7536990371168	0.00017424405585259	0.0042739154606222	0.0042739154606222	1
707	M6pr	58.5109	107.478	-0.87726406576735	-0.85980993118584	-3.752965792657	0.00017475470934509	0.0042803780788244	0.0042803780788244	1
708	Ankrd29	16.2785	1.53877	3.4031182538126	3.4205723883942	3.7506921612007	0.00017634709725621	0.0043132806259686	0.0043132806259686	1
709	Lama4	71.9281	34.4066	1.0638701609135	1.081324295495	3.7382398857328	0.00018531308720538	0.004526187208936	0.004526187208936	1
710	Adamtsl3	10.5514	35.5007	-1.7504130379307	-1.7329589033491	-3.7367495936869	0.00018641440093461	0.0045466734943445	0.0045466734943445	1
711	Plxna2	27.4209	6.5564	2.0643001438218	2.0817542784033	3.7362320152302	0.00018679832447762	0.0045496295147382	0.0045496295147382	1
712	Avpi1	28.5176	64.6068	-1.1798334478018	-1.1623793132203	-3.7326751019555	0.00018945690454584	0.0046079005842983	0.0046079005842983	1
713	Acot7	23.4404	56.8228	-1.277472734593	-1.2600186000115	-3.7309710168817	0.00019074316890295	0.0046326780587552	0.0046279184135412	1
714	Angpt1	33.0633	9.58255	1.7867491992374	1.8042033338189	3.7308769038533	0.00019081444518498	0.0046279184135412	0.0046279184135412	1
715	Aldh18a1	28.5237	64.5755	-1.1788257734449	-1.1613716388634	-3.7291868221435	0.0001920986933872	0.0046525497529876	0.0046525497529876	1
716	Ehd2	139.607	85.3041	0.71068429211024	0.72813842669175	3.728406803313	0.000192694144612	0.0046604532154275	0.0046604532154275	1
717	Plod2	43.2463	85.9618	-0.99111898628337	-0.97366485170186	-3.7265063226505	0.00019415220417723	0.0046891683678342	0.0046891683678342	1
718	Coro1c	27.2668	62.5261	-1.1973131362911	-1.1798590017096	-3.7160206761594	0.00020238502816125	0.0048811999062234	0.0048811999062234	1
719	Mir3057	13.1482	0	4.7167934017189	4.7342475363004	3.715566825259	0.00020274867063431	0.0048831693037195	0.0048831693037195	1
720	Clu	12.8428	0	5.0305289568585	5.04798309144	3.7083241324663	0.00020863548682693	0.0050179732296971	0.0050142620420935	1
721	Zbtb16	18.621	0	10.13481180318	10.152265937762	3.7081599914542	0.00020877074160359	0.0050142620420935	0.0050142620420935	1
722	Slc10a6	13.9383	0	7.7773055034448	7.7947596380263	3.7061392094826	0.00021044265976265	0.0050474176441964	0.0050474176441964	1
724	Vwa5a	71.2882	34.2637	1.0569823432108	1.0744364777923	3.7022842923922	0.00021366700194485	0.005110595956739	0.005110595956739	1
726	Set	90.0799	148.353	-0.71975697038805	-0.70230283580654	-3.7012384494116	0.00021454973637867	0.0051175727064317	0.0051175727064317	1
727	Mir3074-1	91.9873	150.781	-0.71294804733936	-0.69549391275785	-3.6995938724465	0.00021594475625269	0.0051437625089792	0.0051437625089792	1
728	Vdac3	102.785	164.499	-0.67844907455595	-0.66099493997444	-3.6945909373885	0.00022024106303022	0.0052388935281515	0.0052388935281515	1
729	F3	36.436	75.7918	-1.0566771834847	-1.0392230489032	-3.6925278252535	0.00022203603840793	0.0052743457847876	0.0052743457847876	1
730	Coq10b	18.2545	48.1887	-1.4004427284502	-1.3829885938687	-3.6916352804882	0.00022281682972829	0.0052856425211025	0.0052856425211025	1
731	Phka2	21.2204	3.73849	2.5049242718729	2.5223784064544	3.6896843574815	0.00022453246524473	0.0053190543100451	0.0053190543100451	1
732	Cyp4v3	31.8314	9.1137	1.804341824015	1.8217959585965	3.6851552400933	0.00022856328347557	0.0054071453277956	0.0054071453277956	1
733	Tubb4b	134.727	204.275	-0.60047364856974	-0.58301951398823	-3.6808994551986	0.00023241264538078	0.0054907091133136	0.0054907091133136	1
734	Srsf3	48.3325	92.4549	-0.93575616264154	-0.91830202806003	-3.6800860776126	0.00023315523696409	0.005500748281345	0.005500748281345	1
735	Slc48a1	32.0754	69.24	-1.1101384679814	-1.0926843333999	-3.6766518292599	0.00023631522767097	0.0055677153708547	0.0055677153708547	1
736	Klf9	52.3533	21.6331	1.2750400610527	1.2924941956342	3.6750787187214	0.00023777609066696	0.0055945225028257	0.0055945225028257	1
737	Nradd	14.6214	42.0199	-1.5229912726056	-1.5055371380241	-3.6738610222241	0.00023891271327573	0.0056136383389359	0.0056136383389359	1
738	Tes	21.3948	52.9708	-1.3079371047169	-1.2904829701353	-3.6699556047222	0.00024259259724046	0.0056923794124838	0.0056923794124838	1
739	Snora81	34.0707	72.0605	-1.0806770734555	-1.063222938874	-3.6683434727155	0.00024412708042685	0.0057206341701647	0.0057206341701647	1
740	Cog4	71.4132	34.6657	1.0426818733578	1.0601360079393	3.6652814081868	0.00024706676245793	0.0057816961155188	0.0057816961155188	1
741	Mir1957b	75.117	37.3112	1.0095306854746	1.0269848200561	3.6625642879638	0.00024970305873771	0.0058355031958986	0.0058214531365114	1
742	Xpot	22.7638	55.0301	-1.2734795410225	-1.256025406441	-3.6625405208888	0.00024972623480326	0.0058281795257252	0.0058214531365114	1
743	Tfrc	6.2378	26.6969	-2.0975630262373	-2.0801088916558	-3.6624913474556	0.00024977419185933	0.0058214531365114	0.0058214531365114	1
744	Ehbp1l1	17.7906	47.0675	-1.4036160587265	-1.386161924145	-3.6547958977534	0.00025738665746955	0.0059908128325272	0.0059908128325272	1
745	Iars	21.9348	53.6482	-1.2903082145855	-1.272854080004	-3.6540401904912	0.00025814583274601	0.0060004179673325	0.0060004179673325	1
747	Paics	139.987	86.6163	0.69258240537202	0.71003653995353	3.6521014224775	0.00026010311210747	0.0060297263619344	0.0060297263619344	1
748	Slc2a1	8.43504	30.8738	-1.8719162481702	-1.8544621135887	-3.6513671105077	0.00026084806172769	0.0060389116108802	0.0060389116108802	1
749	Ifi205	13.6167	0	4.0492334066766	4.0666875412581	3.6463368226614	0.00026600526164599	0.0061500842669207	0.0061500842669207	1
750	Lgmn	118.129	69.6128	0.76293867165399	0.7803928062355	3.6425908987548	0.00026990761963034	0.0062319869988514	0.0062319869988514	1
751	Rad23b	75.9614	128.988	-0.76389845490523	-0.74644432032372	-3.6401616383295	0.00027246694382096	0.0062827031506624	0.0062827031506624	1
752	Hn1	50.1616	94.3648	-0.91166543879603	-0.89421130421452	-3.6355163391633	0.00027742440845833	0.0063885086187139	0.0063885086187139	1
753	Ext1	45.7194	88.1816	-0.9476711835683	-0.93021704898679	-3.6331494850543	0.00027998270240996	0.0064388585094732	0.0064388585094732	1
756	Nkain4	20.2428	3.5066	2.5292640825603	2.5467182171419	3.623151655384	0.00029103506640281	0.006666473868912	0.006666473868912	1
757	Pdcl3	24.1003	56.5676	-1.2309248576906	-1.2134707231091	-3.6140982986342	0.00030139470620824	0.0068946527442643	0.0068946527442643	1
758	Rnu11	100.811	56.7013	0.83019934964194	0.84765348422345	3.6126490849016	0.00030308474489321	0.0069241669225801	0.0069241669225801	1
759	Cnbp	123.079	188.439	-0.61451295397433	-0.59705881939282	-3.6116529298772	0.00030425157946461	0.0069416661417505	0.0069416661417505	1
761	Plekhf1	58.4174	26.1383	1.1602328359208	1.1776869705023	3.6083476525646	0.00030815338236649	0.0070122104105657	0.0070122104105657	1
763	Dcxr	91.3152	49.6936	0.87779496584823	0.89524910042973	3.6015133866155	0.00031637012875339	0.007180316539479	0.007180316539479	1
764	Olfml3	118.443	70.3632	0.75129993683424	0.76875407141575	3.6002864035312	0.00031786685920364	0.007204843456583	0.007204843456583	1
765	Hes1	10.0862	33.4567	-1.7299124142402	-1.7124582796587	-3.5974222734524	0.00032138649107893	0.0072750978640704	0.0072750978640704	1
766	Ifngr1	65.1601	30.9524	1.0739375398808	1.0913916744623	3.5848801211418	0.00033723306932016	0.0076238447276987	0.0076238447276987	1
767	Smim3	10.0731	33.2576	-1.7231763202251	-1.7057221856436	-3.5767661393427	0.00034787112716091	0.0078540864524713	0.0078540864524713	1
768	Galnt1	130.617	80.1951	0.70375668365452	0.72121081823603	3.5763300338656	0.00034845169116146	0.0078569504372956	0.0078569504372956	1
769	Atraid	97.8356	54.8654	0.83446289932241	0.85191703390392	3.5741914387375	0.00035131183133879	0.0079111404204081	0.0079111404204081	1
770	Naaa	41.8502	15.5984	1.4238364645824	1.4412905991639	3.5708070872491	0.00035588294265641	0.0080036687246507	0.0080036687246507	1
771	Glud1	140.725	88.3213	0.67204533581226	0.68949947039377	3.5684838347435	0.000359053002147	0.0080644887654729	0.0080644887654729	1
772	Arl5a	28.1265	61.8917	-1.137815911463	-1.1203617768815	-3.5470682466378	0.00038954366741942	0.0087379892340701	0.0087378479943113	1
774	Atp6v1g1	90.1815	145.78	-0.69288939372388	-0.67543525914237	-3.5451036936569	0.00039245866113127	0.0087806287271451	0.0087806287271451	1
775	Mir669k	20.9576	4.08958	2.3574489222689	2.3749030568504	3.5417472111605	0.00039748620180058	0.0088816368472009	0.0088808665242927	1
776	Osr1	32.4782	10.1486	1.6781909567301	1.6956450913116	3.5412222034708	0.0003982780106432	0.0088878612246242	0.0088808665242927	1
777	Serpinb8	17.062	2.37088	2.8472922195918	2.8647463541733	3.5410901464836	0.00039847740886848	0.0088808665242927	0.0088808665242927	1
778	Gm20319	26.5555	6.89786	1.9447899404036	1.9622440749851	3.5382446251298	0.00040279670094822	0.0089655918641649	0.0089655918641649	1
779	Vcan	152.823	98.5051	0.6335913609616	0.65104549554311	3.5348130493821	0.00040806375404398	0.0090711682012575	0.0090711682012575	1
780	Svep1	73.2214	37.1083	0.98052344835439	0.9979775829359	3.5316262466875	0.00041301265918813	0.0091694105373856	0.0091694105373856	1
781	Ror1	16.471	2.16216	2.9293829560572	2.9468370906387	3.5283683200899	0.00041812992136332	0.0092711342487179	0.0092711342487179	1
783	Srxn1	19.8261	49.0258	-1.3061402600572	-1.2886861254757	-3.5268290229715	0.00042056825472646	0.0093013799068941	0.0093013799068941	1
784	Slc44a1	35.3354	11.9148	1.5683595056621	1.5858136402436	3.520834377882	0.00043019122214858	0.0095020681045242	0.0095020681045242	1
785	Gadd45a	4.37791	21.7673	-2.3138482664185	-2.296394131837	-3.5166650484631	0.00043700486981208	0.0096402717586444	0.0096402717586444	1
786	Il1rap	24.8365	6.09039	2.0278553613255	2.045309495907	3.515687247533	0.00043861734091607	0.0096635324333887	0.0096635324333887	1
789	Tnk2	4.90424	22.7963	-2.2166981964364	-2.1992440618549	-3.5050915591019	0.00045645027856735	0.010018186912485	0.010018186912485	1
790	Gm20594	48.5292	20.2893	1.2581339859726	1.2755881205541	3.5022715827454	0.00046130913878837	0.010112013109365	0.010112013109365	1
791	Nudt4	71.9208	121.486	-0.75630909413579	-0.73885495955428	-3.5013922600794	0.00046283406728377	0.01013261383458	0.01013261383458	1
792	Isyna1	18.3912	3.04843	2.5928772932478	2.6103314278293	3.5009299439285	0.00046363770491634	0.010137391585904	0.010137391585904	1
793	Fdx1	34.1049	11.2952	1.5942692162076	1.6117233507891	3.4997515933123	0.00046569190703035	0.01016946627244	0.01016946627244	1
794	Mir350	0	11.9616	-4.5803384741957	-4.5628843396142	-3.4973918265747	0.00046983120956439	0.010240487169322	0.010234046611354	1
795	Mir666	0	11.9616	-4.5803384741957	-4.5628843396142	-3.4973918265747	0.00046983120956439	0.010240487169322	0.010234046611354	1
796	Grem1	12.5091	36.7948	-1.5565238980361	-1.5390697634545	-3.4940644244303	0.00047572620288751	0.010349435496737	0.010349435496737	1
800	C1ra	26.5035	7.10539	1.8991971484537	1.9166512830352	3.4800345096509	0.00050134920009823	0.010852330122626	0.010852330122626	1
801	Sdc1	97.0002	153.263	-0.65994982364837	-0.64249568906686	-3.4774891054349	0.00050613361878753	0.010942217074337	0.010942217074337	1
802	Got1	15.5106	41.6275	-1.4242824223852	-1.4068282878037	-3.4758716214906	0.00050919597241997	0.010994696576554	0.010994696576554	1
803	Snora34	24.3546	55.4418	-1.1867798089162	-1.1693256743347	-3.4742665255711	0.00051225193950331	0.011046907641817	0.011046907641817	1
804	Palm3	11.0917	0	5.5578792043206	5.5753333389021	3.4738624871994	0.00051302388330935	0.011049794262771	0.011049794262771	1
806	Smim15	48.3826	89.6407	-0.88966561541036	-0.87221148082885	-3.469367549673	0.00052168522449427	0.011208465300952	0.011208465300952	1
807	Ppme1	19.7763	48.334	-1.2892658597785	-1.271811725197	-3.4661229690234	0.00052802172270167	0.011330547920725	0.011330547920725	1
808	Sdc4	148.424	95.9583	0.62924488890303	0.64669902348454	3.4629110720082	0.00053436497296052	0.011452473065294	0.011452473065294	1
809	Aldh1l1	16.8062	2.47778	2.7618735553537	2.7793276899352	3.4604993618111	0.0005391745118038	0.011541267022134	0.011541267022134	1
811	Dag1	36.643	13.0576	1.4886478707408	1.5061020053223	3.4525307528462	0.00055535416801507	0.011858283757727	0.011858283757727	1
813	Mmp23	165.703	110.27	0.5875593768961	0.60501351147761	3.4479280396313	0.00056490452053628	0.012032535771374	0.012032535771374	1
814	Mocs1	23.7043	5.77323	2.0376981829737	2.0551523175552	3.4452655153919	0.00057049870238114	0.012136764163556	0.012136764163556	1
815	Ryk	82.775	134.586	-0.70126133397523	-0.68380719939372	-3.443480773058	0.00057427742584221	0.01220216218811	0.012198339397184	1
817	Emc2	150.107	97.6171	0.6207854582777	0.63823959285921	3.4419798160093	0.00057747333607997	0.012240031531086	0.012240031531086	1
818	Ifit1	21.7632	4.82791	2.1724200147226	2.1898741493041	3.4364219149506	0.00058945224000077	0.012478660684711	0.012478660684711	1
820	Mir1927	11.3927	0	4.5100377923281	4.5274919269096	3.4282449713742	0.00060749701128561	0.012813673257531	0.012798084847242	1
821	Mir680-1	11.3927	0	4.5100377923281	4.5274919269096	3.4282449713742	0.00060749701128561	0.012813673257531	0.012798084847242	1
822	Mir697	11.3927	0	4.5100377923281	4.5274919269096	3.4282449713742	0.00060749701128561	0.012813673257531	0.012798084847242	1
823	Snrpd1	51.5247	93.1552	-0.85437210407133	-0.83691796948982	-3.4144380939948	0.00063913716005129	0.01344828456939	0.01344828456939	1
826	Gzmd	0	11.0403	-4.8386066763401	-4.8211525417586	-3.3948046963898	0.00068677572791519	0.014398178305457	0.014398178305457	1
827	Id1	89.8233	50.7211	0.82450369210045	0.84195782668196	3.3905101121409	0.00069762680801765	0.014607984805855	0.014607984805855	1
828	Coch	8.89118	29.5773	-1.7340435549767	-1.7165894203952	-3.3881619297497	0.00070362710270606	0.014715833982561	0.014715833982561	1
829	Gm13889	15.1586	1.98269	2.9346054866722	2.9520596212538	3.3878121822927	0.00070452490257141	0.014716836836947	0.014716836836947	1
832	Hs6st2	13.4927	37.4487	-1.4727365653205	-1.455282430739	-3.3818232373657	0.00072006462288856	0.014987210426155	0.014987210426155	1
833	Npr3	40.804	16.0477	1.3463440447666	1.3637981793481	3.381422483074	0.00072111575799417	0.014991070325552	0.014991070325552	1
835	Cldn10	10.5523	0	6.5890210885538	6.6064752231353	3.3580318936948	0.00078499555114748	0.016279961627809	0.016279961627809	1
836	Chp1	129.577	82.1904	0.65676786241045	0.67422199699195	3.3572125991306	0.00078732548305367	0.016308750466555	0.016308750466555	1
837	Mir219a-1	10.9496	0	4.4528062625625	4.470260397144	3.3515050045063	0.00080373586260493	0.016628786060609	0.016627258397748	1
838	Thra	34.1195	12.0571	1.500713556212	1.5181676907935	3.351199822391	0.00080462219422029	0.016627258397748	0.016627258397748	1
839	Adamts2	52.8927	24.258	1.1246080126968	1.1420621472783	3.3502349733487	0.00080743034774893	0.016665400872429	0.016665400872429	1
840	Pink1	53.8012	24.8916	1.1119793836153	1.1294335181968	3.3488438405423	0.00081149519438729	0.016729359858577	0.016729359858577	1
841	Kng1	13.497	1.43637	3.2321394413129	3.2495935758944	3.3421074699167	0.00083144861952298	0.01712032787667	0.01712032787667	1
842	Tgfbi	1.58825	14.0852	-3.1486701248687	-3.1312159902871	-3.3377134095133	0.00084470826096608	0.017372699471674	0.017367630672404	1
844	Vit	30.4593	9.95523	1.613356234276	1.6308103688575	3.3355295601579	0.00085137101922928	0.017468236895727	0.017468236895727	1
845	Acaa2	52.8653	24.4104	1.1148251333561	1.1322792679376	3.3263108106384	0.00088003738277833	0.018035038292985	0.018035038292985	1
846	Phf10	26.6593	57.2341	-1.1022360592218	-1.0847819246403	-3.3230888231466	0.0008902656199072	0.018223084798975	0.018223084798975	1
847	Dynlt3	85.883	136.537	-0.66884746602656	-0.65139333144506	-3.3225579707856	0.0008919613528203	0.018236239370471	0.018236239370471	1
848	Pik3ip1	32.228	11.0678	1.5419461814764	1.5594003160579	3.3216215832483	0.00089495981094222	0.018275965856234	0.018273251226723	1
849	Arsj	28.3583	8.80633	1.6871582370996	1.7046123716811	3.3213341472595	0.00089588209802434	0.018273251226723	0.018273251226723	1
850	Mir6361	0	10.9171	-4.4485177669638	-4.4310636323823	-3.3196499811607	0.00090130375715566	0.018362208426664	0.01834458026194	1
851	Adam12	34.1076	12.2127	1.4817110539631	1.4991651885446	3.3195898713898	0.00090149782311664	0.01834458026194	0.01834458026194	1
852	Tgif1	9.13106	29.4391	-1.6888793129925	-1.671425178411	-3.3171618190294	0.0009093693078246	0.018483037915022	0.018483037915022	1
853	Ctsh	131.694	84.4347	0.64128168957848	0.65873582415999	3.3156770429438	0.00091421412689205	0.01855972571558	0.01855972571558	1
854	Steap4	10.4227	0	6.8552805972247	6.8727347318062	3.3153019718068	0.00091544176130469	0.018562886394044	0.018562886394044	1
855	Arhgap20	13.3081	1.43235	3.2158486434616	3.2333027780431	3.3113351473453	0.00092851930347306	0.01880604535467	0.018802424631617	1
856	Enpp5	33.5022	11.8883	1.4947134089054	1.5121675434869	3.3110619461962	0.000929426314296	0.018802424631617	0.018802424631617	1
857	Gng10	83.753	133.603	-0.6737396300218	-0.65628549544029	-3.3085387926749	0.00093784191189238	0.018950534875426	0.018950534875426	1
858	Slc1a4	12.2284	34.6249	-1.5015742547973	-1.4841201202158	-3.2997258756059	0.00096779310837353	0.019532952514807	0.019532952514807	1
859	Nudt9	56.0943	26.8509	1.0628837335054	1.080337868087	3.2987738619659	0.00097108105595505	0.019576496677501	0.019576496677501	1
861	Cxcr6	1.16324	12.6994	-3.4485396466905	-3.431085512109	-3.2969321786462	0.00097747101622825	0.019659541914082	0.019659541914082	1
862	Mir16-2	10.6131	0	4.4077742121574	4.4252283467389	3.2919537724638	0.0009949396451337	0.019987668021787	0.019987668021787	1
863	Agt	10.0412	0	5.197883124721	5.2153372593025	3.2908671353772	0.00099879075239581	0.020041783846163	0.020041783846163	1
864	Fzd1	51.2616	23.5644	1.1212695616545	1.138723696236	3.2904333058498	0.0010003321213458	0.020049480723779	0.020049480723779
865	Epas1	13.7155	1.64284	3.0615433319205	3.078997466502	3.2879606454112	0.0010091594525503	0.02020302224256	0.02020302224256
866	Cldn1	9.94862	0	6.0779217572481	6.0953758918296	3.2869072151631	0.0010129420283239	0.020255331529428	0.020255331529428
867	Tm4sf1	38.201	73.2303	-0.93883030143788	-0.92137616685637	-3.2843937577846	0.0010220202306574	0.020413292196419	0.020413292196419
868	Mir1931	0	10.7021	-4.4198220094878	-4.4023678749063	-3.2817920778066	0.0010314963465142	0.020578827456896	0.020578827456896
869	H2-T23	35.2392	13.1344	1.4238308751766	1.4412850097581	3.2766377315865	0.0010505106176999	0.020934053356397	0.020934053356397
871	Gabarapl1	95.9177	56.6916	0.75866207820562	0.77611621278713	3.2667272686577	0.0010879843984224	0.021631028504569	0.021631028504569
872	Sec23a	58.8405	100.787	-0.77642815384984	-0.75897401926833	-3.2645975450197	0.0010961971046833	0.021769317960781	0.021769317960781
873	Adk	99.4898	59.559	0.74022909254197	0.75768322712347	3.2583795889968	0.0011205041649538	0.022226541379731	0.022226541379731
874	Hist1h3b	13.2099	35.8507	-1.4403817431206	-1.4229276085391	-3.2535062489128	0.0011399021817215	0.022585453181775	0.022585453181775
875	Mir27a	48.9761	22.2997	1.1350535941314	1.1525077287129	3.2474079429972	0.0011646133202861	0.02304869584845	0.023033749789583
876	Rgs5	10.5998	0	4.1851374470825	4.2025915816641	3.2472674898476	0.0011651882436724	0.023033749789583	0.023033749789583
877	Dkk2	23.4457	6.38772	1.8759503731243	1.8934045077058	3.2464818969339	0.001168408786715	0.023071077490928	0.023071077490928
878	Nmb	11.9137	1.05248	3.5007568125008	3.5182109470823	3.2449071265316	0.0011748893534469	0.023172618375444	0.023172618375444
879	Mir6398	0	10.4409	-4.3841741716968	-4.3667200371153	-3.2351714907521	0.0012156968996413	0.023950197054709	0.023950197054709
880	Lrrfip1	50.0539	88.6887	-0.82526781717358	-0.80781368259207	-3.2319738723474	0.0012293829637347	0.024192300889765	0.024192300889765
886	Galnt15	15.1486	0	10.636887283025	10.654341417607	3.2175244129583	0.0012930202254709	0.02527227002763	0.02527227002763
887	Higd1a	22.5002	49.9447	-1.1503937658015	-1.13293963122	-3.21512620151	0.0013038718539005	0.025455635731674	0.025455635731674
888	Abcc1	26.2635	55.4776	-1.0788461875045	-1.061392052923	-3.2141548693201	0.0013082908858193	0.025513145574024	0.025485392469127
889	Rrm1	124.723	80.126	0.63838517285938	0.65583930744089	3.2141442158681	0.0013083394297542	0.025485392469127	0.025485392469127
890	Psmb6	96.5754	148.022	-0.61608396158843	-0.59862982700692	-3.208477989039	0.0013343952278677	0.025963732765151	0.025963732765151
892	2010204K13Rik	16.4019	3.0063	2.4478020579371	2.4652561925186	3.201914734987	0.0013651739999824	0.02650304726199	0.02650304726199
894	Mir345	10.1023	0	4.336611884977	4.3540660195585	3.1993189631032	0.0013775267206674	0.026683031568006	0.026667319296831
895	Snora69	24.7217	53.0651	-1.1019853829958	-1.0845312484143	-3.1991664872839	0.0013782555160053	0.026667319296831	0.026667319296831
896	Glrx	37.0991	14.7374	1.3319021645362	1.3493562991177	3.1981043457139	0.0013833421550935	0.026735866182761	0.026735866182761
897	Timp4	10.9547	0	8.3509956935976	8.3684498281791	3.1936314041836	0.0014049537964819	0.027123283047577	0.027123283047577
898	Bcl2l1	30.5652	10.7168	1.5120158209789	1.5294699555604	3.189207147207	0.0014266360750364	0.02751119923319	0.027492207509151
901	Msrb3	73.5475	118.663	-0.69012195426751	-0.672667819686	-3.1868222275931	0.0014384515805253	0.027646688146456	0.02764308738922
902	Cp	14.7817	2.32749	2.6669653247462	2.6844194593278	3.1865390417027	0.001439860531563	0.02764308738922	0.02764308738922
903	Gstm1	31.5994	11.3598	1.4759597301401	1.4934138647216	3.1861149834906	0.0014419727515882	0.027652981328076	0.027652981328076
904	Lpl	10.8114	0	3.7980178391904	3.8154719737719	3.1840144435317	0.0014524776475216	0.02782362325457	0.02782362325457
905	Trnp1	33.3718	12.4652	1.4207234737732	1.4381776083547	3.1834751893377	0.0014551858369189	0.027844699599917	0.027842829077147
906	Fgfr2	41.9513	17.9885	1.2216406278839	1.2390947624654	3.1831749045741	0.0014566959140669	0.027842829077147	0.027842829077147
908	Pdlim1	46.1866	82.8421	-0.84288977858869	-0.82543564400718	-3.1820276926987	0.0014624783408684	0.02789178130927	0.02789178130927
910	Iqgap1	59.5439	100.428	-0.7541359351568	-0.73668180057529	-3.1753058298428	0.0014967865686661	0.028483354955594	0.028483354955594
911	Erh	70.464	114.444	-0.69968354901592	-0.68222941443441	-3.1688818479905	0.0015302658908061	0.029088490045103	0.029088490045103
912	Gltp	34.5399	13.2797	1.3790413506645	1.396495485246	3.1676437802258	0.0015367969673044	0.029180606450449	0.029180606450449
913	Sh3pxd2a	48.5252	22.5765	1.1039123144624	1.1213664490439	3.1621011234562	0.0015663516026662	0.029709212161414	0.029709212161414
914	Ccbe1	14.1713	2.12919	2.7345955088163	2.7520496433979	3.1613895784824	0.0015701833871998	0.029749306035163	0.029749306035163
916	Hist1h2ab	14.4439	37.0269	-1.3581134307628	-1.3406592961813	-3.1600121151761	0.0015776257869159	0.029825049947622	0.029825049947622
917	Mpp1	57.7401	29.0814	0.98947688284722	1.0069310174287	3.1593445322208	0.0015812443931	0.029860860583765	0.029860860583765
918	Rtn2	18.3685	4.08265	2.169656020856	2.1871101554375	3.1545766737861	0.0016073113771157	0.030320055683565	0.030320055683565
919	Tmem2	16.9314	40.8686	-1.2712915533367	-1.2538374187552	-3.1519730677651	0.0016217123053073	0.030558424364535	0.030526079510764
920	Ebf1	43.6497	19.3199	1.1758841116021	1.1933382461836	3.1519647377882	0.0016217585696081	0.030526079510764	0.030526079510764
922	Hax1	33.739	65.3767	-0.95435934265719	-0.93690520807568	-3.147095480855	0.0016490110387628	0.030971718175982	0.030971718175982
923	Timm17a	73.7392	118.149	-0.68010374878913	-0.66264961420762	-3.1379962820384	0.0017010703466076	0.031914881031641	0.031914881031641
925	Gpm6b	18.2961	4.13959	2.1439763659775	2.161430500559	3.125264070783	0.0017764550765636	0.033257159525245	0.033257159525245
926	Dusp14	22.9335	6.61312	1.7940535631672	1.8115076977487	3.1158511172951	0.0018341484953066	0.034300161439767	0.034300161439767
928	Kazald1	31.6552	11.7564	1.4289961594256	1.4464502940071	3.1138833164609	0.0018464249482458	0.034455324168935	0.034455324168935
929	Eef1e1	15.9014	38.8876	-1.2901564100051	-1.2727022754236	-3.1107042492102	0.001866417686598	0.034790909665036	0.034790909665036
930	Mir219a-2	9.62439	0	4.2666951046572	4.2841492392387	3.1100355033065	0.001870648577552	0.034832281094051	0.034832281094051
931	Cfh	13.8033	2.10583	2.7125523381423	2.7300064727238	3.1069262031982	0.0018904358408636	0.035162918857395	0.035162918857395
932	Lrp1	107.883	67.9202	0.66755493335178	0.68500906793329	3.1064820822189	0.0018932778191933	0.035177995702758	0.035177995702758
933	Fam101b	19.5644	44.4601	-1.1842803268686	-1.1668261922871	-3.1058950315304	0.0018970404419799	0.035210127903286	0.035210127903286
934	Ak4	0	10.8765	-3.6027541721237	-3.5853000375422	-3.1042092485978	0.00190788345225	0.035373466533848	0.035373466533848
935	C3	11.2584	0	9.0942888373844	9.111742971966	3.0991379967562	0.0019408459746586	0.035946128067553	0.035946128067553
936	Pmepa1	6.59045	23.1869	-1.8148610682396	-1.7974069336581	-3.0974420614709	0.0019519854906308	0.036113817031254	0.036113817031254
937	Celf2	18.7669	4.46753	2.0706410367844	2.0880951713659	3.09693349999	0.001955337328389	0.03613722146821	0.03613722146821
938	Gns	111.156	70.7024	0.65275473113264	0.67020886571415	3.0930517855752	0.0019810956179106	0.036574235410829	0.036574235410829
939	Uck2	37.7701	70.2551	-0.89535835465333	-0.87790422007182	-3.0883759955255	0.0020125366465243	0.037115119390693	0.037115119390693
941	Gatb	18.9252	4.61141	2.0370287001411	2.0544828347226	3.0777809042761	0.0020854818227424	0.038378627762413	0.038378627762413
942	Nr1h3	12.5286	1.65381	2.9213598073329	2.9388139419144	3.0731562081936	0.0021180758383408	0.038937069312684	0.038915423149396
943	Rabggtb	29.6209	58.7565	-0.98813298410267	-0.97067884952116	-3.0730055335734	0.0021191455812139	0.038915423149396	0.038915423149396
944	Pyhin1	9.58648	0	7.7932651166294	7.8107192512109	3.0713800519723	0.0021307175387686	0.039086478409804	0.039086478409804
945	Ipo5	58.7813	97.9223	-0.73628017865652	-0.71882604407501	-3.0689248645561	0.0021483061408462	0.039367425863528	0.039367425863528
946	Bcat2	31.1149	11.6511	1.4171394409818	1.4345935755633	3.0681855769423	0.0021536283065417	0.03942323613571	0.03942323613571
947	Mirlet7f-1	43.6858	19.8909	1.1350558551762	1.1525099897578	3.0670068022084	0.0021621393688039	0.039537241235034	0.039537241235034
948	Ampd3	26.7112	8.99145	1.5708190956306	1.5882732302121	3.0646019592097	0.0021795986663971	0.039814462137129	0.039814462137129
949	Col14a1	10.5452	0	3.5216750675558	3.5391292021373	3.0598950946234	0.0022141453180574	0.040402902500316	0.040402902500316
950	Sash1	45.8849	21.4603	1.0963492193558	1.1138033539373	3.058135480927	0.0022271885846852	0.040598131285257	0.040598131285257
952	Wipi1	70.7486	39.5784	0.83798830858972	0.85544244317123	3.0500831465402	0.0022877802052957	0.041615010309986	0.041615010309986
954	Mir546	119.683	78.1959	0.61405337305681	0.63150750763832	3.0445266955335	0.0023304674664076	0.042302625907526	0.042302625907526
955	Unc5b	18.3579	42.0423	-1.1954405615232	-1.1779864269417	-3.0432568875948	0.0023403245616195	0.042437068516821	0.042437068516821
956	Hist1h1d	35.9144	67.1517	-0.9028615096196	-0.88540737503809	-3.0412387208535	0.0023560695012714	0.042677882378155	0.042677882378155
957	Gas5	54.1964	91.5228	-0.75593416620458	-0.73848003162307	-3.0376985047817	0.0023839233532068	0.043137304814505	0.043137304814505
958	Filip1l	8.65002	26.425	-1.6111280980387	-1.5936739634572	-3.0372146849456	0.0023877532966743	0.043161507138318	0.043161507138318
959	Mir669g	0	9.32781	-4.2215384022981	-4.2040842677166	-3.0281248676579	0.0024607638478778	0.044434877532534	0.044434877532534
961	Snord67	9.17675	0	4.1979833051575	4.215437439739	3.0239340399045	0.0024951083185959	0.044961280700442	0.044936236910825
962	Lcn2	9.17466	0	4.1976546946967	4.2151088292782	3.0235261354399	0.0024984744693221	0.044975137614606	0.044936236910825
963	Adgrl2	23.0098	7.01889	1.7129336446264	1.7303877792079	3.0234735933596	0.0024989083643313	0.044936236910825	0.044936236910825
964	Vcam1	49.5579	24.2832	1.0291565049459	1.0466106395274	3.0214292647581	0.0025158441426747	0.045193851679148	0.045193851679148
966	Tmem70	27.4134	55.0163	-1.0049778453353	-0.98752371075384	-3.0163703221483	0.00255820615768	0.045859685333896	0.045859685333896
967	Pycard	9.14934	0	4.1484847496861	4.1659388842676	3.0096648599643	0.002615360993574	0.046835787306847	0.046807310100052
969	U2af2	43.3312	76.8009	-0.82571702674494	-0.80826289216343	-3.0090013396051	0.0026210796019238	0.046841316270913	0.046841316270913
970	Kdelr3	74.952	117.655	-0.65052375196087	-0.63306961737936	-3.0070203363807	0.0026382211295741	0.047099046701892	0.047099046701892
972	Top2a	17.5585	40.4535	-1.2040949261556	-1.1866407915741	-3.0026232777026	0.0026766354064236	0.047686517832344	0.047686517832344
973	Mrgpra6	114.603	74.599	0.61941661409847	0.63687074867998	3.0017167017647	0.002684618862383	0.047779593874497	0.047779593874497
974	Rars	47.6645	82.421	-0.79009680506647	-0.77264267048496	-2.998237802383	0.0027154570006112	0.048278818151524	0.048278818151524
975	Zcchc24	55.8303	28.9722	0.94637906873818	0.96383320331968	2.9959780260061	0.0027356614644136	0.048588153414617	0.048588153414617
976	Klf13	21.3853	6.22181	1.78121320194	1.7986673365215	2.9941669757087	0.0027519529452757	0.048827427411208	0.048827427411208
977	Ssb	67.5035	108.024	-0.67831766392362	-0.66086352934211	-2.9933528454621	0.0027593053690749	0.048907769781238	0.048907769781238
978	Cdr2	17.3988	40.1181	-1.2052654748537	-1.1878113402722	-2.9924921587797	0.0027670977533337	0.048995738031166	0.048995738031166
980	Entpd2	8.58008	0	4.6075405099456	4.6249946445271	2.9882695681075	0.0028056197652409	0.049576446402732	0.049576446402732
981	Hist1h4b	25.1805	51.5104	-1.0325568128304	-1.0151026782489	-2.9858823091064	0.0028276144390064	0.049914168440647	0.049914168440647
983	Psmc6	80.7591	124.575	-0.62531783591119	-0.60786370132968	-2.984006703692	0.0028450053850351	0.050118980928436	0.050118980928436
984	Ptgs2os2	1.06247	10.7	-3.3321167857573	-3.3146626511758	-2.9831814937079	0.0028526877687514	0.050203246027914	0.050203246027914
985	Slc7a2	21.2474	6.1892	1.7794614648995	1.796915599481	2.9824961095341	0.0028590828213659	0.05026470783512	0.05026470783512
987	Pdzrn3	8.83022	26.2543	-1.5720324432368	-1.5545783086553	-2.9731964620292	0.0029471574513015	0.051708131290971	0.051708131290971
988	Hist1h2bg	23.0222	48.2661	-1.0679845548638	-1.0505304202823	-2.9728853109843	0.0029501466372483	0.051708187568045	0.051708187568045
990	Flrt2	45.3433	21.6779	1.0646643860509	1.0821185206324	2.969813740823	0.0029798035986982	0.05212248375622	0.052101801290512
992	Tmem47	8.66227	25.9188	-1.5811818787082	-1.5637277441267	-2.9668169281202	0.00300900066334	0.052527081136149	0.052527081136149
993	Lum	10.3576	1.0323	3.3267555462176	3.3442096807991	2.9639779561202	0.0030369004087462	0.05296072948465	0.05296072948465
994	3110062M04Rik	21.3886	6.36688	1.7481835750259	1.7656377096074	2.9562831507386	0.0031137109668024	0.054245606450822	0.054245606450822
995	Tceal8	48.0122	82.3263	-0.77795234411028	-0.76049820952877	-2.9556291974669	0.0031203197941513	0.054306108417404	0.054306108417404
997	Chrdl1	8.82354	0	4.1238489480266	4.1413030826082	2.9506848016385	0.0031707030270229	0.055072281162442	0.055018785752714
1000	Gsta4	51.1319	86.3205	-0.75547958563292	-0.73802545105141	-2.9485116433517	0.0031930811123321	0.055294585622256	0.055294585622256
1001	Cilp	7.99771	0	5.4720201359156	5.4894742704971	2.9479339496912	0.003199054078529	0.055342676801086	0.05532493283755
1002	Cltb	100.6	63.9285	0.65409915677482	0.67155329135633	2.9477243967102	0.0032012232316928	0.05532493283755	0.05532493283755
1003	Oplah	10.9276	1.29561	3.0762731668302	3.0937273014117	2.94135280591	0.0032678210810602	0.056419598864126	0.056419598864126
1004	Mir297a-3	8.75694	0	4.1304268266694	4.1478809612509	2.9408427730612	0.003273206288112	0.056456288138681	0.056456288138681
1005	Cct7	83.4705	127.112	-0.60676191631552	-0.58930778173401	-2.9316403817834	0.0033717693819681	0.058098438196558	0.058098438196558
1007	Scrn1	38.4455	17.1904	1.1612116273417	1.1786657619232	2.9291662107916	0.0033987262877627	0.058446616807535	0.058446616807535
1008	Fgfrl1	29.3147	11.2281	1.3845104746068	1.4019646091883	2.9268716553781	0.0034239014342312	0.058821132079942	0.058821132079942
1009	Phyhd1	15.8335	37.1186	-1.2291620985436	-1.2117079639621	-2.9242211928743	0.0034531926993716	0.059265548042634	0.059265548042634
1010	Camk2d	50.8988	25.954	0.97167474125904	0.98912887584055	2.9228317296652	0.0034686391391328	0.05947170690333	0.05947170690333
1011	Vegfc	12.044	1.79428	2.7468376655808	2.7642918001623	2.9212226148842	0.0034866059738772	0.059720628733563	0.059720628733563
1012	Irak3	15.9334	3.59553	2.147777801577	2.1652319361585	2.9197016930311	0.0035036658910832	0.059953539758782	0.059953539758782
1013	Cfl2	33.6655	62.6128	-0.89518672706591	-0.8777325924844	-2.9150733844544	0.0035560491517808	0.060789835302457	0.060789835302457
1014	Carhsp1	84.0921	51.1762	0.71649724687998	0.73395138146149	2.9137544054446	0.0035711072849311	0.060987046206264	0.060886827897944
1015	Mak16	30.1106	57.6968	-0.93821984956933	-0.92076571498782	-2.9136752755491	0.0035720125136066	0.060942404628695	0.060886827897944
1017	Acadsb	70.7449	40.8355	0.79280225527581	0.81025638985732	2.9116071503827	0.0035957455572213	0.061226672383874	0.061226672383874
1018	Gria3	34.7622	14.8327	1.228738153248	1.2461922878295	2.9106279455997	0.0036070325056644	0.061358528389578	0.061358528389578
1019	Apoe	10.6548	1.25288	3.0881833666825	3.105637501264	2.9095763038959	0.0036191902888108	0.061504924662745	0.061504924662745
1021	Steap3	12.5028	2.03227	2.6210872312159	2.6385413657974	2.9035325544913	0.0036897860793521	0.062581807577023	0.062537281631701
1022	Mir7063	39.1506	17.8259	1.1350594998381	1.1525136344196	2.9034488809442	0.0036907721792226	0.062537281631701	0.062537281631701
1023	Sdc3	21.008	44.6471	-1.0876276484825	-1.070173513901	-2.9028214109397	0.0036981746053369	0.062601456149188	0.062601456149188
1024	Acot2	4.14275	17.1599	-2.0503804788777	-2.0329263442962	-2.8932697721087	0.0038125368129382	0.064474316396143	0.064474316396143
1025	Fbxl5	50.8685	26.1627	0.95926111776585	0.97671525234736	2.8915043264753	0.00383402313616	0.064774418194032	0.064774418194032
1026	Ncam1	11.1354	29.4496	-1.4030946559525	-1.385640521371	-2.890117966615	0.0038509728589566	0.064997365495665	0.064965327147015
1028	Selt	50.7932	85.0788	-0.74416431743489	-0.72671018285338	-2.8880044155802	0.0038769442996287	0.065308408985089	0.065281521926515
1029	Thsd7a	16.3805	3.91684	2.0642172930311	2.0816714276126	2.8876479504809	0.0038813402115116	0.065318919769432	0.065281521926515
1030	Serpina3g	7.88465	0	4.8161303308667	4.8335844654482	2.887522545693	0.0038828877741127	0.065281521926515	0.065281521926515
1031	Manf	43.9458	76.0834	-0.79185642819838	-0.77440229361687	-2.8863332227446	0.0038975925487834	0.065465189299013	0.06542830829028
1032	Tcp11l2	18.4219	4.99011	1.8842783427256	1.9017324773071	2.8862054738462	0.0038991750393006	0.06542830829028	0.06542830829028
1033	Ech1	82.6487	50.33	0.71557352938631	0.73302766396781	2.8854641793769	0.0039083693549855	0.065519101762133	0.065519101762133
1034	Abce1	61.6749	99.0323	-0.68321567456225	-0.66576153998074	-2.8848472549703	0.0039160361104231	0.065584136677173	0.065584136677173
1035	Lonp1	22.4496	46.535	-1.0516264675436	-1.0341723329621	-2.881787963895	0.0039542572889747	0.066160264225289	0.066160264225289
1037	Hist1h4k	18.7384	41.0722	-1.1321644541407	-1.1147103195592	-2.8777501871239	0.0040052217299025	0.066883726804939	0.066883726804939
1038	C2	26.425	9.69873	1.4460357205004	1.4634898550819	2.8700560505321	0.0041039904366693	0.068467054327363	0.068467054327363
1039	Plin3	74.7172	44.2912	0.75442030629391	0.77187444087543	2.8695190712832	0.0041109654055281	0.068517408977411	0.068517408977411
1041	Trim30d	11.1839	1.55732	2.8442860394191	2.8617401740006	2.8654207439483	0.004164555061761	0.069277233433732	0.069277233433732
1042	Mirlet7e	35.2369	64.1759	-0.86494461587024	-0.84749048128873	-2.8645265283524	0.0041763317125496	0.069406464746853	0.069393048974309
1043	Cycs	24.3458	49.0781	-1.0114064896993	-0.99395235511779	-2.8642839462423	0.004179531678709	0.069393048974309	0.069393048974309
1045	Zhx3	18.1102	4.9114	1.8825962486866	1.9000503832681	2.8599859938614	0.0042365971876245	0.070205888514922	0.070205888514922
1047	Prmt1	32.3118	60.1271	-0.895954256004	-0.87850012142249	-2.8587387329566	0.0042532893234464	0.070347861713583	0.070299992393906
1049	Arrdc4	31.6892	13.099	1.2745345608971	1.2919886954786	2.858349227753	0.0042585142935385	0.070299992393906	0.070299992393906
1050	Gprc5b	13.755	2.71478	2.3410489447141	2.3585030792956	2.8575979638429	0.0042686084761659	0.07039951712549	0.07039951712549
1051	3300005D01Rik	13.9031	33.5613	-1.2713920005767	-1.2539378659951	-2.8564927863691	0.004283497377895	0.070577853561377	0.070577853561377
1054	Fhl3	6.63313	21.4982	-1.6964541649329	-1.6790000303514	-2.8437937569782	0.0044579893996335	0.073243835325856	0.073243835325856
1055	Prps2	32.1858	13.5161	1.2517453989078	1.2691995334894	2.841045337776	0.0044965919221175	0.073808040109298	0.073808040109298
1056	A4galt	29.1269	11.5419	1.3354714258814	1.3529255604629	2.8394585737305	0.0045190162364758	0.074105875158192	0.074037805342726
1057	Pcolce2	28.8102	11.3399	1.3451717576555	1.362625892237	2.8394497834682	0.0045191407430422	0.074037805342726	0.074037805342726
1060	Oxct1	92.7301	58.9073	0.65459128173538	0.67204541631689	2.8318997715034	0.00462723505184	0.075594178672371	0.075594178672371
1063	Lmod1	11.6067	29.7069	-1.355840218117	-1.3383860835355	-2.8267781943397	0.0047018883327647	0.076596989895096	0.07657907170592
1064	Adipoq	7.64515	0	7.0095225006805	7.026976635262	2.8265519846556	0.0047052106193393	0.07657907170592	0.07657907170592
1066	D15Ertd621e	30.1378	56.7082	-0.91198325692421	-0.8945291223427	-2.8190837695614	0.0048160947472932	0.078236691124649	0.078236691124649
1067	Hist1h4a	10.3223	27.5514	-1.4163611641219	-1.3989070295404	-2.8157058705618	0.0048670202766616	0.07898986891373	0.07898986891373
1068	Skil	4.5967	17.5421	-1.9321510480543	-1.9146969134728	-2.8122149843203	0.0049201606218943	0.079777548210995	0.079777548210995
1069	Ctsf	40.5427	19.3667	1.0658640243456	1.0833181589272	2.810729895874	0.004942926213374	0.080071705553786	0.080071705553786
1070	Id2	33.0448	14.259	1.21255045656	1.2300045911416	2.8088226305058	0.0049723032739869	0.080472313827692	0.080459469128617
1071	Slc31a2	27.8536	10.8826	1.3558405268372	1.3732946614188	2.8085732613984	0.0049761558836258	0.080459469128617	0.080459469128617
1072	Prelid2	2.71966	13.7257	-2.335381518993	-2.3179273844115	-2.8081996207677	0.0049819334695854	0.080477744302994	0.080477744302994
1075	Ddx39	26.5156	51.5482	-0.95908065690569	-0.94162652232418	-2.8062770339536	0.0050117583527608	0.080733599436985	0.080733599436985
1076	Glce	24.5388	48.7585	-0.99058904392159	-0.97313490934008	-2.805249710487	0.0050277612058126	0.080916115986113	0.080916115986113
1077	Limk1	21.1582	6.82115	1.6331300041551	1.6505841387366	2.8040709900037	0.0050461793080403	0.08113712820551	0.08113712820551
1078	Nutf2-ps1	61.9924	98.2785	-0.6647844802062	-0.64733034562469	-2.8032251197946	0.0050594340261744	0.081274785743285	0.081196579516852
1079	Pi16	7.21958	0	5.5944890491339	5.6119431837154	2.803216614798	0.0050595674584624	0.081201603038177	0.081196579516852
1080	H2-K1	65.2662	37.6172	0.79494357633675	0.81239771091826	2.8029378111279	0.0050639432856846	0.081196579516852	0.081196579516852
1081	2410002F23Rik	13.6536	32.7149	-1.2606664688254	-1.2432123342439	-2.8013211673564	0.0050893840323844	0.081529013218131	0.081529013218131
1082	Hist1h3c	9.9264	26.7496	-1.4301748217432	-1.4127206871617	-2.7951288558226	0.0051879032545717	0.083030425748077	0.083030425748077
1083	Sqrdl	48.5333	25.2017	0.94545390373248	0.96290803831398	2.7910966566905	0.005252978291402	0.083994298312288	0.083994298312288
1085	Ifrd1	25.6042	50.109	-0.96868926395224	-0.95123512937073	-2.7904064384978	0.0052641912424162	0.084018432944628	0.084018432944628
1086	Sult5a1	7.22452	0	6.4080735558029	6.4255276903844	2.7885107937361	0.0052950982914022	0.084433901576622	0.084433901576622
1087	Rpl39l	20.7068	43.1034	-1.0576970550112	-1.0402429204297	-2.7868420213993	0.0053224419068772	0.084791836707812	0.084791836707812
1088	Mir6365	7.99229	0	3.9986089322258	4.0160630668073	2.7830803137965	0.0053845475316675	0.085702398534823	0.085702398534823
1089	Hist1h2bj	19.325	41.042	-1.0866326218576	-1.0691784872761	-2.7810466027209	0.0054183958319576	0.086161947311304	0.086161947311304
1090	Map2k1	40.3496	70.0169	-0.79514881619878	-0.77769468161727	-2.7790513780682	0.0054517901410756	0.086613440250464	0.086613440250464
1091	Islr2	8.14284	0	8.2024479547692	8.2199020893507	2.7750666911716	0.0055190389067902	0.087601463564516	0.087601463564516
1092	Slc3a2	42.7434	73.075	-0.77367625309386	-0.75622211851235	-2.7709992576149	0.0055884554229401	0.088622053625507	0.088584915843438
1093	Rtp4	15.4063	3.77223	2.0300308760039	2.0474850105855	2.7708376885645	0.0055912290244776	0.088584915843438	0.088584915843438
1095	Crebrf	20.1477	6.38871	1.657018595898	1.6744727304795	2.7644251944122	0.0057023180306453	0.090179946426196	0.090179946426196
1096	Bscl2	47.8729	24.9362	0.94096757173081	0.95842170631232	2.761272029108	0.00575766972417	0.090972232311543	0.090972232311543
1098	Mir3473f	47.6962	24.8194	0.94240609071207	0.95986022529358	2.7596199545424	0.0057868637896885	0.091266958329722	0.091266958329722
1100	Wsb2	55.0584	88.7488	-0.68876492676142	-0.67131079217991	-2.7510659457701	0.0059401683713615	0.093514450624424	0.093514450624424
1101	Ids	22.9714	8.12696	1.4990510863432	1.5165052209247	2.7475173989167	0.0060048322787527	0.09444657635891	0.09444657635891
1102	Chd3	38.5912	67.2784	-0.80187149072023	-0.78441735613872	-2.7445085088755	0.0060601583404427	0.09523027403035	0.09523027403035
1104	Cks1b	43.5554	73.7248	-0.75929840826764	-0.74184427368614	-2.7371865381305	0.0061967144267548	0.097199731637783	0.097199731637783
1105	Egfr	47.8815	25.1265	0.9302586240187	0.94771275860021	2.7357363787848	0.0062240866098457	0.097540731061266	0.097540731061266
1106	Gm10052	50.7736	83.0528	-0.70995025221222	-0.69249611763072	-2.7352377942063	0.0062335226569664	0.097600281962647	0.097600281962647
1108	Dhrs9	12.3548	2.38085	2.3755230215623	2.3929771561438	2.7314685288553	0.0063052762635721	0.098545549689783	0.098545549689783
1111	Fam105a	17.8347	5.22367	1.7715512841377	1.7890054187192	2.7241984671205	0.0064457759276584	0.10046939850519	0.10046939850519
1112	Tspan5	21.4766	7.3386	1.549188847204	1.5666429817855	2.7207090935351	0.0065142059819134	0.10144469873093	0.10144469873093
1114	Scn1b	63.9091	37.3287	0.77573610418963	0.79319023877114	2.7170939765212	0.0065857905021507	0.10237534481665	0.10237534481665
1115	Mir423	0	7.78092	-3.9599407465954	-3.9424866120139	-2.7138470350228	0.006650686773391	0.10315265817717	0.10301426015636
1116	Mir6481	0	7.78092	-3.9599407465954	-3.9424866120139	-2.7138470350228	0.006650686773391	0.10315265817717	0.10301426015636
1117	Mir698	0	7.78092	-3.9599407465954	-3.9424866120139	-2.7138470350228	0.006650686773391	0.10315265817717	0.10301426015636
1118	Mir708	0	7.78092	-3.9599407465954	-3.9424866120139	-2.7138470350228	0.006650686773391	0.10315265817717	0.10301426015636
1119	Tasp1	29.9672	12.7342	1.2346759631297	1.2521300977112	2.7125199242488	0.0066773767029718	0.10333523893241	0.10327032946894
1120	Tcea1	40.5484	69.4824	-0.77700259897553	-0.75954846439402	-2.7123424753236	0.0066809527212592	0.10329826631611	0.10327032946894
1121	Fam150a	2.18508	12.0321	-2.4611304569045	-2.443676322323	-2.712136320599	0.0066851093916196	0.10327032946894	0.10327032946894
1122	Samd9l	41.9172	21.0165	0.99601992153221	1.0134740561137	2.7062767500899	0.0068042315228204	0.10501682467084	0.10489882359026
1123	Myof	101.832	67.7267	0.58839438266065	0.60584851724216	2.7061946826429	0.0068059133725324	0.10494924476593	0.10489882359026
1125	Deptor	6.97364	0	4.7148781868821	4.7323323214636	2.7057633658884	0.0068147587075729	0.10489882359026	0.10489882359026
1126	Peak1	33.1963	14.9451	1.1513498999873	1.1688040345688	2.7036999661629	0.0068572174708375	0.10545864559724	0.10545864559724
1131	Hist1h3e	25.1336	48.4768	-0.9476771384717	-0.93022300389019	-2.6937474072743	0.0070653686798682	0.10817947783314	0.10817947783314
1132	Bud31	47.6909	78.497	-0.71892350926403	-0.70146937468252	-2.689426406949	0.007157492696611	0.10949319878729	0.10949319878729
1133	Rab3d	12.4985	2.56419	2.285179890007	2.3026340245885	2.6852993545525	0.0072464869823311	0.11075676528952	0.11075676528952
1134	P3h1	38.1016	65.8957	-0.79033274369824	-0.77287860911673	-2.6815602768316	0.0073279711494527	0.11190341833781	0.11190341833781
1135	Hk2	7.7292	22.257	-1.5258681434185	-1.508414008837	-2.6775547885378	0.0074161722346098	0.11315053267554	0.11307430672588
1136	Eno3	4.83022	17.1512	-1.8281487139636	-1.8106945793821	-2.6774855203826	0.0074177058636369	0.11307430672588	0.11307430672588
1137	Yars	21.6846	43.4253	-1.0018649846031	-0.98441085002154	-2.6728315881008	0.0075213999773905	0.11455416306814	0.11455416306814
1139	Rnf125	15.2535	3.99439	1.9330932099277	1.9505473445092	2.6710238039713	0.0075620283970498	0.11497071619992	0.11497071619992
1140	5430416N02Rik	6.38534	19.9018	-1.6400635736725	-1.622609439091	-2.6702392646476	0.0075797213974793	0.11513862757908	0.11513862757908
1141	Siglecg	4.191	15.8812	-1.9219535015572	-1.9044993669757	-2.6662288823687	0.0076707449288727	0.11641918486704	0.11641918486704
1142	Hdac2	41.4192	70.0291	-0.75765485778297	-0.74020072320146	-2.6625431343895	0.0077552629231893	0.11759885117414	0.11759885117414
1145	Tnfaip2	61.2194	35.7564	0.775787413893	0.79324154847451	2.6594485419181	0.0078268685137706	0.11837369611613	0.11837369611613
1146	Olfml2b	69.9191	42.5316	0.71715148570357	0.73460562028508	2.6589390195223	0.0078387149459398	0.11844941249462	0.11844941249462
1147	Socs2	43.8392	22.728	0.9477507348663	0.96520486944781	2.6579531012591	0.0078616832370834	0.11869291073808	0.1185131749341
1148	Pdk1	4.67929	16.7506	-1.8398512253574	-1.8223970907759	-2.6577376642356	0.0078667101509598	0.11866534815694	0.1185131749341
1149	Ier3ip1	37.124	64.3268	-0.79306775726681	-0.7756136226853	-2.6575596357812	0.007870866362101	0.1186247108725	0.1185131749341
1150	Hnrnpa2b1	61.9045	96.1176	-0.63475633914297	-0.61730220456146	-2.6574289659329	0.0078739182017503	0.11856751434757	0.1185131749341
1152	Gm12238	19.8135	40.5965	-1.0348716009574	-1.0174174663759	-2.6557227486372	0.0079138648923701	0.11896215133782	0.11896215133782
1153	Eno1	26.4907	49.9679	-0.91551562071472	-0.89806148613321	-2.6550651686872	0.0079293088304985	0.11909092889657	0.11902064186643
1155	Ptbp1	41.3875	69.8937	-0.75596731581003	-0.73851318122852	-2.6546796751671	0.0079383750855069	0.11902064186643	0.11902064186643
1156	Mir218-2	0	7.47834	-3.9027180642909	-3.8852639297094	-2.6480685236547	0.008095311457011	0.12126860596977	0.12126860596977
1158	Gstt1	13.8667	3.34402	2.0519691145935	2.069423249175	2.646828825718	0.0081250469035145	0.12150383180325	0.12150383180325
1159	Emilin2	59.8959	34.8567	0.78102125971275	0.79847539429426	2.6454986564459	0.0081570610954648	0.12187733131162	0.12187733131162
1161	Wwp1	20.9703	7.36016	1.5105384667112	1.5279926012927	2.6397425921683	0.0082969018434177	0.12375318623813	0.12372856011317
1162	Ssh2	11.7534	2.32457	2.3380423814579	2.3554965160394	2.6395182322392	0.0083023957297165	0.12372856011317	0.12372856011317
1163	Abhd11os	17.3036	5.2219	1.7284254853792	1.7458796199607	2.6382880985653	0.0083325758121765	0.12407155231252	0.12407155231252
1164	Tnfrsf1a	75.0077	46.7684	0.68150463132886	0.69895876591037	2.6366014835176	0.0083741147276244	0.12458294221501	0.12458294221501
1165	Nudt22	30.164	13.2738	1.1842463127606	1.2017004473421	2.6347317722352	0.008420379440535	0.12516370023326	0.12515877039411
1166	Mir1193	7.30878	0	3.8696306079779	3.8870847425594	2.6341628305483	0.0084345028035992	0.12521241753101	0.12515877039411
1167	Mir466i	7.30878	0	3.8696306079779	3.8870847425594	2.6341628305483	0.0084345028035992	0.12521241753101	0.12515877039411
1168	Arrb1	15.7678	4.39736	1.8422718303051	1.8597259648866	2.6303051016422	0.0085308268914045	0.12647973397128	0.12647973397128
1169	Ifi27l2a	7.84611	0	3.4777012350511	3.4951553696326	2.6265494015229	0.0086255470843588	0.12777467823767	0.12777467823767
1170	Gm14005	12.6184	29.6623	-1.2331014783001	-1.2156473437186	-2.6207697262073	0.0087731498824504	0.12985011667897	0.12985011667897
1171	Rsl1d1	53.7471	85.3411	-0.66705379203506	-0.64959965745355	-2.6203206963786	0.0087847112529741	0.12991020048485	0.12991020048485
1172	Mcam	1.55593	10.1123	-2.7002621082239	-2.6828079736423	-2.6188761228299	0.0088219977286424	0.13035028555196	0.13032260117179
1174	Chrd	10.7923	1.94236	2.4741198354332	2.4915739700147	2.6130651036876	0.0089734206900921	0.13236177690828	0.13236177690828
1176	Map3k6	13.1065	3.05766	2.099782576673	2.1172367112545	2.6109846550788	0.0090281944660751	0.1329432343274	0.1329432343274
1177	Nucb2	83.1618	53.5733	0.63440681931895	0.65186095390046	2.6103764916212	0.0090442624047418	0.13306668824377	0.13306668824377
1178	Wsb1	34.3097	60.0149	-0.80670421431772	-0.78925007973621	-2.6059059002737	0.0091631631654688	0.13470160996301	0.13468029702644
1181	Snx21	24.6341	9.79497	1.3305437852195	1.347997919801	2.6040076674147	0.0092140695450511	0.13510587833332	0.13510587833332
1183	Kansl2	13.1992	30.4094	-1.2040668603362	-1.1866127257546	-2.6032567786074	0.0092342762805244	0.13517325642421	0.13515444722477
1186	P3h4	65.5156	99.8218	-0.60751644949991	-0.5900623149184	-2.6009010934033	0.0092979256556981	0.13576069020213	0.13576069020213
1187	Stat2	17.0184	5.19173	1.7128081452322	1.7302622798138	2.600077482409	0.0093202713770885	0.13597231629068	0.13586682844483
1188	Maoa	50.1837	27.8366	0.85023583408092	0.86768996866243	2.600054833917	0.0093208865388034	0.13586682844483	0.13586682844483
1189	Fap	15.3065	4.25317	1.8475340064002	1.8649881409817	2.5965074018873	0.0094176876552596	0.13716240296563	0.13716240296563
1190	Cdc42ep2	33.7706	15.9556	1.0817049505902	1.0991590851717	2.5956337992757	0.0094416634110128	0.13739603805757	0.13739603805757
1191	Rab3il1	12.9778	3.03617	2.0957213611056	2.1131754956871	2.5949755287067	0.009459765396854	0.13754387689112	0.13754387689112
1192	Golt1b	39.65	66.9137	-0.75498075448268	-0.73752661990117	-2.5944409597411	0.0094744884429788	0.13764237950257	0.13764237950257
1193	Adcy5	8.33979	0	3.1398336337982	3.1572877683797	2.5936465618576	0.0094964054240978	0.13784514059438	0.13784514059438
1194	Meox2	13.315	3.21462	2.0503323166811	2.0677864512626	2.592324481167	0.0095329811269018	0.13826016262526	0.13826016262526
1195	Lpar1	55.4475	31.8913	0.79795950601601	0.81541364059752	2.5917364229849	0.0095492902343311	0.13838080250035	0.13836470299228
1196	Atp6v1b2	49.0222	27.03	0.85887371851472	0.87632785309623	2.5914886506224	0.0095561693583625	0.13836470299228	0.13836470299228
1197	Glmp	60.4982	35.828	0.75580470729452	0.77325884187603	2.5860774020594	0.009707512838785	0.14043859634857	0.14043859634857
1198	Net1	38.79	19.5668	0.98727694231733	1.0047310768988	2.5848219794	0.0097429287625996	0.14083330332382	0.14083330332382
1199	Nrp2	20.2931	40.6231	-1.0013110678376	-0.9838569332561	-2.5839463592252	0.0097676984461536	0.14107358965141	0.14107358965141
1201	Vimp	55.5885	87.1377	-0.6485105808825	-0.63105644630099	-2.580457737793	0.0098669432678516	0.14226965576135	0.14226965576135
1202	Zbtb38	20.5713	40.9706	-0.99395605310826	-0.97650191852675	-2.5788606198075	0.0099126773835661	0.1428101782456	0.1427766223984
1203	Mir1b	7.06335	0	3.8203525860607	3.8378067206422	2.5786545119598	0.0099185931018814	0.1427766223984	0.1427766223984
1204	Alyref	58.9468	91.3201	-0.63151894254073	-0.61406480795922	-2.5781164430271	0.0099340516103223	0.14288037519597	0.14288037519597
1205	Kctd5	20.9155	41.4466	-0.98668127053578	-0.96922713595427	-2.5777227572193	0.0099453756412741	0.14292453940244	0.14292453940244
1206	Ccnd3	44.2959	23.6257	0.90681609481507	0.92427022939658	2.5766655553454	0.0099758420586009	0.14324349662421	0.14324349662421
1209	Pvr	6.20528	18.9293	-1.6090528461178	-1.5915987115363	-2.5681745891505	0.010223565033348	0.14643629088709	0.14643629088709
1210	Mir3471-1	7.00775	0	3.8089513080165	3.826405442598	2.5659194124859	0.010290273259241	0.14726996862007	0.14726996862007
1211	Nes	0	7.88555	-3.3439807750201	-3.3265266404386	-2.5648524633582	0.010321968450659	0.14760159179196	0.14759030632823
1212	Col28a1	8.17747	0	3.1298465784478	3.1473007130293	2.5645925695772	0.010329702100238	0.14759030632823	0.14759030632823
1213	Hbp1	64.8612	39.4359	0.71784614739142	0.73530028197293	2.5630686004016	0.010375154656501	0.14811752117611	0.14811752117611
1214	Pkp2	1.60083	9.94208	-2.6347276030093	-2.6172734684277	-2.5622416865975	0.010399891866213	0.14834837516245	0.14834837516245
1215	Arl4a	11.9556	2.61786	2.1912266836427	2.2086808182242	2.5605199139954	0.010451567333787	0.14896279137382	0.14896279137382
1216	Ablim3	7.50515	0	3.4437438160494	3.4611979506309	2.558901389609	0.010500352196938	0.14953503206774	0.14953503206774
1218	Ywhag	60.6944	93.215	-0.61899871798216	-0.60154458340065	-2.5571636847575	0.010552954746263	0.15003737055915	0.15003737055915
1219	Atp1b1	14.547	3.97923	1.8701604650569	1.8876145996384	2.5519529954905	0.010712096949905	0.15217504748278	0.1521368835803
1221	Rcc2	22.2607	43.0857	-0.95271016335395	-0.93525602877245	-2.5510573271314	0.010739665889083	0.15231678476761	0.15231678476761
1223	Foxred2	9.66988	1.58158	2.6121314538705	2.629585588452	2.5487704756366	0.010810342214103	0.15306843509535	0.15304362647467
1224	Nfe2l2	41.2413	68.4424	-0.73080054046641	-0.7133464058849	-2.5485419402377	0.010817427891956	0.15304362647467	0.15304362647467
1225	Atp2a2	52.1392	82.3456	-0.65932311701273	-0.64186898243122	-2.5466977488126	0.010874757785944	0.15372912700342	0.15372912700342
1226	Dok1	45.0149	73.2676	-0.70277274388394	-0.68531860930243	-2.5455844665736	0.010909496667425	0.1540944158155	0.1540944158155
1227	Srsf2	37.8631	63.9849	-0.75693894413055	-0.73948480954904	-2.5428964102303	0.010993781696097	0.15515836807768	0.15515836807768
1228	Klhdc8a	32.9269	15.6941	1.0690443936143	1.0864985281958	2.5390469532217	0.011115490440963	0.15674832896266	0.15674832896266
1229	Il1r2	5.91471	0	5.7884899077787	5.8059440423602	2.5382063351651	0.011142227045722	0.1569975148501	0.1569975148501
1231	Gjb5	21.4632	8.09186	1.4073219223256	1.4247760569071	2.5351277404937	0.011240632817583	0.15812675751591	0.15812675751591
1232	Fam107a	5.97375	0	6.43273459259	6.4501887271715	2.534539209164	0.011259532564191	0.15826406283611	0.15826406283611
1233	Smarcd2	37.4839	18.9526	0.98387528838969	1.0013294229712	2.5338217812397	0.011282609781359	0.15845981636966	0.15845981636966
1235	Plin2	60.6069	92.7524	-0.61390256083867	-0.59644842625716	-2.5314348119572	0.011359693080638	0.15928405269426	0.15928405269426
1236	Nedd9	22.7931	43.6288	-0.93668364003517	-0.91922950545366	-2.5301132664019	0.01140257102721	0.1597559243351	0.15966308658774
1237	Mme	11.032	2.24622	2.2961232212926	2.3135773558742	2.5300334663502	0.011405164757697	0.15966308658774	0.15966308658774
1238	Lrrc17	27.3149	49.823	-0.86712375208263	-0.84966961750112	-2.5294759881041	0.011423299013027	0.15978777787447	0.15973587656672
1240	Tmod3	64.383	39.3879	0.70892730195119	0.7263814365327	2.5265302849257	0.011519545599289	0.16087417027652	0.16075054615868
1241	Dhrs1	59.127	35.2714	0.74531823848752	0.76277237306903	2.5265171553333	0.011519976195815	0.16075054615868	0.16075054615868
1242	Sparcl1	5.85741	0	5.905128638303	5.9225827728845	2.5250695976848	0.011567537812394	0.16128426110888	0.16128426110888
1243	Rnasel	10.3407	1.95088	2.4061369056871	2.4235910402686	2.5175027464502	0.011819004808648	0.16465784897132	0.16465784897132
1245	Pnp	56.4681	33.3074	0.76159334874235	0.77904748332386	2.5146325159443	0.01191565130324	0.16573761736403	0.16573761736403
1246	Spry1	11.2761	26.7716	-1.2474351866217	-1.2299810520401	-2.5129002478797	0.011974318776197	0.16641996649069	0.16641996649069
1247	Cdh2	51.9885	29.882	0.79891581958238	0.81636995416389	2.5121174611425	0.012000913655865	0.1666558314183	0.1666558314183
1248	Acadm	51.8861	29.8071	0.79969208119756	0.81714621577907	2.5116905634587	0.012015439394765	0.1667238493583	0.1667238493583
1250	Has2os	6.7824	19.5422	-1.5267251139443	-1.5092709793628	-2.5099991502412	0.012073145213549	0.16725652453042	0.16725652453042
1251	Pafah1b3	10.7062	25.8594	-1.2722422928936	-1.2547881583121	-2.5087200701265	0.012116946475123	0.16772914637067	0.16772914637067
1252	Aldh1a7	7.49016	0	3.2880855835596	3.3055397181411	2.5081287650121	0.012137242891701	0.16787590667379	0.16787590667379
1254	Pde4b	1.94535	10.4305	-2.4227066691347	-2.4052525345532	-2.5020840483443	0.012346461047685	0.17049734127812	0.17029787479249
1255	Fyn	17.4674	35.8626	-1.0378152049037	-1.0203610703222	-2.5020253417303	0.01234850855313	0.1703897391351	0.17029787479249
1256	Mical2	23.7764	44.7192	-0.91136408721633	-0.89390995263483	-2.5019342802343	0.012351685092069	0.17029787479249	0.17029787479249
1257	Mir6385	6.71367	0	3.7471016253488	3.7645557599303	2.4975322179318	0.01250611003039	0.17228982290872	0.17228982290872
1258	Khdrbs3	10.6454	25.6757	-1.2701734495129	-1.2527193149314	-2.4965666322158	0.012540210658775	0.17262227979174	0.17262227979174
1259	Lamb2	75.2356	48.3347	0.63835619098739	0.65581032556889	2.4961889289583	0.012553572012921	0.17266894880679	0.17266894880679
1260	Gng12	55.8052	32.9506	0.76009482487251	0.77754895945402	2.4956676543256	0.012572032944952	0.1727856305617	0.1727856305617
1261	Ncs1	22.2924	42.6029	-0.93439969322137	-0.91694555863986	-2.4949636480739	0.012597003464029	0.17299152179745	0.17299152179745
1262	Eva1c	11.9565	2.80127	2.0936421852056	2.1110963197871	2.4892218443539	0.012802305317877	0.17567156988089	0.17567156988089
1263	Lif	1.28565	8.84248	-2.7819531080002	-2.7644989734186	-2.4880314802433	0.012845236230331	0.17612110514699	0.17612110514699
1264	Zfp521	17.5413	5.89357	1.5735419619192	1.5909960965007	2.4865431127863	0.012899093921014	0.17671962771377	0.17671962771377
1266	Peli2	13.5283	3.63385	1.8964097844609	1.9138639190424	2.483874753008	0.012996150850701	0.17776804445623	0.17776804445623
1268	Lims2	32.3062	15.6047	1.049830442583	1.0672845771645	2.4787645018985	0.013183832004892	0.18005080349268	0.17996976108347
1270	Msn	50.8892	79.89	-0.65065541755969	-0.63320128297818	-2.4782819165077	0.013201678871077	0.18001060866963	0.18001060866963
1271	Taf9	57.2327	87.8224	-0.61774929197483	-0.60029515739332	-2.4774694632247	0.013231773094371	0.18027900446517	0.18027900446517
1273	Ephx2	19.6809	7.23585	1.4435617899277	1.4610159245092	2.4737500485359	0.013370320336387	0.18188046917927	0.18188046917927
1274	Crispld1	5.62148	0	5.9504703543477	5.9679244889292	2.4731231466545	0.01339379811703	0.18205683044946	0.18205683044946
1276	Rab29	36.4357	18.6017	0.96991823338064	0.98737236796215	2.4692863611007	0.013538283090399	0.18373232623545	0.18362266789302
1277	Srsf7	15.8816	33.2963	-1.0680056040811	-1.0505514694995	-2.4692196731362	0.013540806542669	0.18362266789302	0.18362266789302
1278	Ivns1abp	17.7784	36.0204	-1.0186887101991	-1.0012345756176	-2.4686897787482	0.013560872359383	0.18375088157076	0.18365873577416
1281	Dpp7	25.686	11.1255	1.2071120665201	1.2245662011016	2.4677699902843	0.013595764903072	0.18379224108236	0.18379224108236
1282	Adgrd1	17.6597	6.03468	1.5491116583703	1.5665657929518	2.4670326177248	0.013623794680867	0.18402749804102	0.18402749804102
1284	Tmed7	52.7253	81.9977	-0.63708804453995	-0.61963390995844	-2.4627494884436	0.013787621147484	0.18595033910512	0.18595033910512
1287	Prc1	13.1241	29.1625	-1.1518959104826	-1.1344417759011	-2.4593753296801	0.013917902748904	0.18726986938832	0.18726986938832
1288	Mir22	0	6.64285	-3.7318023377646	-3.7143482031831	-2.4576984247341	0.013983054066626	0.18800042490044	0.18800042490044
1290	Nrp1	59.7004	36.3175	0.71707570299455	0.73452983757606	2.4567338522334	0.014020651593209	0.18821366173613	0.18821366173613
1291	Hmgcr	13.422	29.5765	-1.1398516758248	-1.1223975412433	-2.4555954804608	0.014065138314013	0.18866460122677	0.18866460122677
1292	Pdgfrb	54.7755	84.4613	-0.62475970434908	-0.60730556976757	-2.4549842057794	0.014089077843292	0.18883944350797	0.18883944350797
1293	Gbp3	12.5125	3.18827	1.972524354204	1.9899784887855	2.4512584118992	0.01423577124441	0.19065804380468	0.19065804380468
1294	Igf2	6.71377	0	3.5546688452011	3.5721229797826	2.4502423452012	0.014276009349213	0.19104919157676	0.19104919157676
1296	Sox4	9.19882	23.0595	-1.3258405182243	-1.3083863836428	-2.4473685455146	0.014390360808038	0.19228231335863	0.19228231335863
1298	Foxo3	22.0624	8.85913	1.3163528064899	1.3338069410714	2.4443964804059	0.014509471370781	0.19357512767936	0.19357512767936
1299	Srpx	34.9032	17.6585	0.98299651329894	1.0004506478805	2.4432657111581	0.0145550166569	0.19403327440149	0.19403327440149
1300	Clmp	37.5945	19.6143	0.93861576487204	0.95606989945355	2.4419386023292	0.014608630880896	0.1945982007419	0.1945982007419
1303	Dhrs3	56.1281	85.9372	-0.61455954882698	-0.59710541424547	-2.4390580750931	0.014725601515224	0.19570471330708	0.19570471330708
1306	Epha2	6.24409	18.1435	-1.538889550987	-1.5214354164055	-2.4328650150792	0.014979884255604	0.19862684200176	0.19862684200176
1307	Mir31	6.43774	0	3.6865543120928	3.7040084466743	2.431715063985	0.015027523943526	0.19910606895948	0.19910606895948
1309	Appl2	20.4496	7.94383	1.3641659696519	1.3816201042334	2.4176017603546	0.015623164911375	0.20668170112321	0.20668170112321
1310	Edem2	27.2541	12.4417	1.1312896547463	1.1487437893279	2.4161273952313	0.015686571935337	0.20736211160629	0.20736211160629
1311	Sema3e	8.32818	1.27349	2.7092136194852	2.7266677540667	2.4117585877931	0.015875789493885	0.20970331553441	0.20970331553441
1312	Lhfpl2	10.9651	25.5306	-1.219308473998	-1.2018543394165	-2.4095647758586	0.015971560564179	0.21080755662339	0.21072053309777
1313	Thyn1	23.1617	42.9964	-0.89247472424236	-0.87502058966085	-2.4092992823008	0.01598318509843	0.21080031709788	0.21072053309777
1314	Idh2	75.912	49.756	0.60945745315227	0.62691158773378	2.4089297774851	0.015999376106631	0.21085326943571	0.21072053309777
1315	Cks2	27.6773	49.0936	-0.82683175162063	-0.80937761703912	-2.4085819823089	0.016014629011368	0.21089378752081	0.21072053309777
1316	Car6	0	5.39272	-5.914016878889	-5.8965627443075	-2.4084816414558	0.016019031935195	0.21079147114116	0.21072053309777
1317	Ugt1a6b	13.4134	3.79271	1.822374005931	1.8398281405125	2.408327232217	0.016025809440998	0.21072053309777	0.21072053309777
1318	St3gal5	5.36026	16.4624	-1.6187997913575	-1.601345656776	-2.4055892802902	0.016146406098561	0.21214515509013	0.21214515509013
1319	Dnaja2	52.5593	81.0215	-0.62435873319963	-0.60690459861812	-2.4030491461824	0.016259002150236	0.21346257788904	0.21346257788904
1320	Bzw2	41.8222	67.4696	-0.68996865377038	-0.67251451918887	-2.4024664345476	0.01628492898844	0.21364099643395	0.21364099643395
1322	Lamc1	46.3756	26.4526	0.8099564168258	0.82741055140731	2.4001213109903	0.01638963923479	0.21468939684482	0.2145806461326
1323	Rgs16	7.13118	19.4149	-1.4449515513796	-1.4274974167981	-2.4000299959407	0.016393728407543	0.2145806461326	0.2145806461326
1324	Hist2h2ac	28.2006	49.6916	-0.81727613746115	-0.79982200287964	-2.3985672916573	0.016459351938199	0.21527688633973	0.21527688633973
1326	Rarres1	13.7994	4.04276	1.7711930746493	1.7886472092308	2.3959371438301	0.016577932935601	0.21650080290031	0.21650080290031
1327	Ube2l6	22.6101	9.43544	1.2608056715928	1.2782598061743	2.3944355923139	0.016645966720608	0.21722547528317	0.21722547528317
1328	Car5b	16.7917	5.78274	1.5379231537024	1.555377288284	2.3930930558696	0.016707003166267	0.21785781161916	0.21782747466623
1329	Cox6b2	11.3418	2.73789	2.0505132314974	2.0679673660789	2.3926761514796	0.016725997054076	0.21794137771665	0.21782747466623
1331	Srsf1	32.4448	55.2145	-0.76705991322388	-0.74960577864237	-2.390324501995	0.016833492136078	0.21901245929411	0.21901245929411
1334	Srprb	19.1775	37.2982	-0.95969134682767	-0.94223721224616	-2.3883663037102	0.016923464608325	0.21968788352501	0.21968788352501
1335	Tbx15	58.2247	35.7762	0.70263114261081	0.72008527719232	2.3844293202761	0.017105633549381	0.22188633421321	0.22182914409772
1336	Arl14ep	18.9442	36.9337	-0.9631815811124	-0.94572744653089	-2.384028336531	0.017124283733463	0.22196199207513	0.22182914409772
1337	Nfix	25.7151	11.5555	1.1540360782434	1.171490212825	2.3839733099916	0.017126844468364	0.22182914409772	0.22182914409772
1338	Agfg1	16.8628	33.9858	-1.0110879732938	-0.99363383871224	-2.3828857933013	0.017177522513114	0.22231925064245	0.22231925064245
1340	Cdc42ep5	28.2605	13.3399	1.0830391391595	1.100493273741	2.3767827797478	0.017464369298017	0.22569439039833	0.22569439039833
1341	Maob	11.2169	2.71629	2.0459645955322	2.0634187301137	2.376103459109	0.017496556245893	0.22594173341546	0.22594173341546
1342	Hist1h2ai	9.7032	23.3406	-1.2663091332887	-1.2488549987071	-2.3745796226592	0.017568946508262	0.22670748635139	0.22670748635139
1343	Eif4e	27.4945	48.4806	-0.81826450306565	-0.80081036848414	-2.3716803257704	0.017707403654844	0.22832398294188	0.22821676977414
1344	Hsd3b7	25.8449	11.7051	1.1427423603114	1.1601964948929	2.3715788356812	0.017712267631602	0.22821676977414	0.22821676977414
1345	Porcn	26.8021	12.363	1.1163171738015	1.133771308383	2.3709224368272	0.017743754247195	0.22845248498043	0.22845248498043
1346	Slc35b1	49.1282	76.3142	-0.63540014701101	-0.6179460124295	-2.3700821656667	0.017784132560964	0.22880224632854	0.22870128428749
1347	Maff	7.45633	19.752	-1.4054611247144	-1.3880069901329	-2.3699707652853	0.0177894918251	0.22870128428749	0.22870128428749
1348	Abcg2	41.8858	23.2732	0.84779163768681	0.86524577226832	2.3696924428995	0.017802887579879	0.22870371232995	0.22870371232995
1350	Pakap	13.7099	29.297	-1.0955348927299	-1.0780807581484	-2.3655645157722	0.018002606357066	0.23092676613726	0.23092676613726
1351	Snrpf	38.2051	62.4033	-0.70785708691985	-0.69040295233834	-2.3646167815184	0.018048736014485	0.23134712180817	0.23124550886123
1352	Hsd17b12	41.8215	67.0244	-0.68044159171842	-0.66298745713691	-2.3645054386046	0.018054162267159	0.23124550886123	0.23124550886123
1353	Ly75	3.79577	13.4102	-1.8208662719925	-1.803412137411	-2.360994013514	0.018226024831085	0.23327425868433	0.23327425868433
1355	Zcchc5	8.03062	1.24518	2.6891570649593	2.7066111995408	2.3590457118719	0.018321998686336	0.23415649538839	0.23409227360023
1356	Fads3	49.8228	77.0435	-0.62886714257082	-0.61141300798931	-2.3588737335002	0.018330491597962	0.23409227360023	0.23409227360023
1358	Nmrk1	6.79505	18.5919	-1.4521181421479	-1.4346640075664	-2.3574711495643	0.018399885005599	0.23463240695284	0.2346043062237
1360	1110012L19Rik	46.9417	27.2213	0.78613412333263	0.80358825791414	2.3549046765163	0.018527457787003	0.23591175477759	0.23580910003459
1361	Tapbp	34.3388	17.7887	0.94887854179821	0.96633267637972	2.3546655890504	0.018539381529713	0.23589013221898	0.23580910003459
1362	Rassf2	20.4068	8.17912	1.3190324348376	1.3364865694191	2.3545203100562	0.01854663014651	0.23580910003459	0.23580910003459
1363	Hyou1	23.9024	43.4735	-0.86298076588624	-0.84552663130473	-2.3529669469899	0.018624289511625	0.23662275970125	0.23662275970125
1364	Snrnp70	47.6288	74.1571	-0.63875062610318	-0.62129649152167	-2.3476475052752	0.018892390997784	0.23985303145794	0.23985303145794
1365	Mars	24.022	43.5705	-0.85899539869196	-0.84154126411045	-2.3461073306571	0.018970643700071	0.24067006370266	0.24067006370266
1366	Tmtc4	5.90022	17.025	-1.5288141442449	-1.5113600096634	-2.3451657776687	0.019018621289686	0.24110209727196	0.24110209727196
1368	Fgd3	2.41234	10.634	-2.1401792085422	-2.1227250739607	-2.3414946455633	0.019206701457805	0.24313044528129	0.24313044528129
1369	Cmtm7	29.3029	50.5377	-0.78631655796634	-0.76886242338483	-2.3377799458455	0.019398666446753	0.24538108609088	0.24536764107826
1371	Plekho1	13.6507	28.9877	-1.0864659351392	-1.0690118005577	-2.3369196326518	0.01944336330742	0.24558768956572	0.24558768956572
1374	Pcdh9	8.41743	1.46172	2.5257128364545	2.543166971036	2.3345386058358	0.019567537027001	0.24661647648951	0.24661647648951
1376	Pparg	22.9494	9.93399	1.2080112360217	1.2254653706032	2.3339566693409	0.019597990925631	0.24664128550811	0.24664128550811
1377	Mthfd1l	8.90896	21.8163	-1.2920775126196	-1.2746233780381	-2.3326609352661	0.019665948026838	0.24731679156191	0.24731679156191
1378	Tmem64	6.37628	17.7327	-1.4756253307212	-1.4581711961397	-2.3305638738828	0.019776368278955	0.24852494157232	0.24852494157232
1379	Jade2	9.40312	1.9275	2.2864086691695	2.303862803751	2.3299072902518	0.019811051633223	0.24878026188	0.24878026188
1381	Smim1	18.7892	7.27871	1.3681489510059	1.3856030855874	2.3224517534859	0.020208623416656	0.25340530898351	0.25340530898351
1382	Calhm2	24.7342	11.1958	1.143549617718	1.1610037522995	2.3213478171798	0.020268079449475	0.25396695501198	0.25396695501198
1383	Mir6244	63.0963	40.2204	0.6496279776891	0.6670821122706	2.3206953482436	0.020303291968104	0.25422422777415	0.25422422777415
1389	Arhgdib	79.8233	53.9736	0.5645560057554	0.58201014033691	2.3112034055933	0.020821622352074	0.25958821761761	0.25942986240022
1391	Wars	26.825	46.9883	-0.80872340212145	-0.79126926753994	-2.310890877098	0.020838883097459	0.25942986240022	0.25942986240022
1393	Ndrg1	16.4741	5.88875	1.484166319206	1.5016204537875	2.3098465439707	0.020896651436615	0.25977552974002	0.25961172190211
1394	Zwint	45.8732	71.4941	-0.64017263967879	-0.62271850509728	-2.3098137763584	0.020898466266186	0.25961172190211	0.25961172190211
1395	Adamts6	2.22705	10.0991	-2.1810208763926	-2.1635667418111	-2.3093460021248	0.020924388857162	0.25974741350501	0.25974741350501
1396	Iah1	63.2742	40.4691	0.64479659690894	0.66225073149045	2.3090658542146	0.020939927194811	0.25975409687145	0.25975344566495
1397	Abcc5	29.5375	14.6044	1.0161446357893	1.0335987703709	2.3087965312563	0.020954874608416	0.25975344566495	0.25975344566495
1398	Hspb2	12.3163	3.48292	1.8221996732185	1.8396538078	2.3075866483507	0.021022137827493	0.2604008302995	0.2604008302995
1400	Pfdn4	28.8519	49.6262	-0.78243565957504	-0.76498152499354	-2.3064584172663	0.02108503106627	0.26080677355328	0.26070462846874
1401	Mir1966	5.93006	0	3.5680467019491	3.5855008365306	2.3060671093838	0.021106882780688	0.26079763761197	0.26070462846874
1402	Mir6387	5.93006	0	3.5680467019491	3.5855008365306	2.3060671093838	0.021106882780688	0.26079763761197	0.26070462846874
1403	Capn1	32.8155	16.9989	0.94893602269612	0.96639015727763	2.3019582465249	0.021337526933921	0.26336561219865	0.2633085784543
1405	Six1	27.9894	13.5512	1.0464599483682	1.0639140829497	2.3012743847961	0.021376126677954	0.26346646667768	0.26346646667768
1406	Wdr75	21.924	40.2899	-0.8779071849059	-0.86045305032439	-2.2992044436206	0.021493332810388	0.26472264884601	0.26472264884601
1407	Ptgfr	12.4089	3.56383	1.799874807005	1.8173289415865	2.2970058793351	0.021618434343418	0.26607421998931	0.2660349314659
1408	Fkbp11	47.5416	73.425	-0.62708090293191	-0.6096267683504	-2.2967925842307	0.021630604810532	0.2660349314659	0.2660349314659
1409	Ece1	63.3711	40.6736	0.63973236948274	0.65718650406424	2.2951758217825	0.02172305022183	0.26698229999391	0.26693144719074
1410	Iigp1	7.81222	1.2705	2.620336202154	2.6377903367355	2.2947888577219	0.021745227505925	0.26706532249652	0.26693144719074
1411	Dmkn	4.98001	0	6.8063064833051	6.8237606178866	2.2947101381929	0.021749741409374	0.26693144719074	0.26693144719074
1412	Ch25h	1.14099	7.63328	-2.742016965045	-2.7245628304635	-2.2940887467076	0.021785401623231	0.2671797449784	0.26703379818721
1413	Cyp20a1	42.1403	66.6066	-0.66046455514427	-0.64301042056276	-2.2940274564137	0.021788921686119	0.26703379818721	0.26703379818721
1415	Hmga2	26.6158	12.6322	1.0751770124423	1.0926311470238	2.2932264813696	0.02183496931244	0.2672199035926	0.2672199035926
1416	Mirlet7d	29.2614	49.9622	-0.77183820865656	-0.75438407407505	-2.2863888348745	0.02223152093551	0.27188082488716	0.27188082488716
1418	Ccdc28b	15.8924	5.62688	1.4979299089419	1.5153840435234	2.2840397197848	0.022369196708561	0.27317868787175	0.27317868787175
1419	Chsy1	24.791	44.0131	-0.82811652257678	-0.81066238799527	-2.2836588081555	0.02239159069246	0.2732594616077	0.2732594616077
1420	Scp2	69.0103	45.3638	0.60527020872989	0.62272434331139	2.2831227169301	0.022423140779687	0.27345178090271	0.27340730413311
1421	Khk	9.16256	1.9152	2.2582556832106	2.2757098177921	2.2829165902934	0.022435282044993	0.27340730413311	0.27340730413311
1422	Naga	35.8039	19.3318	0.88914076969143	0.90659490427294	2.2792110698771	0.022654521370741	0.27588491320473	0.27585516741996
1423	Hist1h2an	6.67927	17.9123	-1.4231882567393	-1.4057341221578	-2.2787164114835	0.022683928532294	0.27604890400123	0.27585516741996
1424	Eif2s1	45.5196	70.674	-0.6346916846954	-0.61723755011389	-2.2784768623871	0.022698181508359	0.27602837723332	0.27585516741996
1425	Prodh	5.4052	0	3.9404998509869	3.9579539855684	2.2784485268159	0.022699867966359	0.27585516741996	0.27585516741996
1427	Wdr43	18.8407	35.8319	-0.92739197775128	-0.90993784316977	-2.2733901980691	0.023002676302641	0.27914319939232	0.27914319939232
1428	Rnf149	20.9243	38.6832	-0.88652778440428	-0.86907364982277	-2.2720664706102	0.023082495877967	0.27991567305235	0.27991567305235
1429	Slc4a7	6.07764	16.8808	-1.4738001499969	-1.4563460154154	-2.2717649033085	0.02310071371977	0.27994055947184	0.27994055947184
1430	Rilpl1	26.5656	12.7155	1.0629711043876	1.0804252389691	2.2702659789707	0.023191449928472	0.28084359329465	0.28084359329465
1431	Tgfa	4.72946	0	5.9640001163046	5.9814542508861	2.2682525519515	0.023313818072527	0.28212815343253	0.28212815343253
1434	Il4ra	25.792	45.1795	-0.80874465558355	-0.79129052100204	-2.2660267183872	0.023449747413541	0.28317941140885	0.28310498026704
1435	Susd2	6.01762	0	3.3503132304647	3.3677673650462	2.2658603938489	0.0234599322448	0.28310498026704	0.28310498026704
1436	Cdc20	14.0929	29.0685	-1.0444881108865	-1.027033976305	-2.2646951424673	0.023531393778776	0.28376960032526	0.28376960032526
1437	Slmo2	37.4314	60.2917	-0.68771039997147	-0.67025626538996	-2.264330806578	0.023553776188702	0.28384185265118	0.28384185265118
1438	Rhou	23.2596	10.4705	1.1514959494739	1.1689500840554	2.2633748369695	0.023612592553399	0.28435275747372	0.28435275747372
1439	Agmo	9.04792	1.907	2.2462813296963	2.2637354642779	2.2613404305292	0.023738184446412	0.28566653235477	0.28566653235477
1440	Sox11	0	5.70186	-3.6596735825804	-3.6422194479989	-2.2608477442718	0.023768686927568	0.2858349663366	0.28567251868279
1441	Rnf4	45.3827	70.291	-0.63119753635896	-0.61374340177745	-2.2607995062181	0.023771675199047	0.28567251868279	0.28567251868279
1442	Mir1668	6.17688	16.969	-1.4579513395056	-1.4404972049241	-2.2591008233898	0.023877113946386	0.28674062566544	0.28642480392202
1443	Serpinb1a	22.0397	9.66735	1.188912206836	1.2063663414175	2.2590474642383	0.02388043255683	0.28658173983827	0.28642480392202
1444	Ajuba	7.61553	19.2951	-1.3412181717526	-1.323764037171	-2.2589917926537	0.023883895412796	0.28642480392202	0.28642480392202
1447	Tns2	17.8054	6.9167	1.3641590578771	1.3816131924587	2.2558809783037	0.024078086100278	0.28815495300519	0.28815495300519
1448	Pxdn	14.5142	29.6007	-1.0281662381769	-1.0107121035954	-2.2553842411075	0.024109221037136	0.28832830158845	0.28820609725223
1450	Pi15	11.605	3.24058	1.8404225673496	1.8578767019311	2.255016572682	0.024132288561283	0.28820609725223	0.28820609725223
1451	Thbs4	6.67236	0	2.9537249745963	2.9711791091778	2.2547251695726	0.024150584789004	0.28822582825029	0.28822582825029
1454	Ipmk	16.4994	6.12283	1.4301430294583	1.4475971640398	2.2494151114439	0.024486098067379	0.29162707031142	0.29162707031142
1455	Lnx1	9.74537	2.28004	2.0956578263537	2.1131119609352	2.2486571859329	0.024534315086657	0.29200050471178	0.29200050471178
1456	Pcx	14.5753	4.96251	1.5543836638275	1.571837798409	2.2467455279749	0.024656294800958	0.29325072600837	0.29325072600837
1457	Rhbdd1	10.4582	23.5895	-1.1735102744232	-1.1560561398417	-2.2456443102143	0.024726799893795	0.2938874356629	0.2938874356629
1458	Rnf7	48.5529	74.0332	-0.60861492029885	-0.59116078571734	-2.2435954895993	0.024858439733045	0.29524938330394	0.29498218119429
1459	C430002N11Rik	1.74575	8.78145	-2.3306122056593	-2.3131580710778	-2.2434052821302	0.024870691584711	0.295192437404	0.29498218119429
1461	Sema3b	12.6436	3.85109	1.7150685547353	1.7325226893168	2.2431515175555	0.024887045488529	0.29498218119429	0.29498218119429
1462	Pappa	26.9888	46.5072	-0.7850932521244	-0.76763911754289	-2.2395243869205	0.025121816378174	0.29756121355734	0.29756121355734
1463	Abat	12.6267	3.85392	1.7120791092027	1.7295332437843	2.2389434668822	0.025159594779048	0.29780499165329	0.29780499165329
1464	Tmem100	11.9551	3.47977	1.7805623402104	1.7980164747919	2.2381312740489	0.025212495754036	0.29822731487202	0.29822731487202
1465	Nr4a1	3.29516	11.8298	-1.8440052593833	-1.8265511248018	-2.2369754209103	0.025287946523037	0.29891561088015	0.29891561088015
1466	Aplp1	4.87062	14.6255	-1.586308611436	-1.5688544768545	-2.2339467773928	0.025486575197952	0.30105799638672	0.30105799638672
1467	Arap1	25.7699	12.3638	1.0595647167432	1.0770188513247	2.2302734227111	0.025729296466679	0.30371794608963	0.30371794608963
1468	Gm4951	5.60885	0	3.5145037257442	3.5319578603257	2.2298440554103	0.02575779750217	0.30384726113425	0.30384726113425
1469	Tspan2	2.08059	9.41799	-2.1784264944527	-2.1609723598712	-2.2284396168001	0.025851213746012	0.30474163950966	0.30474163950966
1470	Nupl1	17.7932	33.9856	-0.93359759918632	-0.91614346460481	-2.2267473777615	0.025964162084371	0.30586489443201	0.30586489443201
1471	Mir8113	5.61899	0	3.4903108327699	3.5077649673515	2.2258832534292	0.026022002368477	0.30633787560498	0.30633787560498
1472	Alg5	34.9381	56.6781	-0.69799024220719	-0.68053610762568	-2.2251264759234	0.026072748839795	0.30672676063772	0.30672676063772
1474	Sh3d19	29.4097	14.9897	0.97232055793026	0.98977469251177	2.2229341411176	0.026220241204147	0.30804336291194	0.30804336291194
1475	Snhg5	28.6995	48.5866	-0.75953287624674	-0.74207874166523	-2.2226491111239	0.026239469862138	0.30806027091705	0.30806027091705
1478	Il11ra1	26.3748	12.8492	1.0374816148777	1.0549357494592	2.2185084402097	0.026520184748891	0.31072397787317	0.31072397787317
1479	Kcnab1	9.92306	2.44289	2.0221961743893	2.0396503089709	2.2182408059845	0.026538417817315	0.31072737075216	0.31072737075216
1482	Rbms2	32.1019	17.0117	0.91613136949853	0.93358550408004	2.2120433677774	0.026963668552605	0.31506737403878	0.31506737403878
1488	Nrip2	8.83218	1.92192	2.2002212894483	2.2176754240298	2.2062981041406	0.027363134048377	0.31844582816918	0.31844582816918
1490	Bok	17.3573	33.1962	-0.93547555633748	-0.91802142175597	-2.204527518649	0.02748726683777	0.31946107371118	0.31946107371118
1491	Syncrip	39.2968	61.9369	-0.65638734022902	-0.63893320564751	-2.1996731028239	0.027830096456964	0.32322855824631	0.32322855824631
1492	Ccna2	15.5347	30.6012	-0.97809384711364	-0.96063971253213	-2.1985706438021	0.027908466266674	0.3239215216756	0.3239215216756
1493	Hrct1	11.3165	3.24068	1.8040593519417	1.8215134865232	2.1970266177079	0.028018545262068	0.32498134514617	0.32498134514617
1495	Gys1	11.472	24.7332	-1.1083319796197	-1.0908778450382	-2.1944433581227	0.028203551756014	0.3266895690695	0.3266895690695
1497	Irgm2	13.2469	4.35476	1.6049896678222	1.6224438024037	2.1915707899354	0.028410513029486	0.3286471971487	0.32848948979402
1498	Uqcrq	40.8822	63.8404	-0.64299685664401	-0.6255427220625	-2.191496967911	0.02841584891791	0.32848948979402	0.32848948979402
1500	Mir6538	5.47481	0	3.4528088977158	3.4702630322973	2.1878219870977	0.028682571649331	0.33102038870474	0.33091012208625
1501	Mir6539	5.47481	0	3.4528088977158	3.4702630322973	2.1878219870977	0.028682571649331	0.33102038870474	0.33091012208625
1502	G6pdx	52.6304	32.9994	0.67345656618657	0.69091070076808	2.1861593816746	0.028803946796506	0.33208917887822	0.33208917887822
1503	Pdlim2	65.0765	43.0937	0.59465968811516	0.61211382269667	2.1833258289774	0.029011823754634	0.33426330802329	0.33426330802329
1504	Lxn	48.0918	29.4454	0.70774865311906	0.72520278770057	2.1804938253327	0.029220876041901	0.33644807873511	0.33644807873511
1507	Tlr4	31.3937	16.6963	0.91094664388888	0.92840077847039	2.1773136466611	0.029457173668811	0.33849361408282	0.33849361408282
1508	Srgn	5.27282	0	3.5724603291465	3.589914463728	2.1755343236767	0.029590098884734	0.33979558513723	0.33979558513723
1511	Mndal	10.3945	2.80388	1.8903238512717	1.9077779858532	2.1726226040748	0.02980873318984	0.34162662650461	0.34162662650461
1512	Snx33	25.8311	12.7064	1.0235537396678	1.0410078742493	2.1717711580587	0.029872928182656	0.34213591093852	0.34213591093852
1513	Reck	15.9394	6.05725	1.3958624617246	1.4133165963061	2.1714161796509	0.029899726955578	0.34221650475198	0.34221650475198
1515	Inhbb	30.5387	16.1347	0.92047189607474	0.93792603065625	2.1659134510905	0.030317801239227	0.34654347462686	0.34654347462686
1517	Angpt4	22.1359	39.3597	-0.83033119285349	-0.81287705827198	-2.1646290163137	0.030416107054251	0.34720878434968	0.34720878434968
1518	Galm	17.6479	7.17208	1.2990330354267	1.3164871700083	2.1643039350957	0.030441030928625	0.34726438247101	0.34726438247101
1519	Ly6e	49.2422	30.4841	0.69183826564159	0.7092924002231	2.1639715562856	0.030466532444229	0.3473264926509	0.3473264926509
1523	Tbc1d2b	46.9751	28.7566	0.70800312219122	0.72545725677273	2.1556895153424	0.03110791741657	0.35370702948309	0.35370702948309
1525	Acp5	6.0641	0	2.9619026968373	2.9793568314188	2.1523616999166	0.031368877773635	0.35620646321708	0.35620646321708
1526	C1qtnf7	6.22739	0	2.8755424548087	2.8929965893902	2.1498581068682	0.031566440252865	0.35821497107396	0.35821497107396
1528	Epb4.1l3	38.137	59.89	-0.65112377202562	-0.63366963744411	-2.1471568363909	0.031780797726171	0.36017544124614	0.36017544124614
1529	Masp1	31.8005	17.1789	0.8884117884873	0.90586592306881	2.1465508096403	0.031829059613255	0.36048647830134	0.36048647830134
1530	Mapkapk2	39.5623	61.6718	-0.64048465324628	-0.62303051866477	-2.1462356099083	0.031854185866982	0.360535252718	0.36051361767753
1533	Ccpg1	20.7473	9.31145	1.155845849954	1.1732999845355	2.1439837571238	0.032034188278338	0.36186303875797	0.36186303875797
1534	Ptprg	19.6352	8.56545	1.1968413452969	1.2142954798784	2.1433260307259	0.03208692803654	0.36222251160937	0.36222251160937
1535	Samd4	10.0102	22.2085	-1.149641155128	-1.1321870205465	-2.1427751678157	0.032131156198463	0.36248549308716	0.36248549308716
1536	Mir8114	5.30561	0	3.4075186311367	3.4249727657183	2.1423887195469	0.032162214868287	0.36259965812118	0.36259965812118
1538	Slc25a24	27.5295	46.2503	-0.74848431615963	-0.73103018157812	-2.140357620657	0.032325876649311	0.36397087512102	0.3638024890339
1541	Gm24148	3.3432	11.4166	-1.7718314939452	-1.7543773593637	-2.1372911469625	0.032574318476464	0.36605416810962	0.36605416810962
1542	4930486L24Rik	6.43007	0	2.7488708774676	2.7663250120491	2.1352706244415	0.032738910968355	0.36766518887095	0.36766518887095
1543	Mut	27.3789	14.0104	0.96656633909304	0.98402047367455	2.1344687593912	0.032804428303692	0.36816220669802	0.36816220669802
1544	Ppp1r15a	11.4444	24.2461	-1.0831108794388	-1.0656567448573	-2.1317899789979	0.03302411581836	0.370387703126	0.370387703126
1545	Dpt	5.51928	0	3.2103432219608	3.2277973565423	2.1308846242216	0.033098648395483	0.37098336198354	0.37095233269763
1546	Gnl3	30.9459	50.5719	-0.70858770145366	-0.69113356687214	-2.1306583187029	0.033117301284895	0.37095233269763	0.37095233269763
1547	Ezh1	14.6122	5.37841	1.4419217632137	1.4593758977953	2.129737440811	0.033193296069496	0.37156322432803	0.37156322432803
1548	Ggta1	36.2271	20.6144	0.81341685090723	0.83087098548874	2.1289012379524	0.033262432344936	0.37209660265973	0.37192459548644
1550	Cab39l	32.1895	17.582	0.87249097731076	0.88994511189226	2.127545573302	0.03337477893144	0.37287164306823	0.37287164306823
1551	Mrto4	26.3925	44.6323	-0.75796013892635	-0.74050600434484	-2.126344020229	0.033474625231235	0.37374602522843	0.37374602522843
1552	Ltbp2	35.2141	55.9545	-0.66810095011015	-0.65064681552864	-2.1247511477377	0.033607383111092	0.37498650343736	0.37497059712821
1553	Nup88	22.2002	39.0837	-0.81599437795276	-0.79854024337125	-2.1242532977003	0.033648968660563	0.37520875099483	0.37497059712821
1554	Dclk1	33.9078	18.8893	0.84404794341078	0.86150207799229	2.1242497616202	0.033649264187632	0.37497059712821	0.37497059712821
1555	Fam214a	17.4674	7.21379	1.2758355502537	1.2932896848352	2.1237863553713	0.033688012469626	0.37516097230644	0.37516097230644
1556	Kng2	17.703	7.37078	1.2641046609612	1.2815587955427	2.1229791741942	0.033755597040112	0.37567202695606	0.37567202695606
1557	Cxcl1	6.41377	16.5393	-1.3666536517115	-1.34919951713	-2.1222701155743	0.033815061524429	0.37609211330671	0.37609211330671
1559	Utp11l	33.2291	53.3977	-0.68433038341853	-0.66687624883702	-2.1214356422775	0.033885158501676	0.37638825514659	0.37614820816947
1560	Pld1	11.3545	3.47096	1.7098575332996	1.7273116678811	2.1212459344325	0.033901111559336	0.3763240697904	0.37614820816947
1562	Mnda	14.0642	5.07315	1.4710737685943	1.4885279031758	2.1204184979169	0.033970768091999	0.37661446289958	0.37661446289958
1564	Ggt5	7.42476	1.42669	2.3796725014008	2.3971266359823	2.1196257527212	0.034037618919768	0.37687304784758	0.37687304784758
1566	Camk2g	25.6732	43.5982	-0.76400544314755	-0.74655130856604	-2.1165040071767	0.034301964757927	0.37931489381419	0.37920605893321
1569	Pno1	23.7669	41.0818	-0.78954565497203	-0.77209152039052	-2.1154173302074	0.034394394028475	0.37960976506763	0.37947483958489
1570	Pxylp1	19.2693	35.0694	-0.86390858433677	-0.84645444975527	-2.1153035678308	0.034404082586376	0.37947483958489	0.37947483958489
1571	Adh1	5.76947	0	3.0029491812103	3.0204033157918	2.113262118018	0.034578339165716	0.38115410524042	0.38115410524042
1572	1190002N15Rik	25.8338	13.0144	0.98915106999284	1.0066052045744	2.1126668837411	0.034629289650686	0.3814729064128	0.3814729064128
1573	Aldh3b1	18.8247	8.15495	1.2068789369985	1.22433307158	2.1122935273973	0.034661280684397	0.381582579537	0.38157534710823
1574	Mir218-1	5.47481	14.9568	-1.4499207415176	-1.4324666069361	-2.1120441988967	0.03468265844825	0.38157534710823	0.38157534710823
1576	Yrdc	11.0917	23.5695	-1.0874406527045	-1.069986518123	-2.1087915849661	0.034962575291023	0.38416682507274	0.38416682507274
1577	C130074G19Rik	5.9333	0	2.8940468880288	2.9115010226103	2.1051416194464	0.035278982311722	0.38739767704001	0.38739767704001
1579	As3mt	10.5162	3.04903	1.7861912344152	1.8036453689967	2.103643053678	0.035409595368917	0.38833943192118	0.38833943192118
1581	Dapk1	14.8691	5.63724	1.3992564310505	1.416710565632	2.1010458061265	0.035636945461348	0.39033838365223	0.39033838365223
1583	4930562F07Rik	10.0918	2.82532	1.83669733657	1.8541514711515	2.1000032647304	0.035728553937454	0.39084735851856	0.3907364678432
1585	Galnt16	7.34969	1.43341	2.3582320758645	2.375686210446	2.0978002754242	0.035922792189396	0.39247633586358	0.39247633586358
1586	Klhl24	25.5079	12.8651	0.9874814593094	1.0049355938909	2.0964228623776	0.036044696069319	0.39355990027263	0.39332166051206
1589	Ak2	33.6952	53.7177	-0.67285444598966	-0.65540031140815	-2.0953300093106	0.036141666573068	0.3938736564165	0.3938736564165
1590	Izumo4	20.0164	9.03073	1.148268007228	1.1657221418096	2.0950280711753	0.036168497177745	0.39391815448239	0.39391815448239
1591	Magohb	16.608	31.2608	-0.91247635023498	-0.89502221565347	-2.0940302852985	0.036257282491402	0.39463693331465	0.39463693331465
1595	Ctla2b	8.89892	2.22245	2.0014792947357	2.0189334293172	2.0867950844067	0.036906661676295	0.40069759263223	0.40069759263223
1596	Mir1188	0	5.16722	-3.3693883093777	-3.3519341747962	-2.0828933537105	0.037260945574196	0.40429059806288	0.40429059806288
1598	Gnpnat1	18.4453	33.6695	-0.86818904330681	-0.8507349087253	-2.0815897468831	0.037379958740829	0.40507430883288	0.40507430883288
1600	Lnpep	48.8102	30.8036	0.66408369543348	0.68153783001499	2.0801350180445	0.037513150463039	0.40600951660528	0.40600951660528
1601	Ttc39c	15.9486	6.40406	1.3163710571712	1.3338251917527	2.0783094610004	0.037680865611801	0.40756998738261	0.40743078141256
1602	Zyx	37.3792	58.1818	-0.63833223806613	-0.62087810348462	-2.0781936854912	0.037691523463817	0.40743078141256	0.40743078141256
1603	Tbl1xr1	30.0504	16.286	0.88375188729891	0.90120602188042	2.0775902018062	0.037747119407272	0.40777720946708	0.40777720946708
1604	Cd302	49.8797	31.6864	0.65458902862111	0.67204316320262	2.0769216966258	0.037808786886664	0.40818875468601	0.40797362313046
1605	Dcaf6	28.2507	14.961	0.91708000644382	0.93453414102533	2.0768823483834	0.037812419306138	0.40797362313046	0.40797362313046
1606	Trpm3	4.62179	0	3.7673167286851	3.7847708632666	2.0760633019753	0.037888096722847	0.40853559834965	0.40853559834965
1608	Trafd1	36.8751	21.4712	0.78024413777862	0.79769827236013	2.0739919994469	0.038080053896228	0.41009470977673	0.41009470977673
1609	Nexn	4.06154	12.3621	-1.6058250825931	-1.5883709480115	-2.0723532284411	0.038232511801353	0.41148067549038	0.41148067549038
1610	4632428N05Rik	9.61328	2.64113	1.8638734402078	1.8813275747893	2.0698810238534	0.038463487380537	0.41370944780668	0.41370944780668
1612	E030011O05Rik	16.0741	30.3272	-0.9158743430089	-0.89842020842739	-2.0691352461636	0.038533397073997	0.41394716943573	0.41394716943573
1613	Igf1	7.92398	1.7681	2.1640253660726	2.1814795006541	2.0686118116639	0.038582528641366	0.41421800897863	0.41417162493504
1614	Ube2c	14.6194	28.304	-0.95312185079644	-0.93566771621493	-2.0684031928767	0.038602125232151	0.41417162493504	0.41417162493504
1615	Jmjd6	14.6505	28.3444	-0.95211382767385	-0.93465969309234	-2.0680101443925	0.038639069194376	0.41431130726873	0.41424399585496
1617	Ip6k1	31.4401	17.388	0.85451380558527	0.87196794016678	2.0665876613573	0.038773024444019	0.41523343493944	0.41523343493944
1618	Fam160a1	17.0108	7.1428	1.2518893598011	1.2693434943826	2.0655917646564	0.0388670426994	0.41598305217893	0.41598305217893
1620	Pole4	14.4148	27.9862	-0.95716478922214	-0.93971065464063	-2.0641984266203	0.03899890664098	0.41687905327275	0.41687905327275
1621	Pdk4	55.1278	36.0491	0.61281678689268	0.63027092147419	2.0626163130096	0.039149096611145	0.41822634547514	0.41819243475909
1623	Fam53b	10.708	3.27409	1.7095231590209	1.7269772936024	2.0596916013015	0.039428032838814	0.42068715013539	0.4203524801289
1625	Fat4	18.9365	8.45126	1.1639313504299	1.1813854850115	2.059512022133	0.039445214541171	0.4203524801289	0.4203524801289
1627	Dusp4	2.90582	10.2248	-1.8150553803039	-1.7976012457224	-2.0570268438215	0.039683643796265	0.422373484708	0.42225701891953
1628	Olfml2a	6.61509	1.17098	2.4980443496392	2.5154984842207	2.0568871186525	0.039697085338164	0.42225701891953	0.42225701891953
1629	Sh3kbp1	26.5862	44.1886	-0.73299663814692	-0.71554250356541	-2.0532864880878	0.04004480054371	0.42569417496343	0.42569417496343
1633	Hist1h3d	7.24602	17.4227	-1.2657075231153	-1.2482533885337	-2.0508012583192	0.040286304979693	0.42721245764442	0.42721245764442
1634	Ppp1r12a	36.7044	57.0256	-0.63565670219971	-0.6182025676182	-2.0495238815275	0.040410915053978	0.42827161321281	0.42827161321281
1635	Bmp8a	5.14073	0	3.1843003294561	3.2017544640376	2.0491454164259	0.040447897607738	0.42840137178789	0.42840137178789
1636	Calml4	10.6897	3.29812	1.696505568873	1.7139597034545	2.0470310499993	0.040655035977239	0.43033206480309	0.43033206480309
1637	Fgf14	4.14702	0	4.3069633359015	4.3244174704831	2.0463458948473	0.040722351251595	0.43078128077206	0.43078128077206
1638	Wnk4	4.04544	0	4.52871972427	4.5461738588515	2.0446709968513	0.040887304841819	0.43226218433808	0.43226218433808
1639	Slfn5	9.44719	2.61462	1.853283988376	1.8707381229575	2.0441200925935	0.040941684662909	0.43257300384844	0.4323991623259
1641	Slc25a39	41.3466	62.7311	-0.60141216171129	-0.58395802712978	-2.0426252950283	0.041089545128481	0.43360612613645	0.43360612613645
1642	Agtrap	18.6157	8.30729	1.1640700427929	1.1815241773744	2.042182993844	0.041133382750156	0.43380437824875	0.43380437824875
1644	Apbb2	27.8361	14.8548	0.90602791400721	0.92348204858872	2.0411102731358	0.041239867494516	0.43439828795775	0.43420395041741
1646	Iqsec1	14.209	5.43225	1.3871832431285	1.40463737771	2.0406406610427	0.041286557464229	0.43436167412397	0.43436167412397
1648	Cacna1g	7.5946	1.66592	2.1886548594535	2.206108994035	2.0393041283065	0.041419683887339	0.43523341376035	0.43522112883368
1649	Sptssa	48.2082	30.6464	0.65356095130796	0.67101508588947	2.0390639316304	0.041443647366561	0.43522112883368	0.43522112883368
1650	Hist1h2ak	11.57	23.7674	-1.0385952259503	-1.0211410913688	-2.0381345068222	0.041536483068186	0.43593168320714	0.43593168320714
1651	Psd4	12.6738	4.49362	1.4958991200121	1.5133532545936	2.0376628226754	0.041583664610996	0.4361625197266	0.43614601796957
1652	Terc	23.6008	11.7994	1.0001222633278	1.0175763979093	2.0374269312087	0.041607277339362	0.43614601796957	0.43614601796957
1653	Slc35f5	33.6178	19.2177	0.80678963272982	0.82424376731133	2.0367782649076	0.041672267352603	0.43656300892016	0.43656300892016
1655	Rarres2	9.27464	2.54181	1.8674350907702	1.8848892253518	2.0356890686605	0.041781587460191	0.43717930516503	0.43717930516503
1657	Abhd14b	14.5918	5.69476	1.3574509133204	1.374905047902	2.0346295933519	0.041888157361024	0.43776537176877	0.43776537176877
1659	Gclm	11.0435	22.9649	-1.0562330256224	-1.0387788910409	-2.031814781018	0.042172410257541	0.44020471876422	0.44020471876422
1660	St6galnac6	31.0166	17.2909	0.84302758472351	0.86048171930502	2.0296187678245	0.042395305696229	0.44226476430217	0.44226476430217
1661	Rrn3	24.2594	40.9363	-0.7548368420474	-0.73738270746589	-2.0289060917291	0.042467856186857	0.44275488596496	0.44242328976105
1663	Mcpt8	2.46534	9.26875	-1.910588162267	-1.8931340276855	-2.0287167644765	0.042487147362281	0.44242328976105	0.44242328976105
1665	Ssfa2	17.806	7.82185	1.1867816861329	1.2042358207144	2.0276720376511	0.042593731344927	0.44300038780787	0.44300038780787
1666	Wwp2	11.5944	23.7211	-1.0327427486864	-1.0152886141049	-2.026532731101	0.042710222091818	0.44394532770949	0.44394532770949
1667	Hist1h4f	26.3047	43.5648	-0.72784232344719	-0.71038818886568	-2.0258644697795	0.042778675108216	0.44439011208697	0.44439011208697
1669	Dhx58	7.53634	1.66661	2.1769475115259	2.1944016461074	2.0247900848234	0.04288892363474	0.44500149226051	0.44500149226051
1670	Lbh	15.6529	29.3955	-0.90916534863784	-0.89171121405633	-2.0242428670499	0.042945168910554	0.44531825749944	0.44531825749944
1671	Slc7a1	4.61857	13.0557	-1.4991616727134	-1.4817075381319	-2.023744461379	0.042996451322612	0.44558321218054	0.44558321218054
1673	Mcee	26.2031	13.7631	0.92893204301794	0.94638617759945	2.0214105101542	0.043237287615697	0.44754340086134	0.44742005362636
1674	Irf7	12.2173	4.26849	1.5171277830134	1.534581917595	2.0212432620523	0.043254589333831	0.44745503195577	0.44742005362636
1675	Cpxm1	17.6298	7.73064	1.189356346945	1.2068104815265	2.0210262764057	0.043277045090036	0.44742005362636	0.44742005362636
1676	Ppan	13.9611	27.0253	-0.95289801650943	-0.93544388192792	-2.0207345971833	0.043307246373838	0.44746514645331	0.44746514645331
1677	Sfrp2	9.97245	2.96423	1.7502905916069	1.7677447261884	2.0202899558354	0.043353320048592	0.44767408663176	0.44767408663176
1679	Cxx1c	13.393	5.00168	1.4209944929886	1.4384486275701	2.0170151364609	0.043693933739575	0.45065387169042	0.45049654835804
1680	Efnb2	3.39266	10.9136	-1.6856383120544	-1.6681841774729	-2.0169120256797	0.043704694880263	0.45049654835804	0.45049654835804
1681	Tpx2	9.54045	20.6637	-1.1149693819752	-1.0975152473937	-2.0156843918379	0.043832988750844	0.45155018810134	0.45155018810134
1682	Bub3	32.5424	51.4261	-0.66018009460245	-0.64272596002094	-2.0149217151265	0.043912852317116	0.45210396169768	0.45210396169768
1683	Gnl3l	19.367	34.3502	-0.82671800505514	-0.80926387047364	-2.0144595481546	0.043961307811773	0.45233390812625	0.45233390812625
1684	Schip1	4.3802	12.5986	-1.524194775449	-1.5067406408675	-2.0128376176105	0.044131715049278	0.45381764222586	0.45381764222586
1687	Fxr2	23.6763	40.0143	-0.7570720290525	-0.73961789447099	-2.0112281511082	0.044301363583391	0.45475205285926	0.45475205285926
1689	Bdnf	7.04868	16.85	-1.2573235756989	-1.2398694411174	-2.0061799079797	0.044837056723451	0.45970592734162	0.45930192357059
1690	Irf9	25.9423	13.6536	0.92602500015857	0.94347913474008	2.0061577010655	0.044839425220744	0.45945818138912	0.45930192357059
1692	Serpinb6c	4.18467	0	3.9469827479358	3.9644368825173	2.0057959595394	0.044878021932403	0.4593101098129	0.4593101098129
1693	Parp9	21.0763	10.1652	1.0519830198449	1.0694371544264	2.0053986430742	0.044920446664834	0.45947275540161	0.45947275540161
1694	Emilin1	35.1273	54.5741	-0.63562374291066	-0.61816960832915	-2.0048884151976	0.044974977473398	0.45975896393555	0.45975896393555
1695	Aamdc	29.2374	16.1035	0.86044073855841	0.87789487313992	2.0043649580966	0.045030980161188	0.46005987224265	0.46005987224265
1696	Gm10638	11.1498	3.68711	1.5964554689104	1.6139096034919	2.0030114903783	0.045176055166363	0.46126989818155	0.46124978037949
1697	Cdk17	9.91089	21.1225	-1.0916940754916	-1.0742399409101	-2.0027817411314	0.045200720523416	0.46124978037949	0.46124978037949
1698	Gamt	23.4157	11.843	0.98344158489519	1.0008957194767	2.0019323496667	0.045292007856494	0.46190912841632	0.46190912841632
1700	Abhd5	31.6785	17.9687	0.81801798789299	0.8354721224745	2.0001949163457	0.045479220554665	0.46327274255596	0.46327274255596
1701	Rcan2	23.1814	11.6851	0.98829761738878	1.0057517519703	1.9998716439929	0.045514125805263	0.46335574166357	0.46335574166357
1702	Ereg	10.8296	22.4243	-1.0500829936559	-1.0326288590744	-1.9979986099303	0.045716810826143	0.46514571861123	0.46506189054078
1703	Pcmtd2	15.1383	6.17648	1.2933464228104	1.3108005573919	1.9978269214692	0.045735427590861	0.46506189054078	0.46506189054078
1704	Hebp1	30.6736	17.2245	0.83253539373161	0.84998952831312	1.9973825573105	0.045783641171051	0.46527894023421	0.46527894023421
1705	Sorbs2	12.7488	4.67007	1.4488453777666	1.4662995123481	1.9963519711363	0.045895624763498	0.46614342171818	0.46614342171818
1707	Ppapdc1b	23.5404	39.6819	-0.75334226977854	-0.73588813519703	-1.9940451556286	0.046147119972316	0.46814860958442	0.46814860958442
1708	Egln1	9.92544	21.0714	-1.0860832068869	-1.0686290723054	-1.9918453103113	0.046388033056611	0.47031707754176	0.47004634530331
1709	Aurka	6.50612	15.9231	-1.2912518982784	-1.2737977636969	-1.9918412928314	0.046388473992225	0.47004634530331	0.47004634530331
1710	1110008P14Rik	38.6801	23.4324	0.72308679873726	0.74054093331877	1.9915749983629	0.046417708819353	0.47006752258757	0.47006752258757
1711	Prkar2b	24.6426	12.7887	0.94628486194239	0.9637389965239	1.9902437535832	0.046564090652404	0.47127431784202	0.47127431784202
1712	Acvr1b	9.26055	2.64633	1.8071049018207	1.8245590364022	1.9897280122423	0.046620905184255	0.4715737237592	0.4712907756102
1713	Ikbkg	12.6696	24.9866	-0.97978362607613	-0.96232949149462	-1.9895732216673	0.046637968432686	0.471470927816	0.4712907756102
1714	Ruvbl2	16.8979	30.8218	-0.86710715245494	-0.84965301787343	-1.9894548316049	0.046651022638995	0.4713277473976	0.4712907756102
1715	Mphosph6	11.3303	23.0834	-1.0266696761885	-1.009215541607	-1.9892412691425	0.04667457874756	0.4712907756102	0.4712907756102
1719	Cth	2.34867	8.84795	-1.9134992112398	-1.8960450766583	-1.9841766285592	0.047236153012233	0.47585134480095	0.47576927389482
1720	Rrp9	13.578	26.2189	-0.94933616888786	-0.93188203430635	-1.984003226665	0.047255480227469	0.47576927389482	0.47576927389482
1721	Best1	4.58886	0	3.3699591866074	3.3874133211889	1.9834473037064	0.047317487733474	0.47611675484054	0.47611675484054
1722	Nek9	35.1235	20.7264	0.76096705995853	0.77842119454004	1.9818274531224	0.047498555737314	0.47766114384614	0.47750162982573
1723	Galnt9	3.74827	0	6.9670386293079	6.9844927638894	1.9817228544898	0.047510267840257	0.47750162982573	0.47750162982573
1726	Slc6a12	9.14864	2.61136	1.8087559339526	1.8262100685341	1.9788922074085	0.047828143811552	0.47986093069794	0.47986093069794
1728	Ccdc47	24.3512	40.5747	-0.73658755939402	-0.71913342481251	-1.9761741510364	0.048135056449655	0.48238123410803	0.48238123410803
1729	Antxr1	54.7512	36.4898	0.58539734152449	0.602851476106	1.9754977673471	0.048211687728753	0.48286974921852	0.48286974921852
1731	Mturn	8.7462	2.40268	1.8640118225253	1.8814659571068	1.9744253198261	0.048333401354455	0.48352946924038	0.48335220343802
1732	Mzt1	19.9106	34.7368	-0.80292816029376	-0.78547402571225	-1.9743356134763	0.048343593945525	0.48335220343802	0.48335220343802
1733	Fbl	32.0924	50.4367	-0.65224220106548	-0.63478806648397	-1.9735123722757	0.048437216376033	0.4840088147627	0.4840088147627
1734	Pygl	25.4282	13.4553	0.91825478306066	0.93570891764217	1.9724763264744	0.048555256199785	0.48490851880719	0.48490851880719
1736	Kcnj2	2.1031	8.31194	-1.9826677899402	-1.9652136553587	-1.9695443830333	0.04889061115678	0.48769511140666	0.48769511140666
1737	Dysf	9.97829	20.9876	-1.0726726949613	-1.0552185603798	-1.967501087875	0.049125470624337	0.48975577133083	0.48975577133083
1739	Pxmp4	17.958	8.18733	1.1331617335255	1.150615868107	1.9638020474642	0.049553052569191	0.49345038029942	0.49339804241309
1741	Gusb	49.9127	32.6357	0.61295596388206	0.63041009846357	1.9630125446972	0.049644716407608	0.49379526365913	0.49379526365913
1742	Edil3	16.6601	30.2809	-0.86201102500682	-0.84455689042531	-1.9618247814171	0.049782887474307	0.49488534006462	0.49488534006462
	GeneNames	value1	value2	log2.Fold_change.	log2.Fold_change..normalized	z.score	p.value	q.value.Benjamini.et.al..1995.	q.value.Storey.et.al..2003.	Signature.p.value…0.001.
1	Rn45s	11920.6359	1214.138318	3.2954565057709	3.4764390155395	105.83783126073	0	0	0	1
2	Col1a2	10892.69675	4788.535376	1.1857048071923	1.3666873169609	57.644206184518	0	0	0	1
3	Col1a1	15645.40087	9729.199505	0.68534561056712	0.86632812033578	48.158567354338	0	0	0	1
4	Fn1	2070.699253	6750.367655	-1.7048480471892	-1.5238655374206	-45.98609851569	0	0	0	1
5	Col3a1	2705.883073	1026.303313	1.398642331623	1.5796248413917	31.720083885692	8.21E-221	2.21E-217	2.21E-217	1
6	Sfrp2	849.9700523	49.28468683	4.1082006467138	4.2891831564825	30.114895994395	3.09E-199	6.93E-196	6.93E-196	1
7	Matn4	656.4742405	23.63653348	4.7956480307405	4.9766305405092	27.25578072801	1.42E-163	2.73E-160	2.73E-160	1
8	Lum	709.5238521	59.21705994	3.5827664150244	3.7637489247931	26.445524469949	4.11E-154	6.91E-151	6.91E-151	1
9	Ptn	614.599159	40.73530238	3.9152942702556	4.0962767800243	25.28575891019	4.58E-141	6.85E-138	6.85E-138	1
10	Thbs1	3574.438133	6670.154313	-0.90000365627761	-0.71902114650894	-24.842341853137	3.13E-136	4.21E-133	4.21E-133	1
11	Cxcl12	508.9704423	20.11619871	4.661152261558	4.8421347713267	23.900296961502	3.04E-126	3.72E-123	3.72E-123	1
12	Gas6	767.7490356	134.6528051	2.5113905104634	2.692373020232	23.697473396128	3.83E-124	4.29E-121	4.29E-121	1
13	Col2a1	285.3622124	1254.244989	-2.1359529629909	-1.9549704532222	-23.481901983592	6.24E-122	6.46E-119	6.46E-119	1
14	Lars2	546.1404584	46.77016199	3.5456117057514	3.72659421552	23.11944899763	2.95E-118	2.84E-115	2.84E-115	1
15	Lyz2	541.0825132	49.66186556	3.4456382539675	3.6266207637362	22.786292118961	6.27E-115	5.62E-112	5.62E-112	1
16	Igfbp4	1512.443251	610.5266308	1.3087548802765	1.4897373900451	22.690995607662	5.50E-114	4.62E-111	4.62E-111	1
17	Acta2	455.0974443	1522.670516	-1.7423564074689	-1.5613738977002	-22.130639626134	1.60E-108	1.27E-105	1.27E-105	1
18	Apoe	367.936109	16.21868521	4.5037264930185	4.6847090027872	20.203192568494	9.18E-91	6.86E-88	6.86E-88	1
19	Serpine1	34.22935029	473.3593008	-3.7896298553825	-3.6086473456138	-19.978669556673	8.44E-89	5.98E-86	5.98E-86	1
20	Dcn	401.4596995	38.84940875	3.3692906226789	3.5502731324476	19.468900943818	2.02E-84	1.36E-81	1.36E-81	1
21	Tagln	214.7862324	888.3816254	-2.0482780327411	-1.8672955229724	-19.160283524774	7.94E-82	5.09E-79	5.09E-79	1
22	Gpx3	322.2969753	12.06971922	4.7389266290961	4.9199091388648	19.064507333376	4.98E-81	3.04E-78	3.04E-78	1
23	Sparc	4138.928346	3005.988718	0.46141767796544	0.6424001877341	18.823329916424	4.86E-79	2.84E-76	2.84E-76	1
24	Flna	478.1522644	1367.775786	-1.5162897412942	-1.3353072315255	-18.653898728574	1.17E-77	6.58E-75	6.58E-75	1
25	Hspg2	302.4180742	1041.390462	-1.7838948275951	-1.6029123178265	-18.646098533883	1.36E-77	7.31E-75	7.31E-75	1
26	Lox	570.6067982	1487.592894	-1.3824109211694	-1.2014284114008	-17.917350807611	8.63E-72	4.47E-69	4.47E-69	1
27	Fmod	1078.518601	479.6456129	1.1690102921102	1.3499928018789	17.782796461365	9.61E-71	4.79E-68	4.79E-68	1
28	Penk	215.4919922	2.765977322	6.2837011207407	6.4646836305094	15.671887783535	2.35E-55	1.13E-52	1.13E-52	1
29	Postn	384.0509577	85.99674947	2.1589437127043	2.3399262224729	15.48039371928	4.71E-54	2.18E-51	2.18E-51	1
30	Mir6236	243.2518777	23.88798596	3.3480938136784	3.5290763234471	15.118533080065	1.22E-51	5.48E-49	5.48E-49	1
31	Abi3bp	246.66305	26.02533208	3.2445531394727	3.4255356492413	15.045129423874	3.72E-51	1.61E-48	1.61E-48	1
32	Igfbp5	432.2778774	125.4747894	1.784561480958	1.9655439907267	14.721765450172	4.67E-49	1.96E-46	1.96E-46	1
33	Fth1	794.6855346	371.2695924	1.0979169228668	1.2788994326354	14.635853561357	1.66E-48	6.76E-46	6.76E-46	1
34	Cst3	335.5887848	72.92122031	2.2022838928103	2.383266402579	14.627923258154	1.86E-48	7.37E-46	7.37E-46	1
35	Col5a1	849.0290392	1737.410937	-1.0330532204358	-0.85207071066714	-14.596693680318	2.95E-48	1.13E-45	1.13E-45	1
36	Slc7a5	11.6450367	229.198939	-4.2988132742304	-4.1178307644618	-14.522108074699	8.78E-48	3.28E-45	3.28E-45	1
37	Gpnmb	233.9593736	28.16267819	3.0544015897658	3.2353840995345	14.302847591146	2.10E-46	7.63E-44	7.63E-44	1
38	Myh9	330.2955863	879.2036098	-1.4124396184677	-1.2314571086991	-14.037018912456	9.25E-45	3.27E-42	3.27E-42	1
39	Islr	229.2543083	31.55728672	2.8609037725776	3.0418862823462	13.765531838269	4.11E-43	1.42E-40	1.42E-40	1
40	Col14a1	181.7331485	13.32698164	3.7693996202118	3.9503821299805	13.597269912247	4.16E-42	1.40E-39	1.40E-39	1
41	Sfrp1	158.6783283	7.920753241	4.3243236604371	4.5053061702058	13.161549192899	1.46E-39	4.79E-37	4.79E-37	1
42	Ogn	334.883025	95.55194386	1.8093001205706	1.9902826303393	13.063455644547	5.33E-39	1.71E-36	1.71E-36	1
43	Egfl6	143.5044926	4.777597193	4.9086668699266	5.0896493796952	12.777972134381	2.18E-37	6.81E-35	6.81E-35	1
44	Cemip	238.5468123	663.2059261	-1.4751844904202	-1.2942019806516	-12.671209908707	8.54E-37	2.61E-34	2.61E-34	1
45	Pcolce	444.9815538	174.63375	1.349413128568	1.5303956383367	12.541515793186	4.42E-36	1.32E-33	1.32E-33	1
46	Kctd12	312.6515913	90.52289418	1.7882012441255	1.9691837538942	12.534120225103	4.86E-36	1.42E-33	1.42E-33	1
47	Fbln2	90.80776091	373.2812123	-2.0393753896398	-1.8583928798711	-12.374881698823	3.57E-35	1.02E-32	1.02E-32	1
48	Ibsp	182.4389083	0	9.5029119217203	9.683894431489	12.36475129585	4.05E-35	1.14E-32	1.14E-32	1
49	Cpxm2	174.0874173	20.74482992	3.0689881973739	3.2499707071426	12.361675959138	4.21E-35	1.16E-32	1.16E-32	1
50	Flnb	112.4510614	412.0048948	-1.8733641989137	-1.6923816891451	-12.185684594531	3.71E-34	9.97E-32	9.97E-32	1
51	Cpxm1	134.3296152	8.297931967	4.0168817668419	4.1978642766106	11.900742588545	1.17E-32	3.09E-30	3.09E-30	1
52	Clec11a	236.9000395	57.5826188	2.040573131293	2.2215556410617	11.781181698331	4.88E-32	1.26E-29	1.26E-29	1
53	Itm2b	379.463519	146.8482506	1.3696351150031	1.5506176247718	11.692674106081	1.39E-31	3.53E-29	3.53E-29	1
54	Ctsb	512.9697478	243.2802781	1.0762543752734	1.2572368850421	11.599699228289	4.14E-31	1.03E-28	1.03E-28	1
55	Psap	669.5307968	366.7434477	0.86837922686705	1.0493617366357	11.469280703366	1.88E-30	4.60E-28	4.60E-28	1
56	Chrdl1	117.7442599	5.90913337	4.3165663580023	4.497548867771	11.333060884803	9.00E-30	2.16E-27	2.16E-27	1
57	Atf5	52.93198499	261.7620357	-2.3060442108771	-2.1250617011084	-11.313471948022	1.13E-29	2.66E-27	2.66E-27	1
58	1500015O10Rik	124.2137248	8.800836934	3.8190400540813	4.0000225638499	11.284851996225	1.56E-29	3.62E-27	3.62E-27	1
59	Rcn3	373.1116808	150.3685853	1.311104332941	1.4920868427097	11.270497089095	1.84E-29	4.18E-27	4.18E-27	1
60	Nov	257.7199536	76.81873381	1.7462741506457	1.9272566604144	11.21830625756	3.32E-29	7.43E-27	7.43E-27	1
61	Tubb5	229.2543083	592.5477782	-1.3699826396504	-1.1890001298817	-11.205534842003	3.83E-29	8.44E-27	8.44E-27	1
62	Eef2	600.483963	1170.511312	-0.96294125514002	-0.78195874537135	-11.122864527267	9.71E-29	2.11E-26	2.11E-26	1
63	Adam23	195.1425847	42.87264849	2.1863991936927	2.3673817034614	11.109678985296	1.13E-28	2.40E-26	2.40E-26	1
64	Ccnd2	232.3126008	593.4278619	-1.3530052549936	-1.1720227452249	-11.086349259053	1.46E-28	3.07E-26	3.07E-26	1
65	Ctgf	79.63323075	312.9326161	-1.9744095399265	-1.7934270301579	-11.057723423849	2.01E-28	4.16E-26	4.16E-26	1
66	Itgb1	307.5936461	716.136674	-1.2192092485903	-1.0382267388216	-11.043208043572	2.36E-28	4.82E-26	4.82E-26	1
67	H2-K1	147.1509183	20.61910367	2.8352430214914	3.0162255312601	10.983661848231	4.58E-28	9.19E-26	9.19E-26	1
68	Thbs2	979.5946022	641.9581912	0.60970548229776	0.79068799206642	10.937693614705	7.61E-28	1.51E-25	1.51E-25	1
69	Ptx3	148.6800645	441.9277404	-1.5715992746712	-1.3906167649025	-10.927525169623	8.51E-28	1.66E-25	1.66E-25	1
70	Tnmd	214.6686058	55.69672517	1.9464468114924	2.1274293212611	10.916089713232	9.66E-28	1.86E-25	1.86E-25	1
71	Actb	436.6300628	911.8924327	-1.0624521873661	-0.88146967759741	-10.874081103021	1.53E-27	2.90E-25	2.90E-25	1
72	Piezo1	97.04197248	338.4550433	-1.8022834343912	-1.6213009246225	-10.71125975695	9.01E-27	1.68E-24	1.68E-24	1
73	Flnc	72.69325938	288.0388202	-1.9863697640011	-1.8053872542324	-10.657205681083	1.61E-26	2.97E-24	2.97E-24	1
74	Pgm5	110.4514087	8.046479483	3.7789102992345	3.9598928090031	10.608049229305	2.73E-26	4.97E-24	4.94E-24	1
75	Col6a3	390.5204226	829.2902917	-1.0864792058397	-0.90549669607108	-10.607248735353	2.76E-26	4.94E-24	4.94E-24	1
76	Pabpc1	194.5544515	511.7058046	-1.3951406085867	-1.214158098818	-10.586310747834	3.45E-26	6.10E-24	6.10E-24	1
77	Lgr5	116.8032469	10.81245681	3.4333141037774	3.614296613546	10.571347550607	4.05E-26	7.07E-24	7.07E-24	1
78	Gdf10	119.1557795	12.44689795	3.2589907895258	3.4399732992945	10.474008167229	1.14E-25	1.96E-23	1.96E-23	1
79	Comp	108.9222624	8.549384451	3.6713344926548	3.8523170024235	10.441026076437	1.61E-25	2.74E-23	2.74E-23	1
80	Hspa9	53.99062469	239.0055859	-2.1462635219606	-1.9652810121919	-10.278306979306	8.83E-25	1.48E-22	1.48E-22	1
81	Mest	250.191849	85.61957075	1.5470222809324	1.7280047907011	10.258746925083	1.08E-24	1.79E-22	1.79E-22	1
82	Cyr61	113.7449544	357.3139795	-1.6513898084386	-1.4704072986699	-10.246108413723	1.23E-24	2.02E-22	2.02E-22	1
83	Fkbp9	428.3961985	212.6030751	1.0107832137422	1.1917657235108	10.162235668255	2.92E-24	4.74E-22	4.74E-22	1
84	Hspa5	246.1925435	576.4548192	-1.2274204710072	-1.0464379612385	-9.9705610673104	2.05E-23	3.28E-21	3.28E-21	1
85	Aspn	205.9642349	63.8689309	1.6892076326918	1.8701901424605	9.8281597661968	8.52E-23	1.35E-20	1.35E-20	1
86	Marcks	452.8625382	238.8798596	0.92278797871865	1.1037704884873	9.8260388065172	8.70E-23	1.36E-20	1.36E-20	1
87	Timp3	169.6176052	442.9335503	-1.3848043592706	-1.2038218495019	-9.7822814869979	1.34E-22	2.07E-20	2.07E-20	1
88	Stab1	100.8060247	9.932373112	3.343299596537	3.5242821063057	9.7266794714472	2.32E-22	3.55E-20	3.55E-20	1
89	Cald1	362.9957904	745.6823408	-1.0386083584891	-0.85762584872047	-9.6052010864177	7.60E-22	1.15E-19	1.15E-19	1
90	Aars	45.40388046	204.8080481	-2.1733848999539	-1.9924023901852	-9.600427933017	7.96E-22	1.19E-19	1.19E-19	1
91	Gas1	169.4999786	45.63862582	1.8929578334014	2.0739403431701	9.5437604628014	1.38E-21	2.04E-19	2.04E-19	1
92	Mgp	267.7182174	109.5075567	1.289684885113	1.4706673948816	9.4438670499969	3.59E-21	5.25E-19	5.25E-19	1
93	Ahnak	216.7858852	510.0713635	-1.2344282802816	-1.053445770513	-9.4296022320823	4.12E-21	5.95E-19	5.95E-19	1
94	Psat1	13.64468946	123.3374433	-3.1761993799192	-2.9952168701506	-9.4125744258463	4.84E-21	6.93E-19	6.93E-19	1
95	Col16a1	250.4271023	98.82082615	1.341503683399	1.5224861931677	9.370896902022	7.19E-21	1.02E-18	1.02E-18	1
96	Itgbl1	96.57146594	11.06390929	3.1257357442087	3.3067182539774	9.2756922004581	1.76E-20	2.47E-18	2.47E-18	1
97	Htra1	172.911151	51.04485422	1.7601934741272	1.9411759838959	9.2323123018915	2.65E-20	3.67E-18	3.67E-18	1
98	Ctsd	869.7313267	610.7780833	0.50992150475278	0.69090401452145	9.1616361061523	5.11E-20	7.01E-18	7.01E-18	1
99	Asns	10.82165026	110.6390929	-3.3538688068898	-3.1728862971212	-9.1572722672844	5.32E-20	7.23E-18	7.23E-18	1
100	H19	1048.170929	772.7134828	0.43986852517177	0.62085103494044	9.1507354277424	5.65E-20	7.61E-18	7.61E-18	1
101	B2m	266.3066978	114.6623326	1.2156971802987	1.3966796900674	9.0605559889871	1.30E-19	1.73E-17	1.73E-17	1
102	Marco	77.28069808	0	7.678716009912	7.8596985196807	8.9598655200358	3.25E-19	4.29E-17	4.29E-17	1
103	Bst2	87.74946845	9.80664687	3.1615585526859	3.3425410624545	8.8823009958586	6.55E-19	8.55E-17	8.55E-17	1
104	Sepp1	73.51664582	4.400418467	4.0623583140106	4.2433408237793	8.8293253093079	1.05E-18	1.36E-16	1.36E-16	1
105	Il6st	102.4527976	294.9537635	-1.52552943808	-1.3445469283114	-8.6996563434939	3.33E-18	4.26E-16	4.26E-16	1
106	Emilin1	208.5520208	80.71624731	1.369476284734	1.5504587945027	8.6662354358793	4.47E-18	5.67E-16	5.67E-16	1
107	Cdh11	536.3774479	336.3176971	0.6734238843639	0.85440639413256	8.6446737761042	5.40E-18	6.78E-16	6.78E-16	1
108	Actn4	127.036764	335.8147922	-1.4024197121182	-1.2214372023495	-8.6150461994211	6.99E-18	8.71E-16	8.71E-16	1
109	Olfml3	107.5107428	22.63072355	2.2481262091555	2.4291087189242	8.370583415064	5.73E-17	7.07E-15	7.07E-15	1
110	Mpeg1	79.28035085	9.429468144	3.0717150419849	3.2526975517536	8.3447433105457	7.14E-17	8.73E-15	8.73E-15	1
111	Ctss	67.63531415	4.777597193	3.8234195836228	4.0044020933914	8.3297721183723	8.10E-17	9.81E-15	9.81E-15	1
112	Mrc1	64.45939505	3.771787258	4.0950704384282	4.2760529481969	8.2841789523037	1.19E-16	1.43E-14	1.43E-14	1
113	Fat1	298.654022	596.1938392	-0.99730631643049	-0.81632380666182	-8.2324402844394	1.83E-16	2.18E-14	2.18E-14	1
114	Myo1c	85.63218905	252.58402	-1.5605382571145	-1.3795557473458	-8.2099080724298	2.21E-16	2.61E-14	2.61E-14	1
115	Actn1	116.3327403	305.7662204	-1.3941718521476	-1.2131893423789	-8.1765158836253	2.92E-16	3.42E-14	3.42E-14	1
116	Unc5b	40.93406839	165.2042819	-2.0128771133733	-1.8318946036047	-8.1511864742872	3.60E-16	4.18E-14	4.18E-14	1
117	Epyc	57.51942369	1.634441145	5.1371798881272	5.3181623978959	8.1245916987971	4.49E-16	5.16E-14	5.16E-14	1
118	Lpl	83.39728301	13.32698164	2.6456503142559	2.8266328240246	8.0075663970316	1.17E-15	1.33E-13	1.33E-13	1
119	Ipo5	31.05343119	141.1905697	-2.1848191421481	-2.0038366323795	-8.0006252353896	1.24E-15	1.40E-13	1.40E-13	1
120	Lgals3bp	137.8584142	43.5012797	1.6640575778333	1.845040087602	7.9667306810006	1.63E-15	1.83E-13	1.83E-13	1
121	Fbn1	127.977777	319.7218332	-1.3209239545775	-1.1399414448089	-7.9567458191674	1.77E-15	1.96E-13	1.96E-13	1
122	Alpl	69.16446038	7.417848273	3.220958246714	3.4019407564827	7.943645776134	1.96E-15	2.16E-13	2.16E-13	1
123	Lgmn	103.0409308	23.76225972	2.1164735871572	2.2974560969258	7.9294471062822	2.20E-15	2.41E-13	2.41E-13	1
124	Lect1	64.92990158	5.783407128	3.4888914519588	3.6698739617275	7.9260885379553	2.26E-15	2.45E-13	2.45E-13	1
125	Mylk	73.51664582	9.429468144	2.9628226403941	3.1438051501628	7.9146051884395	2.48E-15	2.67E-13	2.67E-13	1
126	Plec	156.4434223	361.9658505	-1.2102125919292	-1.0292300821605	-7.7923676551605	6.58E-15	7.02E-13	7.02E-13	1
127	Cdkn1c	76.22205838	11.44108801	2.7359843145048	2.9169668242734	7.7772507438069	7.41E-15	7.85E-13	7.85E-13	1
128	Tpm4	200.9062897	431.1152835	-1.1015509778061	-0.92056846803746	-7.7516163798903	9.07E-15	9.53E-13	9.53E-13	1
129	Igf2r	77.63357798	227.3130454	-1.5499277969937	-1.368945287225	-7.7425340262842	9.75E-15	1.02E-12	1.02E-12	1
130	Cp	62.57736892	5.783407128	3.4356494308188	3.6166319405875	7.7393587633627	9.99E-15	1.03E-12	1.03E-12	1
131	Ltbp1	45.75676036	166.3358181	-1.862042050246	-1.6810595404774	-7.7044313102305	1.31E-14	1.35E-12	1.35E-12	1
132	Col8a1	680.1171938	490.4580697	0.47165356185987	0.65263607162854	7.7019662115904	1.34E-14	1.37E-12	1.37E-12	1
133	Nars	54.81401112	183.9374919	-1.7465989580058	-1.5656164482371	-7.6980744801467	1.38E-14	1.40E-12	1.40E-12	1
134	Inhbb	6.469464832	74.30420898	-3.5217256554505	-3.3407431456818	-7.6747797271919	1.66E-14	1.66E-12	1.66E-12	1
135	Tenm3	115.9798604	292.06206	-1.332400651756	-1.1514181419873	-7.6658656527287	1.78E-14	1.77E-12	1.77E-12	1
136	Eef1a1	443.3347809	782.5201297	-0.81973131413494	-0.63874880436627	-7.6125283925032	2.69E-14	2.66E-12	2.66E-12	1
137	Fscn1	120.5672991	296.8396572	-1.299845181162	-1.1188626713933	-7.552345991585	4.27E-14	4.20E-12	4.20E-12	1
138	Serping1	50.81470559	2.011619871	4.658816453281	4.8397989630496	7.5501474956402	4.35E-14	4.24E-12	4.24E-12	1
139	Tead1	51.87334529	175.2623812	-1.7564510486865	-1.5754685389179	-7.5486757876731	4.40E-14	4.25E-12	4.25E-12	1
140	Serpinf1	294.6547164	565.3909099	-0.94022332943753	-0.75924081966886	-7.5303086914814	5.06E-14	4.86E-12	4.86E-12	1
141	Tgfb3	45.75676036	162.8154833	-1.8311810863162	-1.6501985765476	-7.5226445873782	5.37E-14	5.12E-12	5.12E-12	1
142	Adamts5	74.10477898	215.3690524	-1.5391724664239	-1.3581899566552	-7.4910373730349	6.83E-14	6.47E-12	6.47E-12	1
143	Aldh1l2	6.116584932	70.40669548	-3.5249143476145	-3.3439318378459	-7.473770279246	7.79E-14	7.33E-12	7.33E-12	1
144	Plxna1	110.9219152	278.4836259	-1.3280480718431	-1.1470655620745	-7.462777736819	8.47E-14	7.91E-12	7.91E-12	1
145	Mmp13	136.4468946	48.15315066	1.5026374588483	1.6836199686169	7.4376227093923	1.03E-13	9.51E-12	9.51E-12	1
146	Igf1	134.5648685	47.27306696	1.5092114364042	1.6901939461728	7.4065336761006	1.30E-13	1.19E-11	1.19E-11	1
147	Tll1	69.39971365	10.56100432	2.716182672901	2.8971651826697	7.3959660054716	1.40E-13	1.28E-11	1.28E-11	1
148	Adamts2	131.9770826	46.01580454	1.5200860740122	1.7010685837809	7.3682448132923	1.73E-13	1.57E-11	1.57E-11	1
149	Canx	126.3310042	301.1143494	-1.2531027110436	-1.0721202012749	-7.348100416948	2.01E-13	1.81E-11	1.81E-11	1
150	Col4a1	355.1148059	646.3586097	-0.86404930415225	-0.68306679438358	-7.3407457904659	2.12E-13	1.90E-11	1.90E-11	1
151	Zyx	89.04336141	238.1255022	-1.4191421742798	-1.2381596645112	-7.3318880779553	2.27E-13	2.02E-11	2.02E-11	1
152	Gfra2	56.10790409	5.531954645	3.3423427885777	3.5233252983464	7.2556753205722	4.00E-13	3.54E-11	3.54E-11	1
153	Ltbp4	12.11554323	83.48222464	-2.7846099530469	-2.6036274432782	-7.2039756838125	5.85E-13	5.14E-11	5.14E-11	1
154	Msn	93.16029358	241.7715632	-1.3758574758952	-1.1948749661266	-7.1832644577	6.81E-13	5.94E-11	5.94E-11	1
156	Amotl2	81.16237698	220.6495546	-1.4428738124785	-1.2618913027098	-7.1633408108337	7.87E-13	6.79E-11	6.79E-11	1
157	Ctsz	143.7397459	56.19963014	1.3548264998579	1.5358090096265	7.1443682928155	9.04E-13	7.74E-11	7.74E-11	1
158	Col26a1	44.22761412	0	5.8735553012058	6.0545378109744	7.1390426395458	9.40E-13	8.00E-11	8.00E-11	1
159	Msx2	15.29146233	90.01998922	-2.5575190130327	-2.376536503264	-7.102386334091	1.23E-12	1.04E-10	1.04E-10	1
160	Cfh	45.28625382	2.011619871	4.4926435865589	4.6736260963276	7.0839573141464	1.40E-12	1.18E-10	1.18E-10	1
161	Hsp90b1	277.9517345	525.409965	-0.9186091781372	-0.73762666836853	-7.0786971717008	1.46E-12	1.22E-10	1.22E-10	1
162	Gars	41.63982819	146.3453456	-1.81334084162	-1.6323583318514	-7.0766609701125	1.48E-12	1.23E-10	1.23E-10	1
163	Tapbp	116.2151137	39.47803996	1.5576754339867	1.7386579437554	7.0210575913837	2.20E-12	1.82E-10	1.82E-10	1
164	Pappa	35.28798999	132.515459	-1.9089115101256	-1.727929000357	-7.0110577318135	2.37E-12	1.94E-10	1.94E-10	1
165	Mdk	48.10929302	3.520334774	3.7725310619882	3.9535135717568	6.997336235552	2.61E-12	2.13E-10	2.13E-10	1
166	Akap12	59.28382319	176.5196437	-1.574118345808	-1.3931358360393	-6.914063165301	4.71E-12	3.82E-10	3.82E-10	1
167	Sdpr	13.52706283	82.09923597	-2.6015201792893	-2.4205376695206	-6.8557933372062	7.09E-12	5.71E-10	5.71E-10	1
168	Isg15	42.81609452	2.137346113	4.3242607498583	4.505243259627	6.8364812912204	8.12E-12	6.50E-10	6.50E-10	1
169	Cd44	49.99131915	157.4092549	-1.6547708649344	-1.4737883551658	-6.8110579123346	9.69E-12	7.71E-10	7.71E-10	1
170	Slc3a2	35.75849652	129.8752079	-1.8607680743199	-1.6797855645512	-6.804000597854	1.02E-11	8.05E-10	8.05E-10	1
171	App	421.9267337	719.1541038	-0.76930845036928	-0.58832594060062	-6.7802937482275	1.20E-11	9.43E-10	9.43E-10	1
172	Thy1	132.6828424	52.93074785	1.3258038808888	1.5067863906575	6.7682634986213	1.30E-11	1.02E-9	1.02E-9	1
173	Lbp	40.11068196	1.382988661	4.8581252618745	5.0391077716431	6.7470785551268	1.51E-11	1.17E-9	1.17E-9	1
174	Ccng1	113.9802077	265.9110017	-1.2221601412027	-1.041177631434	-6.7417576304912	1.56E-11	1.21E-9	1.21E-9	1
175	Trf	39.87542869	1.382988661	4.8496387958646	5.0306213056333	6.7258172145356	1.75E-11	1.34E-9	1.34E-9	1
176	Cyb5r1	12.23316986	76.94446006	-2.6530191738286	-2.4720366640599	-6.7180371168578	1.84E-11	1.41E-9	1.41E-9	1
177	Igf1r	23.40770003	102.7183396	-2.1336386955221	-1.9526561857534	-6.7088559258947	1.96E-11	1.49E-9	1.49E-9	1
178	Lgals3	63.28312872	11.6925405	2.4362325025692	2.6172150123378	6.6972208719687	2.12E-11	1.60E-9	1.60E-9	1
179	Apod	57.63705032	9.052289418	2.670641888867	2.8516243986356	6.6866776350223	2.28E-11	1.72E-9	1.71E-9	1
180	Dync1h1	152.4441168	325.3795141	-1.0938429475546	-0.91286043778596	-6.6860538035974	2.29E-11	1.71E-9	1.71E-9	1
181	Ybx3	41.05169502	137.6702349	-1.7457029771201	-1.5647204673514	-6.6568458112067	2.80E-11	2.08E-9	2.08E-9	1
182	11-Sep	68.10582068	186.2005643	-1.4510074362488	-1.2700249264801	-6.6132996338969	3.76E-11	2.78E-9	2.78E-9	1
184	Steap4	37.99340256	0	6.6543568044038	6.8353393141725	6.524749798035	6.81E-11	4.98E-9	4.98E-9	1
185	Prelp	171.617258	83.9851296	1.0309888268098	1.2119713365785	6.5163281776975	7.20E-11	5.24E-9	5.24E-9	1
186	Grn	198.0832505	104.981412	0.91597298710839	1.0969554968771	6.4642090515122	1.02E-10	7.36E-9	7.36E-9	1
187	Grem2	20.81991409	93.16314526	-2.1617952312715	-1.9808127215028	-6.4497333194661	1.12E-10	8.06E-9	8.06E-9	1
188	Sema3e	1.529146233	42.62119601	-4.8007727936777	-4.6197902839091	-6.439969442298	1.19E-10	8.55E-9	8.55E-9	1
189	Cpz	47.52115986	5.783407128	3.0385784781744	3.2195609879431	6.4315118822631	1.26E-10	8.99E-9	8.99E-9	1
190	Mthfd2	7.410477898	60.47432236	-3.0286842089733	-2.8477016992046	-6.428367151272	1.29E-10	9.13E-9	9.13E-9	1
191	Mfap2	49.16793272	6.53776458	2.9108483651155	3.0918308748841	6.4230778245528	1.34E-10	9.40E-9	9.40E-9	1
192	Htra3	41.52220156	3.394608532	3.6125658224103	3.793548332179	6.4129614564986	1.43E-10	1.00E-8	1.00E-8	1
193	Tsc22d2	27.87751209	106.3644007	-1.9318416536209	-1.7508591438523	-6.3392591546764	2.31E-10	1.61E-8	1.61E-8	1
194	Clu	62.69499555	13.82988661	2.1805609605784	2.361543470347	6.2873316790045	3.23E-10	2.24E-8	2.24E-8	1
195	Igfbp3	51.40283875	8.423658209	2.6093292301156	2.7903117398843	6.2449118286217	4.24E-10	2.92E-8	2.92E-8	1
196	Hexa	128.2130303	55.82245141	1.1996255046054	1.3806080143741	6.2309042038234	4.64E-10	3.18E-8	3.18E-8	1
197	Timp1	94.45418654	222.0325432	-1.2330844987366	-1.052101988968	-6.2130388105228	5.20E-10	3.55E-8	3.55E-8	1
198	Eif3c	50.81470559	147.8540605	-1.5408558913749	-1.3598733816062	-6.2122794592996	5.22E-10	3.55E-8	3.55E-8	1
199	Iars	22.46668696	93.03741902	-2.050023681294	-1.8690411715254	-6.2006435260771	5.62E-10	3.80E-8	3.80E-8	1
200	Nrep	37.05238949	2.64025108	3.8108195469962	3.9918020567649	6.1592593332458	7.31E-10	4.91E-8	4.91E-8	1
201	Trib3	2.940665833	43.62700595	-3.8910067114892	-3.7100242017205	-6.1259314077797	9.02E-10	6.03E-8	6.03E-8	1
202	Tln1	155.8552891	314.8185098	-1.0143132517577	-0.83333074198904	-6.0869857951272	1.15E-9	7.66E-8	7.66E-8	1
203	Rbpjl	32.58257743	1.131536177	4.8477461164185	5.0287286261872	6.0794344284636	1.21E-9	7.99E-8	7.99E-8	1
204	Hsph1	33.52359049	113.4050702	-1.7582365628808	-1.5772540531121	-6.0768297364664	1.23E-9	8.08E-8	8.08E-8	1
205	Arhgef2	28.93615179	104.3527808	-1.8505240698799	-1.6695415601112	-6.0723737783901	1.26E-9	8.27E-8	8.27E-8	1
206	Tmem119	72.10512622	20.61910367	1.8061202107496	1.9871027205182	6.0540096301439	1.41E-9	9.22E-8	9.22E-8	1
207	Rplp0	193.4958118	369.7608775	-0.9342902489626	-0.75330773919393	-6.047022371208	1.48E-9	9.59E-8	9.59E-8	1
208	Laptm5	41.63982819	5.029049677	3.049606406394	3.2305889161627	6.0294498392554	1.65E-9	1.06E-7	1.06E-7	1
209	Pcsk5	45.05100056	6.53776458	2.7846898151373	2.9656723249059	6.0277567135698	1.66E-9	1.07E-7	1.07E-7	1
210	Eprs	55.99027745	153.6374676	-1.4562818550916	-1.275299345323	-6.0265059235042	1.68E-9	1.07E-7	1.07E-7	1
211	Actg2	25.64260606	96.43202755	-1.9109694914594	-1.7299869816907	-5.9856342417468	2.16E-9	1.37E-7	1.37E-7	1
212	Mxra8	186.4382138	103.4726971	0.84944745595164	1.0304299657203	5.9592465159108	2.53E-9	1.61E-7	1.61E-7	1
213	Hyou1	42.81609452	128.6179455	-1.5868668385714	-1.4058843288027	-5.9424430347865	2.81E-9	1.77E-7	1.77E-7	1
214	Rspo2	39.87542869	4.651870951	3.0996170487602	3.2805995585289	5.9399551766204	2.85E-9	1.79E-7	1.79E-7	1
215	Axl	51.63809202	144.3337257	-1.4829008456691	-1.3019183359005	-5.9356030798117	2.93E-9	1.83E-7	1.83E-7	1
216	H2-D1	59.04856992	14.20706534	2.0552935425033	2.236276052272	5.9048799971527	3.53E-9	2.20E-7	2.20E-7	1
217	Robo2	39.75780206	4.777597193	3.0568808741868	3.2378633839555	5.8974368118593	3.69E-9	2.29E-7	2.29E-7	1
218	Col11a1	484.5041026	366.1148165	0.40421272185988	0.58519523162855	5.8959811490671	3.72E-9	2.30E-7	2.30E-7	1
220	Clec4n	30.46529803	1.131536177	4.7508122380456	4.9317947478143	5.8629316843625	4.55E-9	2.78E-7	2.78E-7	1
221	Ugcg	15.99722213	74.30420898	-2.2156225277281	-2.0346400179594	-5.8615582692688	4.59E-9	2.79E-7	2.79E-7	1
223	Fcgrt	74.57528552	23.63653348	1.6576791298646	1.8386616396333	5.8453787048696	5.05E-9	3.05E-7	3.05E-7	1
224	Sptbn1	162.2071273	317.9616658	-0.97101562906885	-0.79003311930018	-5.8431865007215	5.12E-9	3.07E-7	3.07E-7	1
225	Smoc2	67.87056742	19.73901998	1.7817357111779	1.9627182209465	5.8260228892885	5.68E-9	3.39E-7	3.39E-7	1
226	Gnb2l1	203.8469555	377.9330832	-0.89064440358184	-0.70966189381317	-5.8030886990674	6.51E-9	3.87E-7	3.87E-7	1
227	Actg1	110.4514087	237.999776	-1.1075483967232	-0.9265658869545	-5.7897780329306	7.05E-9	4.18E-7	4.18E-7	1
228	Scara5	42.34558799	6.412038338	2.7233567056017	2.9043392153704	5.7842500647855	7.28E-9	4.30E-7	4.30E-7	1
229	Fam46a	46.34489352	8.675110693	2.4174563137789	2.5984388235475	5.708642275002	1.14E-8	6.69E-7	6.69E-7	1
230	Nqo1	4.705065332	44.3813634	-3.2376673272633	-3.0566848174946	-5.7008484293249	1.19E-8	6.97E-7	6.97E-7	1
231	Lyz1	28.34801863	0	6.2318557860234	6.412838295792	5.6892805396429	1.28E-8	7.43E-7	7.43E-7	1
232	Fst	73.39901918	24.26516469	1.5968741328366	1.7778566426052	5.6667156901779	1.46E-8	8.44E-7	8.44E-7	1
233	Pkm	165.9711796	318.2131183	-0.93906056820314	-0.75807805843447	-5.6402292284841	1.70E-8	9.80E-7	9.80E-7	1
234	Alcam	25.99548596	91.65443036	-1.8179434937083	-1.6369609839397	-5.6114103207436	2.01E-8	1.15E-6	1.15E-6	1
235	Crim1	14.58570253	67.89217064	-2.2186903354595	-2.0377078256908	-5.6083823840218	2.04E-8	1.17E-6	1.17E-6	1
236	Crabp1	39.16966889	5.783407128	2.759745362328	2.9407278720966	5.5973946285422	2.18E-8	1.24E-6	1.24E-6	1
237	Cdkn1a	151.9736102	296.3367522	-0.96341673756042	-0.78243422779176	-5.5939594704768	2.22E-8	1.26E-6	1.26E-6	1
238	Lars	21.76092716	82.72786718	-1.9266333620001	-1.7456508522315	-5.5789973663477	2.42E-8	1.37E-6	1.37E-6	1
239	Pam	154.3261429	83.60795088	0.88427042546491	1.0652529352336	5.5710856043628	2.53E-8	1.42E-6	1.42E-6	1
240	Pla2g7	30.23004476	2.137346113	3.8220906589846	4.0030731687533	5.5681996463687	2.57E-8	1.44E-6	1.44E-6	1
241	Phospho1	42.11033472	7.292122031	2.5297637333533	2.710746243122	5.5673546736813	2.59E-8	1.44E-6	1.44E-6	1
242	Dmpk	47.63878649	10.05809935	2.2437789547004	2.424761464469	5.5659658917464	2.61E-8	1.45E-6	1.45E-6	1
244	Slc1a3	38.11102919	5.531954645	2.7843473353354	2.965329845104	5.543737250257	2.96E-8	1.63E-6	1.63E-6	1
245	Myadm	97.98298554	212.9802538	-1.1201165226726	-0.93913401290388	-5.5390666358442	3.04E-8	1.67E-6	1.67E-6	1
246	Pdgfrl	43.63948096	8.297931967	2.3948102085955	2.5757927183641	5.5128182654538	3.53E-8	1.93E-6	1.93E-6	1
247	Cav1	24.11345983	86.49965444	-1.8428557037779	-1.6618731940092	-5.5104244046152	3.58E-8	1.95E-6	1.95E-6	1
248	Pck2	20.70228746	79.58471114	-1.9427011197375	-1.7617186099689	-5.5069830580557	3.65E-8	1.98E-6	1.98E-6	1
249	Oasl2	28.70089853	1.760167387	4.0273113668416	4.2082938766102	5.504408361594	3.70E-8	2.00E-6	2.00E-6	1
250	Col9a2	38.46390909	5.90913337	2.7024869251062	2.8834694348748	5.4929714863451	3.95E-8	2.13E-6	2.13E-6	1
251	Ptk7	60.93059605	152.1287527	-1.3200540930478	-1.1390715832791	-5.4842359898517	4.15E-8	2.23E-6	2.23E-6	1
252	C1qa	30.70055129	2.64025108	3.5395175250983	3.7205000348669	5.4769992914878	4.33E-8	2.31E-6	2.31E-6	1
253	Mmp14	308.0641526	215.8719574	0.51305497132624	0.69403748109491	5.4702439095717	4.49E-8	2.39E-6	2.39E-6	1
254	Cited2	26.34836586	90.2714417	-1.7765561605513	-1.5955736507826	-5.4671839982822	4.57E-8	2.42E-6	2.42E-6	1
255	Phgdh	6.351838198	46.26725703	-2.8647455028529	-2.6837629930842	-5.4517579204234	4.99E-8	2.63E-6	2.63E-6	1
256	C1qtnf6	99.74738504	43.87845843	1.1847661795727	1.3657486893414	5.4505680669595	5.02E-8	2.64E-6	2.64E-6	1
257	Lpp	61.75398248	152.5059314	-1.3042612709689	-1.1232787612002	-5.4297450170301	5.64E-8	2.95E-6	2.95E-6	1
258	Ifit1	31.17105783	3.017429806	3.3688150002156	3.5497975099842	5.4236887390913	5.84E-8	3.04E-6	3.04E-6	1
259	C1qc	32.34732416	3.520334774	3.1998618375609	3.3808443473296	5.4184544145569	6.01E-8	3.12E-6	3.12E-6	1
260	C3	26.34836586	1.131536177	4.5413588722095	4.7223413819781	5.4138223510654	6.17E-8	3.19E-6	3.19E-6	1
261	Shmt2	11.2921568	57.95979753	-2.3597314882275	-2.1787489784588	-5.4067717771004	6.42E-8	3.31E-6	3.31E-6	1
262	Ctsh	48.10929302	11.18963553	2.1041525532912	2.2851350630599	5.400405492677	6.65E-8	3.41E-6	3.41E-6	1
263	Crispld2	7.410477898	48.40460314	-2.7075057608933	-2.5265232511247	-5.3945703456691	6.87E-8	3.51E-6	3.51E-6	1
264	Anxa3	19.99652766	75.93865012	-1.9250848520722	-1.7441023423036	-5.3418343998835	9.20E-8	4.69E-6	4.69E-6	1
265	Amot	29.28903169	93.91750271	-1.6810335495464	-1.5000510397777	-5.3301848083252	9.81E-8	4.98E-6	4.98E-6	1
266	Slc7a1	13.29180956	61.4801323	-2.2095827416847	-2.0286002319161	-5.321488893498	1.03E-7	5.20E-6	5.20E-6	1
267	Tpm2	85.16168251	188.2121842	-1.1440836681191	-0.96310115835038	-5.3176427116999	1.05E-7	5.29E-6	5.29E-6	1
268	Ppic	181.6155218	109.3818305	0.73151439721421	0.91249690698287	5.3160620702503	1.06E-7	5.32E-6	5.32E-6	1
269	Mmp23	68.10582068	23.63653348	1.5267596375487	1.7077421473174	5.3073677683865	1.11E-7	5.56E-6	5.56E-6	1
270	Sorbs2	62.81262218	20.61910367	1.6070728785538	1.7880553883224	5.2628644983598	1.42E-7	7.06E-6	7.06E-6	1
271	Tnrc18	92.92504031	199.1503672	-1.0997188257659	-0.91873631599726	-5.2583572137691	1.45E-7	7.21E-6	7.21E-6	1
272	Abi3	41.87508146	8.675110693	2.2711379254743	2.4521204352429	5.2523044617716	1.50E-7	7.43E-6	7.43E-6	1
273	Il11ra1	47.40353322	11.6925405	2.0194061684387	2.2003886782073	5.238208753371	1.62E-7	7.99E-6	7.99E-6	1
274	Plxnd1	44.81574729	10.30955184	2.1200241337973	2.3010066435659	5.2340464850803	1.66E-7	8.14E-6	8.14E-6	1
275	Eif5a	104.9229569	216.8777673	-1.0475517954089	-0.86656928564023	-5.2229466122171	1.76E-7	8.61E-6	8.61E-6	1
276	Mical2	17.2911151	68.77225433	-1.991795726349	-1.8108132165803	-5.217275050624	1.82E-7	8.85E-6	8.85E-6	1
277	Thsd4	11.40978343	55.94817765	-2.2938197323724	-2.1128372226038	-5.2105858995134	1.88E-7	9.14E-6	9.14E-6	1
278	Cd109	30.93580456	94.54613392	-1.6117409110354	-1.4307584012668	-5.1625832450663	2.44E-7	1.18E-5	1.18E-5	1
279	Adamts9	30.81817793	3.8975135	2.9831556424191	3.1641381521877	5.1392405728974	2.76E-7	1.33E-5	1.33E-5	1
280	Cd248	114.0978343	57.83407128	0.98027983739067	1.1612623471593	5.1355710429541	2.81E-7	1.35E-5	1.35E-5	1
281	Ncam1	18.23212816	69.65233802	-1.9336888096241	-1.7527062998554	-5.1335076800151	2.84E-7	1.36E-5	1.36E-5	1
282	Atp2a2	95.74807951	200.7848083	-1.0683346615621	-0.88735215179344	-5.1273594974402	2.94E-7	1.40E-5	1.40E-5	1
283	Scarf2	144.3278791	81.97350973	0.81612033106642	0.99710284083508	5.1027924672514	3.35E-7	1.59E-5	1.59E-5	1
284	Ldha	165.6182997	303.3774218	-0.87325163049031	-0.69226912072164	-5.0867349044444	3.64E-7	1.73E-5	1.73E-5	1
285	Thbd	57.16654379	138.6760448	-1.2784756202429	-1.0974931104743	-5.0814319234843	3.75E-7	1.77E-5	1.77E-5	1
286	Ghitm	56.69603725	137.2930562	-1.2759388537573	-1.0949563439886	-5.0465552295471	4.50E-7	2.12E-5	2.12E-5	1
287	Vkorc1	56.34315735	18.10457884	1.6378857951888	1.8188683049575	5.0433362123886	4.57E-7	2.14E-5	2.14E-5	1
288	Fosl2	35.75849652	101.4610772	-1.5045683983513	-1.3235858885826	-5.0402316432245	4.65E-7	2.17E-5	2.17E-5	1
289	Matn2	57.04891715	18.6074838	1.6163165229488	1.7972990327175	5.0334274118124	4.82E-7	2.24E-5	2.24E-5	1
290	Siglec1	24.70159299	1.760167387	3.8108195465283	3.991802056297	5.0289879811925	4.93E-7	2.29E-5	2.28E-5	1
291	Pmepa1	28.23039199	87.63119062	-1.6341952991977	-1.4532127894291	-5.0285711537751	4.94E-7	2.28E-5	2.28E-5	1
292	Dst	42.34558799	112.776439	-1.4131821272994	-1.2321996175307	-5.0260000100912	5.01E-7	2.31E-5	2.31E-5	1
293	Sqstm1	167.1474459	101.838256	0.71484169186292	0.89582420163159	5.021140530157	5.14E-7	2.36E-5	2.36E-5	1
294	Col11a2	66.69430108	24.8937959	1.4217772560415	1.6027597658101	5.019710894008	5.17E-7	2.37E-5	2.37E-5	1
295	Srpx2	54.34350459	17.0987689	1.668215151597	1.8491976613656	5.0092155720158	5.47E-7	2.49E-5	2.49E-5	1
296	P3h3	128.4482836	70.53242172	0.86482913185436	1.045811641623	5.0065139422047	5.54E-7	2.52E-5	2.52E-5	1
297	Wwc2	22.46668696	76.31582885	-1.764194927132	-1.5832124173634	-4.9985422423522	5.78E-7	2.62E-5	2.62E-5	1
299	Lipa	71.63461968	28.66558316	1.3213373548283	1.5023198645969	4.9619432379822	6.98E-7	3.14E-5	3.14E-5	1
300	Huwe1	67.63531415	153.5117414	-1.1825003880563	-1.0015178782877	-4.9607206994474	7.02E-7	3.15E-5	3.15E-5	1
301	Rtn4	195.024958	341.8496518	-0.80970319350235	-0.62872068373368	-4.9585388639981	7.10E-7	3.17E-5	3.17E-5	1
302	Lamc1	80.33899055	173.3764876	-1.1097360218571	-0.9287535120884	-4.9510575596699	7.38E-7	3.29E-5	3.29E-5	1
303	Itm2c	160.4427278	97.43783749	0.7195043798357	0.90048688960437	4.9409731173317	7.77E-7	3.45E-5	3.45E-5	1
304	Synm	24.93684626	2.137346113	3.5443865642864	3.725369074055	4.9384510480993	7.87E-7	3.48E-5	3.48E-5	1
305	Kpnb1	116.6856202	228.3188553	-0.96842322595726	-0.78744071618859	-4.9369309068634	7.94E-7	3.50E-5	3.50E-5	1
306	Hspa8	91.74877398	190.6009828	-1.0547947735068	-0.87381226373811	-4.930916112679	8.18E-7	3.60E-5	3.59E-5	1
307	Col9a3	64.34176842	24.01371221	1.421897145863	1.6028796556317	4.9306402126709	8.20E-7	3.59E-5	3.59E-5	1
308	Cd68	28.23039199	3.646061016	2.9528385514455	3.1338210612142	4.8972661849734	9.72E-7	4.24E-5	4.24E-5	1
309	Cdsn	0	23.51080724	-6.0580030076232	-5.8770204978545	-4.8935061610704	9.91E-7	4.31E-5	4.31E-5	1
310	Rcc2	40.34593522	107.1187581	-1.4087159027143	-1.2277333929456	-4.8843060194556	1.04E-6	4.50E-5	4.50E-5	1
312	Pth1r	42.11033472	10.81245681	1.9614799730564	2.1424624828251	4.8556064911541	1.20E-6	5.17E-5	5.17E-5	1
313	Fads3	15.05620906	59.71996491	-1.9878547522066	-1.8068722424379	-4.8544961987639	1.21E-6	5.19E-5	5.19E-5	1
314	Ptpn14	49.28555935	121.7030022	-1.3041278527151	-1.1231453429464	-4.8498880365481	1.24E-6	5.29E-5	5.29E-5	1
315	Slc20a1	13.29180956	55.69672517	-2.0670549752467	-1.8860724654781	-4.8268948170527	1.39E-6	5.92E-5	5.92E-5	1
316	Smpd3	21.40804726	1.131536177	4.2417985902663	4.422781100035	4.8139052636814	1.48E-6	6.30E-5	6.30E-5	1
317	Txnrd1	42.46321462	109.633283	-1.3684003473427	-1.1874178375741	-4.8125645655222	1.49E-6	6.32E-5	6.32E-5	1
318	Plod3	86.45557548	180.0399784	-1.0582863860362	-0.87730387626749	-4.8085432863788	1.52E-6	6.43E-5	6.43E-5	1
319	Bicc1	87.27896191	41.23820735	1.0816523232108	1.2626348329795	4.7985345645499	1.60E-6	6.74E-5	6.74E-5	1
320	Ppfibp1	98.92399861	198.521736	-1.0049045144036	-0.82392200463497	-4.7862687854271	1.70E-6	7.14E-5	7.14E-5	1
321	Slc38a10	163.5010203	102.3411609	0.67591313497524	0.85689564474391	4.7824097565643	1.73E-6	7.26E-5	7.26E-5	1
322	Eif4ebp1	12.58604976	53.55937906	-2.0893136830427	-1.908331173274	-4.7707883716774	1.84E-6	7.65E-5	7.64E-5	1
323	Slc1a4	12.58604976	53.55937906	-2.0893136830427	-1.908331173274	-4.7707883716774	1.84E-6	7.65E-5	7.64E-5	1
324	Ifit3	20.70228746	1.005809935	4.3633605702913	4.54434308006	4.7626114181754	1.91E-6	7.93E-5	7.93E-5	1
325	Unc93b1	28.11276536	4.148965983	2.7604016400076	2.9413841497762	4.7425002518597	2.11E-6	8.74E-5	8.74E-5	1
326	Chac1	1.293892966	24.51661717	-4.2439697439945	-4.0629872342259	-4.7307106910479	2.24E-6	9.23E-5	9.23E-5	1
327	Cars	14.35044926	56.70253511	-1.9823173348643	-1.8013348250957	-4.7202865124247	2.36E-6	9.69E-5	9.69E-5	1
328	Xpot	27.52463219	81.97350973	-1.5744344835372	-1.3934519737686	-4.7120589578442	2.45E-6	0.00010055030192691	0.00010055030192691	1
330	Malat1	121.6259388	229.9532965	-0.91888993880003	-0.73790742903137	-4.6829606018791	2.83E-6	0.0001152379102343	0.0001152379102343	1
331	Rrm2	8.116237698	42.62119601	-2.3926880550817	-2.211705545313	-4.6797484816911	2.87E-6	0.00011670443304683	0.00011635729199571	1
332	Dlc1	28.11276536	82.60214094	-1.5549538010563	-1.3739712912877	-4.6797407665696	2.87E-6	0.00011635729199571	0.00011635729199571	1
333	Sars	40.46356186	103.9756021	-1.3615498135509	-1.1805673037822	-4.6652133112955	3.08E-6	0.00012451312508975	0.00012451312508975	1
334	Bcat1	5.763705032	36.71206264	-2.6711857634712	-2.4902032537025	-4.6597192956141	3.17E-6	0.00012750010115315	0.00012750010115315	1
335	Ly6e	57.63705032	21.62491361	1.414302135585	1.5952846453536	4.6506514515257	3.31E-6	0.00013283924385637	0.00013283924385637	1
336	Mme	38.34628246	9.80664687	1.9672548866849	2.1482373964536	4.6413452558106	3.46E-6	0.00013855199723952	0.00013855199723952	1
337	Ndufa4l2	18.7026347	0	5.2251696163841	5.4061521261528	4.6381618729018	3.52E-6	0.00014028521605474	0.00013990848234635	1
338	Cebpa	39.87542869	10.68673056	1.899679478671	2.0806619884397	4.6381052559436	3.52E-6	0.00013990848234635	0.00013990848234635	1
339	Cybb	23.52532666	2.514524838	3.2258570463102	3.4068395560789	4.635453188792	3.56E-6	0.00014129635230863	0.00014129635230863	1
340	Slpi	18.58500806	0	5.2077096983438	5.3886922081125	4.6225858747562	3.79E-6	0.0001499111927282	0.0001499111927282	1
341	Prep	13.99756936	54.81664148	-1.9694376106297	-1.788455100861	-4.6182310792173	3.87E-6	0.00015264225648023	0.00015264225648023	1
342	Epb4.1l3	10.9392769	48.2788769	-2.1418747380922	-1.9608922283235	-4.6120423290717	3.99E-6	0.00015679951919146	0.00015679951919146	1
343	Nomo1	48.22691965	115.9195951	-1.2652138904396	-1.0842313806709	-4.6001525623532	4.22E-6	0.00016553704653466	0.00016553704653466	1
344	Itgav	88.10234835	178.279811	-1.0168909571071	-0.8359084473384	-4.5920277813806	4.39E-6	0.00017161546281236	0.00017161546281236	1
345	Hs6st2	77.98645788	162.8154833	-1.0619423713496	-0.88095986158095	-4.5888043812359	4.46E-6	0.0001737813243571	0.0001737813243571	1
346	Rtp4	19.99652766	1.257262419	3.9913917926011	4.1723743023697	4.5837315558211	4.57E-6	0.00017753867645808	0.00017753867645808	1
347	Nxn	35.75849652	94.67186017	-1.4046495902287	-1.22366708046	-4.5797376260005	4.66E-6	0.00018044123418922	0.00018044123418922	1
348	Ptgs2	2.234906033	26.02533208	-3.5416304928106	-3.3606479830419	-4.5533337768693	5.28E-6	0.00020406305143432	0.00020406305143432	1
349	C1qb	27.40700556	4.526144709	2.5981900945015	2.7791726042702	4.550488403526	5.35E-6	0.00020624961352464	0.00020624961352464	1
350	Ifitm3	128.5659102	76.44155509	0.75007912340665	0.93106163317532	4.5488085932205	5.40E-6	0.00020730859398966	0.00020730859398966	1
351	Gpm6b	26.81887239	4.274692225	2.6493561240732	2.8303386338418	4.5438023453337	5.52E-6	0.00021169134418016	0.00021169134418016	1
352	Sptan1	114.0978343	215.8719574	-0.91990443590303	-0.73892192613437	-4.5426790142306	5.55E-6	0.0002122183185821	0.0002122183185821	1
353	Esm1	22.81956686	2.514524838	3.18191369871	3.3628962084787	4.5409512128914	5.60E-6	0.0002133590149182	0.0002133590149182	1
354	Bsg	248.5450762	181.5486933	0.45315097671459	0.63413348648326	4.5358998053106	5.74E-6	0.00021791334064191	0.00021791334064191	1
355	Creg1	45.40388046	14.58424406	1.6384049938	1.8193875035686	4.5281878573496	5.95E-6	0.00022538130133221	0.00022538130133221	1
356	C1s1	31.75919099	6.789217064	2.2258570459673	2.406839555736	4.5249818550354	6.04E-6	0.00022818226053109	0.00022818226053109	1
357	Vcl	126.3310042	233.0964525	-0.88371829891611	-0.70273578914744	-4.5176089249656	6.25E-6	0.00023560936643972	0.00023560936643972	1
358	Crtap	143.0339861	89.01417928	0.68425091461621	0.86523342438488	4.5099601073751	6.48E-6	0.00024358399691441	0.00024358399691441	1
359	Lhfp	62.22448902	136.664425	-1.1350833619682	-0.95410085219949	-4.4957187506135	6.93E-6	0.00025974677261665	0.00025974677261665	1
360	Jak1	72.57563275	152.7573839	-1.0736849677631	-0.89270245799439	-4.4948439142547	6.96E-6	0.00026009243948904	0.00026009243948904	1
362	Slfn5	17.9968749	0	4.5763542926557	4.7573368024244	4.480199363904	7.46E-6	0.00027705441841469	0.00027705441841469	1
363	Atf4	49.40318599	115.7938688	-1.2288828770114	-1.0479003672427	-4.4716662785596	7.76E-6	0.00028755102478249	0.00028755102478249	1
364	Kazald1	34.34697692	8.423658209	2.0276643194028	2.2086468291714	4.4691260778437	7.85E-6	0.0002901874054217	0.00029010543131611	1
365	S1pr1	42.58084126	13.2012554	1.6895293209683	1.8705118307369	4.468599601648	7.87E-6	0.00029010543131611	0.00029010543131611	1
366	Xist	124.448978	229.198939	-0.88104598296885	-0.70006347320018	-4.4646939844269	8.02E-6	0.00029464066448504	0.00029464066448504	1
367	Wisp2	55.28451765	125.0976107	-1.1781068175788	-0.99712430781013	-4.4617668072712	8.13E-6	0.00029788126402872	0.00029788126402872	1
369	Angpt1	19.52602113	1.508714903	3.6940058820199	3.8749883917886	4.4291124477666	9.46E-6	0.00034486910368411	0.00034486910368411	1
370	Gpc3	21.05516736	66.25772949	-1.6539144231875	-1.4729319134188	-4.4166650373473	1.00E-5	0.00036434204543955	0.00036434204543955	1
371	Dstn	66.92955435	142.4478321	-1.089718352318	-0.90873584254931	-4.4061621303761	1.05E-5	0.00038142314073612	0.00038142314073612	1
372	Fkbp7	39.05204226	11.44108801	1.7711737430993	1.952156252868	4.4034614194228	1.07E-5	0.00038516647935858	0.00038516647935858	1
373	Tnfrsf19	42.46321462	13.57843413	1.6448964755924	1.8258789853611	4.3897668374305	1.13E-5	0.00040913899518327	0.00040913899518327	1
374	Mybbp1a	32.58257743	86.49965444	-1.4085936371823	-1.2276111274136	-4.3886864293666	1.14E-5	0.00041007710589411	0.00041007710589411	1
375	Irgm2	20.4670342	2.011619871	3.3468724472501	3.5278549570188	4.3843243447177	1.16E-5	0.00041726443428139	0.00041726443428139	1
376	Csrp1	57.40179705	127.1092306	-1.1469009933711	-0.96591848360243	-4.3803831544811	1.18E-5	0.00042375369234653	0.00042375369234653	1
377	Lamb2	97.39485238	187.8350054	-0.94754852376522	-0.76656601399655	-4.3747968702164	1.22E-5	0.00043359863856304	0.00043359863856304	1
378	Cspg4	19.0555146	61.98303727	-1.7016648819711	-1.5206823722025	-4.3739400589553	1.22E-5	0.00043415327811445	0.00043415327811445	1
379	Aldh18a1	26.11311259	74.93284018	-1.5208237029792	-1.3398411932105	-4.3722374540129	1.23E-5	0.00043639933771728	0.00043639933771728	1
380	Cd34	25.52497943	4.400418467	2.5361971669789	2.7171796767475	4.3398809698774	1.43E-5	0.00050454955119736	0.00050454955119736	1
382	Pld4	17.87924826	1.131536177	3.9819314634225	4.1629139731912	4.3315396029193	1.48E-5	0.00052130826314697	0.00052130826314697	1
383	Npm1	63.40075535	135.658615	-1.0974087351757	-0.91642622540698	-4.3304593653294	1.49E-5	0.00052250454869471	0.00052250454869471	1
384	Dusp1	5.646078399	33.31745411	-2.5609570974347	-2.379974587666	-4.3243790385274	1.53E-5	0.00053572587131191	0.00053572587131191	1
385	Pdcd6ip	63.40075535	135.5328888	-1.096071048886	-0.91508853911738	-4.3231357659184	1.54E-5	0.00053735568348639	0.00053735568348639	1
388	Cd36	28.46564526	6.034859612	2.237829687856	2.4188121976247	4.2963092929632	1.74E-5	0.00060196488599514	0.00060196488599514	1
390	Rnase4	67.51768752	31.30583424	1.1088339458364	1.2898164556051	4.290990208362	1.78E-5	0.00061340598947373	0.00061340598947373	1
391	Serpine2	159.2664615	106.1129482	0.58584178590268	0.76682429567135	4.2903787424899	1.78E-5	0.00061352431470549	0.00061352431470549	1
392	Aoc3	15.99722213	0	5.9913917916339	6.1723743014026	4.2886055051473	1.80E-5	0.00061686442164693	0.00061686442164693	1
393	Csf1	137.7407876	244.1603618	-0.82587317361385	-0.64489066384519	-4.2858184611324	1.82E-5	0.00062306042699024	0.00062306042699024	1
394	Dmp1	15.99722213	0	4.9997495020495	5.1807320118181	4.2744875373432	1.92E-5	0.00065394028549579	0.00065394028549579	1
395	Slc11a1	21.17279399	2.64025108	3.0034646246466	3.1844471344153	4.272011045975	1.94E-5	0.00065957293344614	0.00065957293344614	1
396	Pdlim5	62.69499555	133.5212689	-1.0906473766206	-0.9096648668519	-4.2695037893213	1.96E-5	0.00066534621550084	0.00066534621550084	1
397	Adamtsl3	76.69256491	154.89473	-1.0141294348773	-0.83314692510865	-4.2680670769886	1.97E-5	0.00066795811579247	0.00066783203539261	1
398	Gbp3	17.76162163	1.257262419	3.8204055959987	4.0013881057673	4.2675478450145	1.98E-5	0.00066783203539261	0.00066783203539261	1
399	Egfr	51.16758549	19.99047247	1.3559175864313	1.5369000962	4.2644146616129	2.00E-5	0.00067557437191975	0.00067557437191975	1
400	Fam101b	46.69777342	17.0987689	1.4494613071774	1.6304438169461	4.2523385115018	2.12E-5	0.00071128318016555	0.00071128318016555	1
401	Slc38a1	9.880637198	42.11829104	-2.0917709111466	-1.9107884013779	-4.2342633341709	2.29E-5	0.00076904844668828	0.00076904844668828	1
402	Tmtc1	32.34732416	8.423658209	1.9411275691975	2.1221100789661	4.2301070125337	2.34E-5	0.00078144768407069	0.00078144768407069	1
403	Hr	17.17348846	1.131536177	3.9238285088369	4.1048110186055	4.2282949656295	2.35E-5	0.00078581192678622	0.00078581192678622	1
404	Coro1c	25.99548596	72.79549407	-1.4855880273323	-1.3046055175636	-4.2217938444124	2.42E-5	0.00080682592316264	0.00080682592316264	1
405	Stat1	49.28555935	19.11038877	1.366807871509	1.5477903812777	4.206954874869	2.59E-5	0.0008595232661268	0.0008595232661268	1
406	Smarca2	67.51768752	32.06019169	1.0744824411161	1.2554649508848	4.2016491946531	2.65E-5	0.00087775437486665	0.00087775437486665	1
407	Kcns1	19.7612744	2.263072355	3.1263213726582	3.3073038824268	4.1960859864683	2.72E-5	0.00089737273301399	0.00089737273301399	1
408	Nid2	139.0346806	90.01998922	0.62712749443086	0.80811000419953	4.1942098094048	2.74E-5	0.00090261397200326	0.00090261397200326	1
409	Copg2	83.75016291	44.50708964	0.91205683207329	1.093039341842	4.1905281174325	2.78E-5	0.00091514336220041	0.00091514336220041	1
410	Ms4a7	16.5853553	1.005809935	4.0434803045174	4.224462814286	4.1886281926934	2.81E-5	0.00092058655628258	0.00092058655628258	1
411	Stk17b	25.40735279	4.903323435	2.3734142343003	2.554396744069	4.1869313902788	2.83E-5	0.00092523639280707	0.00092523639280707	1
412	Lonp1	23.87820656	68.52080185	-1.5208475513555	-1.3398650415868	-4.1810195493624	2.90E-5	0.00094732180229128	0.00094732180229128	1
413	Tspan8	15.29146233	0	4.9346544738137	5.1156369835824	4.173435573612	3.00E-5	0.00097705693477472	0.00097705693477472	1
414	Slc25a3	83.04440311	162.5640308	-0.96905323531951	-0.78807072555084	-4.1683675669306	3.07E-5	0.00099661938624746	0.00099661938624746	1
415	Wars	11.2921568	44.3813634	-1.9746329210206	-1.793650411252	-4.1637523804007	3.13E-5	0.0010145394943258	0.0010145394943258	1
416	Eln	78.69221768	40.86102862	0.94549544410241	1.1264779538711	4.1620685853847	3.15E-5	0.0010195945196132	0.0010195945196132	1
418	Klhl13	30.58292466	7.795026999	1.9721004539367	2.1530829637054	4.1508100882781	3.31E-5	0.0010659477341655	0.0010659477341655	1
419	Tubb6	46.34489352	105.6100432	-1.1882647468478	-1.0072822370791	-4.1339319083532	3.57E-5	0.0011446388329561	0.0011446388329561	1
420	Itgb2	20.4670342	2.765977322	2.8874408289388	3.0684233387075	4.1293687393181	3.64E-5	0.0011648134205774	0.0011648134205774	1
421	Fasn	43.05134779	100.2038148	-1.2188071242919	-1.0378246145232	-4.1269019101249	3.68E-5	0.0011745772993557	0.0011745772993557	1
422	Vars	27.05412566	73.42412528	-1.4404055566638	-1.2594230468951	-4.1253200019127	3.70E-5	0.0011798776946991	0.0011781824815181	1
424	Fermt2	45.63913372	104.2270546	-1.1913864987967	-1.0104039890281	-4.1172686219521	3.83E-5	0.0012160849656675	0.0012160849656675	1
425	Cd200	15.1738357	0	4.5932281112201	4.7742106209888	4.1163648859803	3.85E-5	0.0012179882541916	0.0012179882541916	1
426	Lrrc59	74.69291215	148.9855967	-0.99612961108595	-0.81514710131729	-4.1082008441857	3.99E-5	0.001258880936787	0.0012582900447051	1
428	Galnt2	43.87473422	101.2096247	-1.205884200933	-1.0249016911643	-4.1051059720891	4.04E-5	0.0012698922148636	0.0012698922148636	1
429	Mtpn	103.9819438	191.9839714	-0.88465283663921	-0.70367032687054	-4.1044909746618	4.05E-5	0.0012703069227773	0.0012703069227773	1
430	Gls	35.28798999	87.12828565	-1.3039639004387	-1.12298139067	-4.1029335734707	4.08E-5	0.0012759172712747	0.0012740220345607	1
431	Tmpo	23.99583319	67.7664444	-1.497787169889	-1.3168046601204	-4.1027401330309	4.08E-5	0.0012740220345607	0.0012740220345607	1
432	H2-Q4	17.87924826	1.760167387	3.3445015423519	3.5254840521206	4.0967150042863	4.19E-5	0.0013045974612949	0.0013045974612949	1
433	Tcn2	47.40353322	18.6074838	1.349111614418	1.5300941241866	4.0911976900643	4.29E-5	0.0013329453158598	0.0013329453158598	1
434	S1pr3	38.93441562	13.07552916	1.574176639739	1.7551591495076	4.0904168106202	4.31E-5	0.0013343597078338	0.0013343597078338	1
435	Lats2	37.99340256	91.40297788	-1.2664922479423	-1.0855097381736	-4.0886379067832	4.34E-5	0.0013415410113801	0.0013394844216189	1
436	Tns1	82.45626995	44.50708964	0.88959403522785	1.0705765449965	4.088461105367	4.34E-5	0.0013394844216189	0.0013394844216189	1
437	S100a6	58.93094329	124.5947057	-1.0801455021392	-0.89916299237056	-4.0840902765114	4.42E-5	0.0013618213287269	0.0013618213287269	1
438	Uggt1	40.81644176	95.92912259	-1.2328184429655	-1.0518359331968	-4.0824859781745	4.46E-5	0.0013681287303096	0.0013681287303096	1
439	Col15a1	17.76162163	1.760167387	3.3349787685006	3.5159612782692	4.0789126848597	4.52E-5	0.0013861607225622	0.0013861607225622	1
440	Vgll3	40.69881512	95.6776701	-1.2331954647204	-1.0522129549517	-4.0783257418713	4.54E-5	0.0013865057807275	0.0013865057807275	1
441	Acan	13.87994273	48.65605562	-1.8096177554367	-1.628635245668	-4.07342900864	4.63E-5	0.0014127847209896	0.0014127847209896	1
442	Cd63	160.3251012	110.3876404	0.53842166864738	0.71940417841605	4.0717595275631	4.67E-5	0.0014197317090167	0.0014197317090167	1
443	Ptprn	1.0586397	18.35603132	-4.1159706058104	-3.9349880960417	-4.053363305512	5.05E-5	0.0015327155850073	0.0015327155850073	1
444	Col27a1	27.28937893	6.412038338	2.0894846045641	2.2704671143327	4.0514368828473	5.09E-5	0.00154191144903	0.00154191144903	1
445	Slit3	105.3934634	63.49175217	0.73114429509899	0.91212680486765	4.0479157221061	5.17E-5	0.0015617687622724	0.0015617687622724	1
446	Hnrnpab	131.8594559	230.4562014	-0.80549155661526	-0.6245090468466	-4.0464173910802	5.20E-5	0.0015682699852607	0.0015682699852607	1
447	Fxyd1	14.70332916	0	4.5477851398048	4.7287676495735	4.0452028823523	5.23E-5	0.001572896066401	0.001572896066401	1
448	Ipo7	21.52567389	62.61166848	-1.5403731429405	-1.3593906331719	-4.0411951450159	5.32E-5	0.0015964527715704	0.0015964527715704	1
449	Ubr4	65.98854128	134.5270789	-1.0276091700038	-0.84662666023512	-4.0323992141937	5.52E-5	0.0016537266356655	0.0016537266356655	1
450	Loxl2	57.04891715	120.8229185	-1.0826227326962	-0.90164022292754	-4.0311299050815	5.55E-5	0.0016589894691811	0.001658749314273	1
451	Npc2	136.0940147	89.76853673	0.60032183598802	0.78130434575669	4.0306422535724	5.56E-5	0.001658749314273	0.001658749314273	1
453	Psmb8	15.5267156	1.005809935	3.948323071477	4.1293055812457	4.0273183119321	5.64E-5	0.0016749388153865	0.0016749388153865	1
454	Ctps	15.5267156	51.17058046	-1.720561913265	-1.5395794034963	-4.0103637604215	6.06E-5	0.0017959235948822	0.0017959235948822	1
455	Slc6a6	190.0846394	138.1731399	0.46016476258638	0.64114727235505	4.0054292829617	6.19E-5	0.001829801550956	0.001829801550956	1
456	Rras2	13.29180956	46.77016199	-1.8150508976835	-1.6340683879148	-4.0032520071307	6.25E-5	0.0018426807684261	0.0018426807684261	1
457	Nrgn	14.115196	0	4.8108195462927	4.9918020560614	3.9975116251486	6.40E-5	0.0018837972583726	0.0018837972583726	1
458	Ybx1	111.627675	200.6590821	-0.84605170799878	-0.66506919823011	-3.9926808911328	6.53E-5	0.0019184047226487	0.0019184047226487	1
459	Meox2	20.23178093	3.143156048	2.6863375162919	2.8673200260606	3.9725465690654	7.11E-5	0.0020835205071812	0.0020835205071812	1
460	Prrc2c	37.05238949	88.13409559	-1.2501336644773	-1.0691511547086	-3.9655709166447	7.32E-5	0.0021407439315372	0.0021407439315372	1
461	Slc6a9	1.882026133	20.24192495	-3.4269879268307	-3.246005417062	-3.9564910082906	7.61E-5	0.0022189026592034	0.0022189026592034	1
462	Trem2	15.05620906	1.005809935	3.9039289514798	4.0849114612484	3.9534891349053	7.70E-5	0.0022420753049283	0.0022420753049283	1
463	Macf1	75.39867195	147.2254293	-0.96541586271363	-0.78443335294496	-3.9509574483831	7.78E-5	0.0022610343911257	0.0022610343911257	1
464	Rnf128	19.7612744	3.017429806	2.7112838736981	2.8922663834667	3.9431560320494	8.04E-5	0.002330859464977	0.002330859464977	1
465	Adam9	46.93302669	103.5984233	-1.1423266390801	-0.9613441293114	-3.9388733165015	8.19E-5	0.0023677510869962	0.0023677510869962	1
466	Tnk2	10.70402363	40.86102862	-1.932572316423	-1.7515898066543	-3.930051072383	8.49E-5	0.0024510606360372	0.0024510606360372	1
468	Plxnc1	13.17418293	45.76435206	-1.7965107669392	-1.6155282571706	-3.9276384777842	8.58E-5	0.0024651910578441	0.0024651910578441	1
469	Sod3	32.22969753	9.80664687	1.716558815516	1.8975413252846	3.925409587426	8.66E-5	0.0024828255289523	0.0024828255289523	1
470	Top2a	26.70124576	70.28096923	-1.3962270342429	-1.2152445244743	-3.9243981887721	8.69E-5	0.002487974011673	0.002487974011673	1
471	Sirpa	56.93129052	26.52823705	1.1016929995663	1.282675509335	3.9232472098247	8.74E-5	0.0024945875105124	0.0024945875105124	1
472	Podxl2	27.17175229	6.914943306	1.9743182788792	2.1553007886479	3.9149949432057	9.04E-5	0.0025759993098422	0.0025759993098422	1
473	Mbnl2	53.52011815	113.4050702	-1.0833319368658	-0.90234942709709	-3.9079855775858	9.31E-5	0.0026462644916986	0.0026462644916986	1
474	Entpd2	14.115196	0	4.2258570455716	4.4068395553402	3.9055557769009	9.40E-5	0.0026673586297194	0.0026673586297194	1
475	Clic4	104.9229569	189.2179941	-0.85071892066218	-0.66973641089352	-3.9011821136349	9.57E-5	0.0027103020077776	0.0027103020077776	1
476	Thra	51.75571865	23.00790227	1.1695888264635	1.3505713362322	3.8925786670802	9.92E-5	0.002802373849958	0.002802373849958	1
477	Atp1a1	95.98333278	176.1424649	-0.87588694691267	-0.694904437144	-3.8883617782284	0.00010092311813451	0.0028455241421195	0.0028455241421195	1
478	Cyp1b1	51.87334529	110.5133666	-1.0911555576394	-0.91017304787069	-3.8860023054614	0.00010190853873478	0.0028672969402595	0.0028672969402595	1
479	Kcnk2	13.7623161	46.39298327	-1.7531833349221	-1.5722008251534	-3.8774719314377	0.0001055474999461	0.0029634829369	0.0029634829369	1
481	Zmiz1	35.99374979	85.11666578	-1.2416952296837	-1.060712719915	-3.8719838485471	0.00010795310726756	0.0030184227435374	0.0030184227435374	1
482	Gaa	150.444464	104.8556858	0.52082592618678	0.70180843595545	3.8595280364142	0.0001136062233579	0.0031698964687561	0.0031698964687561	1
483	Abce1	29.64191159	74.42993522	-1.3282444910787	-1.14726198131	-3.8578527540348	0.00011438752146968	0.0031850885636557	0.0031850885636557	1
484	Atp11a	36.46425632	85.61957075	-1.2314576317049	-1.0504751219363	-3.8527565705789	0.00011679549088534	0.0032454185060266	0.0032454185060266	1
485	Pdlim2	40.11068196	15.21287527	1.398693643332	1.5796761531007	3.8520347538226	0.00011714039255614	0.0032482910092526	0.0032457786601752	1
486	Scara3	64.22414178	32.56309666	0.97987780426573	1.1608603140344	3.8517199134844	0.00011729113159678	0.0032457786601752	0.0032457786601752	1
487	Itga10	22.93719349	4.903323435	2.2258570458253	2.406839555594	3.8454703384024	0.00012032141957082	0.0033227982994002	0.0033227982994002	1
488	Prpf8	71.51699305	139.5561285	-0.96448749620535	-0.78350498643669	-3.8427066173764	0.00012168489672456	0.0033535659345259	0.0033535659345259	1
489	Ezr	18.82026133	55.44527269	-1.5587777994088	-1.3777952896401	-3.8420830980738	0.00012199451641865	0.003355223417821	0.003355223417821	1
490	Itga5	39.52254879	90.39716794	-1.1936015864157	-1.012619076647	-3.8412663227368	0.00012240122466553	0.0033595389194424	0.0033595389194424	1
491	Tnfrsf12a	15.1738357	48.65605562	-1.6810335490288	-1.5000510392601	-3.8363665667948	0.0001248679887759	0.0034202639125196	0.0034202639125196	1
492	Lgr4	13.29180956	45.00999461	-1.7597078640551	-1.5787253542864	-3.8307515152311	0.00012775247047405	0.0034921605191169	0.0034921605191169	1
493	Maff	3.411172366	23.51080724	-2.7849845134987	-2.6040020037301	-3.8232051605309	0.00013172808498874	0.0035935314706156	0.0035935314706156	1
494	Sh3pxd2a	205.4937284	155.7748137	0.39963237250443	0.58061488227309	3.8112926440725	0.00013824199068312	0.003763596220035	0.003763596220035	1
495	Ergic1	46.81540006	101.4610772	-1.1158712909188	-0.93488878115009	-3.8081728446976	0.00013999740746617	0.003803687137399	0.003803687137399	1
498	Pmp22	60.57771615	30.17429806	1.0054669777056	1.1864494874743	3.8063038981704	0.00014105904100856	0.0038094438604901	0.0038094438604901	1
499	Fhdc1	3.528798999	23.63653348	-2.7437693048172	-2.5627867950485	-3.7997827241582	0.00014482300626512	0.0039032557339872	0.0039032557339872	1
500	Rassf4	15.64434223	1.634441145	3.2587716686196	3.4397541783883	3.794895905481	0.00014770541369495	0.0039729802175668	0.0039729802175668	1
501	Trim35	67.04718098	132.012554	-0.97742655215467	-0.79644404238601	-3.7905840652861	0.00015029345353099	0.0040345242645475	0.0040270998886339	1
502	Serbp1	104.0995705	185.8233856	-0.83596795790153	-0.65498544813286	-3.7905462861078	0.00015031631675918	0.0040270998886339	0.0040270998886339	1
505	Epas1	19.7612744	3.520334774	2.488891452225	2.6698739619937	3.7829757273938	0.00015496453137186	0.0041269663018221	0.0041269663018221	1
506	Btbd3	29.17140506	8.675110693	1.7496008047947	1.9305833145634	3.7778516695586	0.00015818704367094	0.004204461561918	0.004204461561918	1
507	Cep170b	30.46529803	74.6813877	-1.2935818816606	-1.1125993718919	-3.7701909483649	0.00016312269190707	0.0043270948391681	0.0043270948391681	1
508	Plek	19.4083945	3.394608532	2.5153636636165	2.6963461733852	3.7688893641297	0.00016397554372014	0.0043411556840397	0.0043411556840397	1
509	Fzd1	124.0960981	82.97931967	0.58063402012721	0.76161652989588	3.7646565712114	0.00016677814080175	0.0044066782232668	0.0044066782232668	1
510	Eef1g	60.57771615	121.8287284	-1.0079952818967	-0.82701277212803	-3.7611805628618	0.00016911329304568	0.0044596170160224	0.0044538675574682	1
511	Itm2a	136.9174012	94.29468144	0.53805750912725	0.71904001889591	3.7610132939505	0.00016922643481792	0.0044538675574682	0.0044538675574682	1
512	Hpgd	12.3507965	0	5.0332119676292	5.2141944773979	3.7582579682659	0.00017110043202473	0.0044943939654308	0.0044943939654308	1
513	Mki67	16.70298193	50.66767549	-1.6009599576019	-1.4199774478333	-3.7576818298879	0.00017149474427073	0.0044959704009689	0.0044959704009689	1
515	Srpx	56.34315735	27.53404698	1.0330237373356	1.2140062471043	3.7382049355362	0.00018533884493147	0.0048400429621035	0.0048400429621035	1
516	Pi15	12.46842313	0	4.6402071152772	4.8211896250459	3.7375641250725	0.0001858117087761	0.0048429877351351	0.0048429877351351	1
517	Fmo1	12.46842313	0	4.6318494048617	4.8128319146304	3.7364925360312	0.00018660498547393	0.0048542561888568	0.0048542561888568	1
518	Prrx2	47.75641312	101.838256	-1.0925132300221	-0.91153072025339	-3.7350135938353	0.00018770504767624	0.004873446305401	0.004873446305401	1
519	Olfml1	12.11554323	0	5.0054669767494	5.186449486518	3.7203301452383	0.00019896251757626	0.0051557743716437	0.0051431168456852	1
520	Fam43a	28.93615179	8.800836934	1.7171604395635	1.8981429493321	3.7202180716932	0.00019905083165352	0.0051481435286695	0.0051431168456852	1
521	Arhgap29	39.64017542	88.88845304	-1.1650326725522	-0.98405016278348	-3.7199795706415	0.00019923889334538	0.0051431168456852	0.0051431168456852	1
522	Kif5b	59.04856992	118.8112986	-1.0086980137064	-0.8277155039377	-3.7170012870635	0.00020160141674847	0.0051941330533529	0.0051941330533529	1
523	F2r	45.75676036	98.44364742	-1.1053132008636	-0.92433069109493	-3.7155364604426	0.00020277302196524	0.0052143295839589	0.0052143295839589	1
524	Fam120a	90.69013428	165.2042819	-0.86523355927275	-0.68425104950409	-3.7147721474676	0.00020338687518592	0.005220133748808	0.005220133748808	1
526	Sorbs1	24.11345983	62.9888472	-1.385257742243	-1.2042752324743	-3.6886771442791	0.00022542305130771	0.0057637160019721	0.0057637160019721	1
527	Capn6	44.81574729	19.4875675	1.2014517333217	1.3824342430904	3.6872210807754	0.00022671637741158	0.0057857847434695	0.0057857847434695	1
528	Mcm2	8.704370865	34.44899029	-1.9846497661698	-1.8036672564011	-3.6824267730231	0.00023102423893888	0.0058845549043352	0.0058845549043352	1
529	Nckap1	47.05065332	99.95236233	-1.0870259092556	-0.90604339948692	-3.6814855280027	0.00023187895329899	0.00589516076166	0.00589516076166	1
530	Glipr2	11.2921568	39.60376621	-1.8103165662533	-1.6293340564847	-3.6761255832381	0.00023680298399082	0.0060089874182879	0.0060089874182879	1
531	Map6	10.2335171	37.46642009	-1.8722960729281	-1.6913135631594	-3.6719071667349	0.0002407471394514	0.0060975673794385	0.0060975673794385	1
532	Fuca1	50.22657242	23.51080724	1.0951267508932	1.2761092606618	3.6702788426462	0.0002422860191753	0.0061250087817456	0.0061250087817456	1
533	Cpd	38.81678899	86.87683317	-1.1622907349664	-0.98130822519771	-3.6691337237933	0.00024337375785792	0.0061409637325163	0.0061409637325163	1
534	Slc1a6	6.587091465	29.79711934	-2.1774593758436	-1.996476866075	-3.6663019805387	0.00024608331032051	0.0061977049447575	0.0061977049447575	1
535	Sema3b	25.52497943	7.040669548	1.8581252617023	2.039107771471	3.6629548310883	0.0002493225159558	0.006267548630074	0.0062571072326979	1
536	Gng12	35.87612316	82.09923597	-1.194344797696	-1.0133622879273	-3.6629035990279	0.00024937240513987	0.0062571072326979	0.0062571072326979	1
537	Rad23b	51.28521212	106.1129482	-1.0489859129685	-0.86800340319986	-3.6580492119648	0.00025414225671585	0.0063649147310455	0.0063649147310455	1
538	Omd	16.2324754	2.263072355	2.8425284066576	3.0235109164262	3.6519417410805	0.0002602649368128	0.0065061396564968	0.0065061396564968	1
539	Cct2	59.16619655	117.9312149	-0.99510057125763	-0.81411806148896	-3.6509650818727	0.00026125676132111	0.0065188166660625	0.0065188166660625	1
540	Pkd1	84.10304281	154.5175513	-0.87754081732122	-0.69655830755255	-3.6493915207071	0.00026286221389009	0.0065467294714959	0.0065467294714959	1
541	Pkd2	75.63392521	142.1963796	-0.91077933538787	-0.7297968256192	-3.6467987667864	0.00026552770650245	0.0066008911732928	0.0066008911732928	1
542	Hspd1	22.23143369	59.0913337	-1.4103455713321	-1.2293630615634	-3.6313256395938	0.00028196913015803	0.0069966841909508	0.0069966841909508	1
543	Trim66	0	13.2012554	-6.8103165699774	-6.6293340602087	-3.630682948939	0.00028267225295724	0.0070012138674438	0.0070012138674438	1
544	Iqgap1	78.10408451	145.4652619	-0.89720476657508	-0.71622225680641	-3.6284119408621	0.00028516998474374	0.007050093979446	0.007050093979446	1
545	Cd302	30.23004476	10.05809935	1.5876254061069	1.7686079158756	3.623427303612	0.00029072494118163	0.0071742380439482	0.0071742380439482	1
546	Ptgis	55.87265082	28.16267819	0.98835773242273	1.1693402421914	3.6134643415013	0.00030213292315854	0.0074420983215369	0.0074420983215369	1
547	Ptprf	41.87508146	90.90007291	-1.1181894546414	-0.93720694487273	-3.6119785696076	0.00030386968315793	0.0074711944584844	0.0074711944584844	1
548	Clec4d	15.40908896	2.011619871	2.9373519523147	3.1183344620833	3.6098950589197	0.00030632090856886	0.0075177187944208	0.0075177187944208	1
549	Mef2a	64.81227495	35.20334774	0.88055444275905	1.0615369525277	3.5996937511957	0.00031859217545535	0.0078046378282314	0.0077976396565023	1
550	Farp1	38.22865582	84.99093954	-1.1526545773026	-0.97167206753398	-3.5994537856173	0.00031888629720249	0.0077976396565023	0.0077976396565023	1
551	Rgs17	1.7643995	17.35022139	-3.2977049099865	-3.1167224002179	-3.5967872334091	0.0003221717950605	0.0078636814369667	0.0078636814369667	1
552	Ndnf	22.81956686	5.783407128	1.9802798373907	2.1612623471593	3.5939787479793	0.00032566641199656	0.0079345789401118	0.0079345789401118	1
553	Tnfaip2	41.99270809	18.10457884	1.2137842135649	1.3947667233336	3.593340913554	0.00032646500175238	0.0079396524567229	0.0079396524567229	1
554	Unc5c	15.76196886	47.14734072	-1.5807286439335	-1.3997461341648	-3.5856859272013	0.00033619337694235	0.0081614886759885	0.0081614886759885	1
555	Ppp1r9b	78.33933778	46.26725703	0.75974536214087	0.94072787190954	3.5814269060886	0.00034172274718519	0.0082807733817903	0.0082807733817903	1
556	Ssc5d	51.16758549	24.8937959	1.039443921986	1.2204264317547	3.5772142857643	0.00034727547638578	0.0084001940322164	0.0084001940322164	1
557	Tagln2	33.64121713	77.32163878	-1.200642311974	-1.0196598022054	-3.572899800926	0.00035304987757651	0.0085245382469058	0.0085245382469058	1
558	Sulf1	78.45696441	144.9623569	-0.88570489495806	-0.70472238518939	-3.5710859711335	0.00035550417236969	0.0085684150792113	0.0085588770679778	1
559	Hsp90aa1	37.75814929	83.85940336	-1.1511845128312	-0.97020200306249	-3.5709087423112	0.00035574483463451	0.0085588770679778	0.0085588770679778	1
560	Iigp1	11.17453016	0	4.8888220574333	5.069804567202	3.5638883020521	0.00036540149461247	0.0087755083947198	0.0087755083947198	1
561	Fcer1g	13.87994273	1.508714903	3.2016094999347	3.3825920097033	3.5500855154448	0.0003851060330401	0.0092322478402074	0.0092322478402074	1
562	Yars	19.17314123	52.80502161	-1.461588412182	-1.2806059024134	-3.544188445927	0.00039382364954793	0.0094244381899824	0.0094244381899824	1
563	Tspan3	104.3348237	68.64652809	0.60396210402627	0.78494461379494	3.5432061167481	0.00039529361715726	0.0094428132453784	0.0094428132453784	1
564	Gpx7	43.28660106	19.36184126	1.1607043664202	1.3416868761889	3.5418765490725	0.0003972913621939	0.0094737083867832	0.0094737083867832	1
565	Slc7a2	32.70020406	12.06971922	1.4379075238268	1.6188900335955	3.5402198653342	0.00039979381631612	0.0095165080276734	0.0095165080276734	1
567	Afap1	24.11345983	61.22867982	-1.344368911291	-1.1633864015223	-3.5382727336082	0.0004027538212731	0.00955315016279	0.0095346736465786	1
568	C1ra	23.76057993	6.53776458	1.8617007159752	2.0426832257439	3.5380869149478	0.00040303736800889	0.00954304500414	0.0095346736465786	1
569	Mars	19.64364776	53.55937906	-1.4470763766952	-1.2660938669266	-3.5378541821373	0.00040339276562594	0.0095346736465786	0.0095346736465786	1
570	Vldlr	8.351490965	32.43737042	-1.9575511848106	-1.776568675042	-3.5361693293049	0.00040597438644956	0.0095788588129125	0.0095786790800843	1
571	Bhlhe41	16.35010203	2.64025108	2.6305526014277	2.8115351111964	3.5357112189926	0.00040667899135461	0.0095786790800843	0.0095786790800843	1
572	Sema3d	21.87855379	5.531954645	1.9836561432779	2.1646386530466	3.5225292436638	0.00042744988049315	0.010050303221595	0.010050303221595	1
573	Epha2	19.17314123	52.55356912	-1.4547020264281	-1.2737195166595	-3.5209252531041	0.00043004382156015	0.010093646345833	0.010093646345833	1
574	Pcsk6	17.76162163	50.03904428	-1.4942909297672	-1.3133084199985	-3.5182155084998	0.00043445937846798	0.010179519479122	0.010179519479122	1
576	Icam1	27.99513873	9.17801566	1.6089221558835	1.7899046656522	3.5158966341847	0.00043827157914592	0.010233184840162	0.010233184840162	1
577	Nfe2l1	101.1589046	176.0167387	-0.7990893116898	-0.61810680192113	-3.5037409945282	0.00045877133112377	0.010693267993559	0.010693267993559	1
578	Crispld1	11.40978343	0	4.1819136975625	4.3628962073312	3.5029375585002	0.00046015731944241	0.010707016936299	0.010707016936299	1
579	Anxa8	2.587785933	18.98466253	-2.8750441692775	-2.6940616595088	-3.4993105888906	0.00046646288514735	0.010834990228578	0.010834990228578	1
581	Srrm2	67.87056742	128.2407668	-0.91799697736259	-0.73701446759392	-3.4930459255035	0.00047754437276504	0.011054207003988	0.011054207003988	1
582	Stt3b	57.75467695	113.279344	-0.97187513069606	-0.79089262092739	-3.4901561764626	0.00048273834377576	0.011155237088385	0.011155237088385	1
583	Tyrobp	15.76196886	2.514524838	2.6480900467919	2.8290725565606	3.4825899877736	0.00049658829020611	0.011455601912491	0.011455601912491	1
584	Itih5	11.2921568	0	4.166963356518	4.3479458662867	3.4819017162134	0.00049786638975814	0.01146541965044	0.01146541965044	1
585	3632451O06Rik	17.2911151	3.26888229	2.4031615782622	2.5841440880308	3.4762803882166	0.00050842043483332	0.011688455432604	0.011688455432604	1
586	Pdia4	72.22275285	134.2756264	-0.89467213536441	-0.71368962559574	-3.4752186534971	0.00051043711197836	0.011714793035831	0.011714793035831	1
587	Ddr1	43.05134779	90.77434667	-1.0762262373958	-0.89524372762713	-3.4730338135417	0.00051461051662083	0.011790454579273	0.011790454579273	1
588	Rin1	2.470159299	18.48175756	-2.9034259708646	-2.7224434610959	-3.4719055804317	0.00051677805991595	0.0118199798092	0.0118199798092	1
589	Esd	30.81817793	71.41250541	-1.2123951665098	-1.0314126567411	-3.4661496329982	0.00052796935830586	0.012055449745086	0.012055449745086	1
590	Ctnna1	78.57459105	143.0764633	-0.86465159848633	-0.68366908871766	-3.454368426483	0.00055158328621451	0.012573294264913	0.012573294264913	1
591	Pcgf3	16.5853553	47.27306696	-1.511108547618	-1.3301260378494	-3.4532975148213	0.00055377787274506	0.01260196042394	0.01260196042394	1
592	Eif3b	61.63635585	118.4341199	-0.94223129700162	-0.76124878723295	-3.4526380666508	0.00055513330301101	0.012611465865194	0.012611465865194	1
593	Mthfd1l	6.469464832	27.78549946	-2.1026138943376	-1.9216313845689	-3.4521389527192	0.00055616123595912	0.012613511741002	0.012613511741002	1
594	Crip1	12.7036764	1.257262419	3.3368883591078	3.5178708688765	3.450315564644	0.00055993162048536	0.012677643710282	0.012677643710282	1
595	Ran	34.81748346	77.44736502	-1.1534042236893	-0.97242171392065	-3.4381802455289	0.00058563773545866	0.013237381351569	0.013230235101741	1
596	Osmr	19.7612744	52.67929536	-1.4145600591957	-1.233577549427	-3.4378717525173	0.0005863053104794	0.013230235101741	0.013230235101741	1
598	Cct6a	44.58049402	92.53451405	-1.0535789666666	-0.87259645689789	-3.431286900064	0.00060072490173636	0.013510282948917	0.013510282948917	1
599	St3gal1	31.05343119	11.56681426	1.42476111402	1.6057436237886	3.4297099645158	0.00060422674239361	0.013566353019118	0.013566353019118	1
601	Tril	11.2921568	0	3.9039289506842	4.0849114604529	3.4238167605419	0.00061748241680985	0.013817838641723	0.013817838641723	1
602	Aqp1	44.34524076	20.9962824	1.0786453722239	1.2596278819926	3.41387729484	0.00064045413214636	0.014308085752884	0.014308085752884	1
603	Pdlim4	20.4670342	5.154775919	1.9893204427545	2.1703029525232	3.4125649774795	0.0006435458286801	0.014353313183945	0.014326703686348	1
604	Atoh8	13.4094362	41.11248111	-1.6163278598069	-1.4353453500383	-3.4123684344132	0.00064401005909281	0.014339886233012	0.014326703686348	1
605	Fgfr1	136.2116414	98.69509991	0.46479964577152	0.64578215554019	3.4121682175177	0.00064448328725114	0.014326703686348	0.014326703686348	1
606	Glce	11.88028996	38.22077754	-1.6857870797603	-1.5048045699916	-3.4081108269388	0.00065414320843386	0.014517445561431	0.014517445561431	1
607	Crlf1	32.70020406	73.67557777	-1.1718868304862	-0.99090432071755	-3.4062087433243	0.00065871793325871	0.014594888771658	0.014594888771658	1
608	Wbp5	57.75467695	31.30583424	0.88350623334401	1.0644887431127	3.4057339005191	0.00065986461489444	0.014596248693611	0.014596248693611	1
609	Efs	24.70159299	7.669300757	1.687437131144	1.8684196409126	3.400880683786	0.00067169138693555	0.014833460530207	0.014833460530207	1
610	Entpd3	10.2335171	0	4.7619099458118	4.9428924555805	3.3990916800788	0.00067610048960579	0.01490635325362	0.01490635325362	1
611	Pld3	80.69187045	50.16477053	0.68574878114195	0.86673129091062	3.3921312222706	0.00069351218045797	0.015265213281472	0.015254232245626	1
612	Smpdl3a	23.17244676	6.789217064	1.771093268412	1.9520757781807	3.3918803200455	0.0006941475302493	0.015254232245626	0.015254232245626	1
613	Ncor2	64.69464832	121.8287284	-0.91313609545566	-0.732153585687	-3.3849713438357	0.00071185685689127	0.015617883961388	0.015617883961388	1
614	Cad	29.05377843	67.51499191	-1.2164820949418	-1.0354995851732	-3.3811807070186	0.00072175059965856	0.015809159307505	0.015809159307505	1
616	Rpa1	23.40770003	58.21125001	-1.3143148113456	-1.1333323015769	-3.3784022952907	0.00072908335560336	0.015917925405048	0.015917925405048	1
617	Mcm5	6.587091465	27.40832074	-2.0569004515579	-1.8759179417893	-3.3736842348048	0.00074169395027485	0.016167004760529	0.016167004760529	1
618	Capn2	98.92399861	170.2333316	-0.78312108239964	-0.60213857263097	-3.3659638315424	0.00076276709011672	0.0165994410922	0.0165994410922	1
619	Acly	41.16932166	86.3739282	-1.0690262256332	-0.88804371586455	-3.3647415902986	0.00076615377452824	0.016646206968708	0.016646206968708	1
620	Tars	27.99513873	65.50337204	-1.2263928475331	-1.0454103377644	-3.3565266266225	0.00078928120537883	0.017121036985709	0.017121036985709	1
621	Palld	94.92469308	164.4499244	-0.79279301064695	-0.61181050087828	-3.3557783072848	0.00079141982162318	0.017139782900177	0.017139782900177	1
622	Slc8a3	10.586397	0	4.0738539521265	4.2548364618952	3.3528028200445	0.00079997676392909	0.017297246781483	0.017297246781483	1
623	Wdr1	65.87091465	122.9602646	-0.90047868679637	-0.71949617702771	-3.3492088790385	0.00081042672970459	0.01749507076693	0.01749507076693	1
624	Ppp1r3b	29.05377843	10.68673056	1.4429052473157	1.6238877570843	3.3443930616129	0.00082462813911364	0.017773115132916	0.017773115132916	1
625	Vcan	58.81331665	112.5249865	-0.93603063606025	-0.75504812629159	-3.3415578219136	0.00083309662233482	0.01792690635805	0.01792690635805	1
626	Hp	9.763010564	0	6.2789683816371	6.4599508914058	3.3359516055383	0.00085007960367057	0.018263131932533	0.018263131932533	1
627	Ctsf	29.17140506	10.81245681	1.4318605063061	1.6128430160748	3.3347406462465	0.00085378989538884	0.018313589000135	0.018313589000135	1
628	Bace2	15.40908896	2.765977322	2.4779203340034	2.658902843772	3.3331179719523	0.00085878519955387	0.018391404695541	0.018391404695541	1
629	Irf7	15.8795955	3.017429806	2.3957820479701	2.5767645577388	3.3261052195015	0.00088068676630267	0.018830455198735	0.018830455198735	1
630	Bcl11b	4.469812066	22.37927106	-2.3238769660223	-2.1428944562537	-3.3249015287753	0.00088449768630284	0.018881919655693	0.018879794362951	1
631	Stat2	30.23004476	11.56681426	1.3859915440018	1.5669740537705	3.3244906814654	0.00088580193642814	0.018879794362951	0.018879794362951	1
632	Lcp1	28.11276536	10.1838256	1.4649457557215	1.6459282654902	3.3217235773931	0.00089463275704737	0.019037841692294	0.019037841692294	1
633	Hcfc1r1	33.52359049	13.82988661	1.2773873468245	1.4583698565931	3.3201834982922	0.00089958297940616	0.019112940742549	0.019112940742549	1
634	Ankrd52	28.46564526	65.75482452	-1.2078749476168	-1.0268924378481	-3.3140126239302	0.00091967354967156	0.019508974084437	0.019508974084437	1
635	Mdm2	26.23073923	62.10876351	-1.2435383802808	-1.0625558705121	-3.3121322982876	0.00092587749731273	0.019609647970644	0.019609647970644	1
636	Lims1	45.75676036	92.40878781	-1.0140451433268	-0.83306263355813	-3.296110544118	0.00098033432556077	0.020730371610797	0.020699049710956	1
637	Slc44a2	81.28000361	51.67348543	0.65347626787005	0.83445877763872	3.2960939604905	0.00098039219762653	0.020699049710956	0.020699049710956	1
638	Sel1l	57.51942369	109.8847354	-0.93386986269702	-0.75288735292835	-3.2938960665655	0.00098809026599228	0.020828880857884	0.020828880857884	1
639	Tmed3	56.69603725	31.43156048	0.85103400274598	1.0320165125146	3.2898994634668	0.0010022318517376	0.021093922025069	0.021093922025069
640	Lifr	26.11311259	9.052289418	1.5284198159958	1.7094023257644	3.2884894508696	0.0010072655919548	0.021166742103438	0.021166742103438
641	Utp20	12.82130303	38.84940875	-1.5993497517785	-1.4183672420099	-3.2875358517782	0.0010106831926884	0.02120542630026	0.02120542630026
642	C4b	10.2335171	0	4.0249443516456	4.2059268614142	3.2862909676104	0.0010151608821385	0.02126619735807	0.02126619735807
643	Nenf	30.11241813	11.6925405	1.3647701401568	1.5457526499255	3.2851397521644	0.0010193179918338	0.021320074140237	0.021320074140237
644	Masp1	8.233864331

年龄	刷牙说明	推荐牙膏使用	特别注意事项
		低龋齿风险小朋友*	中高龋齿风险小朋友#
0-17个月	每天一至两次开始教小朋友刷牙：吐出牙膏，不要吞咽	不使用牙膏	0.05%的儿童牙膏，米粒大小
18个月-6岁	每天两次吐出牙膏，不要吞咽	含氟0.1%~0.15%牙膏	0.05%的儿童牙膏，绿豆大小或者含氟0.1%~0.15%的含氟牙膏，米粒大小
6-12岁	每天至少两次吐出牙膏，不要吞咽	含氟0.1%~0.15%牙膏	每天刷牙大于两次
13岁及以上	每天至少两次吐出牙膏，不要吞咽	含氟0.1%~0.15%牙膏	每天刷牙大于两次
13岁及以上	每天至少两次吐出牙膏，不要吞咽	或者按照牙医专业推荐：使用高含氟0.5%的牙膏，每天两次
*低龋齿风险 – 居住在社区水氟化物区域。儿童：自身或父母/照顾者和兄弟姐妹中没有新的龋齿或非龋齿病变；成年人：没有以下中度或高度风险因素。改编自CAMBRA（https://www.cdafoundation.org/Portals/0/pdfs/cambra_handbook.pdf ）
#中高龋齿风险因素 – 活跃的龋齿，氟化物暴露不足；高糖饮食；口腔卫生差 – 中；唾液分泌不足；未经治疗的龋齿的个人或家族病史；正在正畸治疗过程；其他个体因素，如低矿化牙齿，多种药物，特殊健康护理需求。

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Detection of the separated root canal instrument on panoramic radiograph: A comparison of LSTM and CNN deep learning methods

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